De Clercq E - Search Results

1

Antiviral activity of the 3'-amino derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine.

De Clercq E, Descamps J, Balzarini J, Fukui T, Allaudeen HS. De Clercq E, et al. Biochem J. 1983 May 1;211(2):439-45. doi: 10.1042/bj2110439. Biochem J. 1983. PMID: 6307280 Free PMC article.

2

Antiviral activity of O'-methylated derivatives of adenine arabinoside.

de Clercq E, Descamps J, Krajeswka E, Shugar D. de Clercq E, et al. Biochem Pharmacol. 1977 Apr 15;26(8):794-7. doi: 10.1016/0006-2952(77)90228-3. Biochem Pharmacol. 1977. PMID: 193517 No abstract available.

3

(E)-5-(2-Bromovinyl)-2'-deoxyuridine: a potent and selective anti-herpes agent.

De Clercq E, Descamps J, De Somer P, Barr PJ, Jones AS, Walker RT. De Clercq E, et al. Among authors: de somer p. Proc Natl Acad Sci U S A. 1979 Jun;76(6):2947-51. doi: 10.1073/pnas.76.6.2947. Proc Natl Acad Sci U S A. 1979. PMID: 223163 Free PMC article.

4

Pharmacokinetics of E-5-(2-bromovinyl)-2'-deoxyuridine in mice.

de Clercq E, Descamps J, de Somer P, Barr PJ, Jones AS, Walker RT. de Clercq E, et al. Among authors: de somer p. Antimicrob Agents Chemother. 1979 Aug;16(2):234-6. doi: 10.1128/AAC.16.2.234. Antimicrob Agents Chemother. 1979. PMID: 225987 Free PMC article.

5

Antiviral activity of 5-methylthiomethyl-2'-deoxyuridine and other 5-substituted 2'-deoxyuridines.

De Clercq E, Descamps J, Schmidt CL, Mertes MP. De Clercq E, et al. Biochem Pharmacol. 1979 Nov 15;28(22):3249-54. doi: 10.1016/0006-2952(79)90117-5. Biochem Pharmacol. 1979. PMID: 230848 No abstract available.

6

Assay method for monitoring the inhibitory effects of antimetabolites on the activity of inosinate dehydrogenase in intact human CEM lymphocytes.

Balzarini J, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Biochem J. 1992 Nov 1;287 ( Pt 3)(Pt 3):785-90. doi: 10.1042/bj2870785. Biochem J. 1992. PMID: 1359876 Free PMC article.

7

9-Beta-D-arabinofuranosyladenine 5'-monophosphate (araAMP) is converted directly to its antivirally active 5'-triphosphate form by 5-phosphoribosyl-1-pyrophosphate (PRPP) synthetase.

Balzarini J, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Biochem Biophys Res Commun. 1990 Dec 31;173(3):781-7. doi: 10.1016/s0006-291x(05)80855-1. Biochem Biophys Res Commun. 1990. PMID: 1702630

8

The antiviral activity of 9-beta-D-arabinofuranosyladenine is enhanced by the 2',3'-dideoxyriboside, the 2',3'-didehydro-2',3'-dideoxyriboside and the 3'-azido-2',3'-dideoxyriboside of 2,6-diaminopurine.

Balzarini J, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Biochem Biophys Res Commun. 1989 Feb 28;159(1):61-7. doi: 10.1016/0006-291x(89)92404-2. Biochem Biophys Res Commun. 1989. PMID: 2538128

9

Inhibitory effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and related compounds on herpes simplex virus (HSV)-infected cells and HSV thymidine kinase gene-transformed cells.

Balzarini J, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Methods Find Exp Clin Pharmacol. 1989 Jun;11(6):379-89. Methods Find Exp Clin Pharmacol. 1989. PMID: 2545982 Review. No abstract available.

10

Synthesis and antiviral activity of the enantiomeric forms of carba-5-iodo-2'-deoxyuridine and carba-(E)-5-(2-bromovinyl)-2'-deoxyuridine.

Balzarini J, Baumgartner H, Bodenteich M, De Clercq E, Griengl H. Balzarini J, et al. Among authors: de clercq e. J Med Chem. 1989 Aug;32(8):1861-5. doi: 10.1021/jm00128a029. J Med Chem. 1989. PMID: 2547072

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