Liu Z - Search Results

1

Hepatocellular CMPK2 promotes the development of metabolic dysfunction-associated steatohepatitis.

Zhu S, Liao L, Zhong Y, Liu Z, Lu J, Yang Z, Xiao Y, Xu X. Zhu S, et al. Among authors: liu z. J Hepatol. 2025 Jan 22:S0168-8278(25)00014-5. doi: 10.1016/j.jhep.2025.01.008. Online ahead of print. J Hepatol. 2025. PMID: 39855350

2

Targeting SLITRK4 Restrains Proliferation and Liver Metastasis in Colorectal Cancer via Regulating PI3K/AKT/NFκB Pathway and Tumor-Associated Macrophage.

Sun X, Zhang J, Dong B, Xiong Q, Wang X, Gu Y, Wang Z, Liu H, Zhang J, He X, Liu H, Zhong Y, Yi C, Chi X, Liu Z, Pang X, Cui Y. Sun X, et al. Among authors: liu z, liu h. Adv Sci (Weinh). 2025 Jan;12(1):e2400367. doi: 10.1002/advs.202400367. Epub 2024 Nov 5. Adv Sci (Weinh). 2025. PMID: 39499724 Free PMC article.

3

Optimization of 4-arylthiophene-3-carboxylic acid derivatives as inhibitors of ANO1: Lead optimization studies toward their analgesic efficacy for inflammatory pain.

Wang Y, Hu X, Huang H, Jin Z, Gao J, Guo Y, Zhong Y, Li Z, Zong X, Wang K, Zhang L, Liu Z. Wang Y, et al. Among authors: liu z. Eur J Med Chem. 2022 Jul 5;237:114413. doi: 10.1016/j.ejmech.2022.114413. Epub 2022 Apr 26. Eur J Med Chem. 2022. PMID: 35512566

4

Discovery of 2-(2-aminobenzo[d]thiazol-6-yl) benzo[d]oxazol-5-amine derivatives that regulated HPV relevant cellular pathway and prevented cervical cancer from abnormal proliferation.

Jiao P, Wang Y, Mao B, Wang B, Zhong Y, Jin H, Zhang L, Zhang L, Liu Z. Jiao P, et al. Among authors: liu z. Eur J Med Chem. 2020 Oct 15;204:112556. doi: 10.1016/j.ejmech.2020.112556. Epub 2020 Jul 13. Eur J Med Chem. 2020. PMID: 32739649

5

Identification of a small chemical as a lysosomal calcium mobilizer and characterization of its ability to inhibit autophagy and viral infection.

Zhang K, Huang L, Cai Y, Zhong Y, Chen N, Gao F, Zhang L, Li Q, Liu Z, Zhang R, Zhang L, Yue J. Zhang K, et al. Among authors: liu z. FEBS J. 2023 Nov;290(22):5353-5372. doi: 10.1111/febs.16920. Epub 2023 Aug 17. FEBS J. 2023. PMID: 37528513 Free article.

6

Deep-Learning-Driven Discovery of SN3-1, a Potent NLRP3 Inhibitor with Therapeutic Potential for Inflammatory Diseases.

Shi C, Gao T, Lyu W, Qiang B, Chen Y, Chen Q, Zhang L, Liu Z. Shi C, et al. Among authors: liu z. J Med Chem. 2024 Oct 10;67(19):17833-17854. doi: 10.1021/acs.jmedchem.4c01857. Epub 2024 Sep 20. J Med Chem. 2024. PMID: 39302813

7

NSD3: Advances in cancer therapeutic potential and inhibitors research.

Xiu S, Chi X, Jia Z, Shi C, Zhang X, Li Q, Gao T, Zhang L, Liu Z. Xiu S, et al. Among authors: liu z. Eur J Med Chem. 2023 Aug 5;256:115440. doi: 10.1016/j.ejmech.2023.115440. Epub 2023 May 9. Eur J Med Chem. 2023. PMID: 37182335 Review.

8

Medicinal chemistry perspective of TRPM2 channel inhibitors: where we are and where we might be heading?

Zhang H, Zhao S, Yu J, Yang W, Liu Z, Zhang L. Zhang H, et al. Among authors: liu z. Drug Discov Today. 2020 Dec;25(12):2326-2334. doi: 10.1016/j.drudis.2020.09.039. Epub 2020 Oct 13. Drug Discov Today. 2020. PMID: 33065292 Review.

9

Discovery of NLRP3 inhibitors using machine learning: Identification of a hit compound to treat NLRP3 activation-driven diseases.

Shi C, Zhang X, Chi X, Zhou YR, Lyu W, Gao T, Zhou J, Chen Y, Yi C, Sun X, Zhang L, Liu Z. Shi C, et al. Among authors: liu z. Eur J Med Chem. 2023 Nov 15;260:115784. doi: 10.1016/j.ejmech.2023.115784. Epub 2023 Sep 1. Eur J Med Chem. 2023. PMID: 37672931

10

Discovery of novel and selective farnesoid X receptor antagonists through structure-based virtual screening, preliminary structure-activity relationship study, and biological evaluation.

Dou X, Huo T, Liu Y, Pang Z, Su L, Zhao X, Peng X, Liu Z, Zhang L, Jiao N. Dou X, et al. Among authors: liu z, liu y. Eur J Med Chem. 2024 Apr 5;269:116323. doi: 10.1016/j.ejmech.2024.116323. Epub 2024 Mar 18. Eur J Med Chem. 2024. PMID: 38547735

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