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CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair.
Provencher L, Nartey W, Brownlee PM, Atkins AW, Gagné JP, Baudrier L, Ting NSY, Piett CG, Fang S, Pearson DD, Moore S, Billon P, Nagel ZD, Poirier GG, Williams GJ, Goodarzi AA. Provencher L, et al. Among authors: williams gj. Nat Commun. 2025 Jan 25;16(1):1026. doi: 10.1038/s41467-025-56085-5. Nat Commun. 2025. PMID: 39863586 Free PMC article.
ATM phosphorylates the FATC domain of DNA-PK cs at threonine 4102 to promote non-homologous end joining.
Lu H, Zhang Q, Laverty DJ, Puncheon AC, Williams GJ, Nagel ZD, Chen BP, Davis AJ. Lu H, et al. Among authors: williams gj. bioRxiv [Preprint]. 2023 Feb 2:2023.02.02.526879. doi: 10.1101/2023.02.02.526879. bioRxiv. 2023. Update in: Nucleic Acids Res. 2023 Jul 21;51(13):6770-6783. doi: 10.1093/nar/gkad505. PMID: 36778257 Free PMC article. Updated. Preprint.
Diagnostic development and needs for laser driven MeV x-ray radiography.
Rusby DR, Williams GJ, Kerr SM, Aghedo A, Alessi D, Anderson S, Hill M, Rodger I, Rubery M, Selwood MP, Treffert F, Mackinnon AJ. Rusby DR, et al. Among authors: williams gj. Rev Sci Instrum. 2024 Dec 1;95(12):123512. doi: 10.1063/5.0219493. Rev Sci Instrum. 2024. PMID: 39665600
462 results