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Page 1
Different PD-L1 Assays Reveal Distinct Immunobiology and Clinical Outcomes in Urothelial Cancer.
Galsky MD, Kockx M, Roels J, Van Elzen R, Guan X, Yuen K, Rishipathak D, Anker JF, Gnjatic S, Izadmehr S, Sanjabi S, Johnston RJ, Peterson M, Koeppen H, David JM, Gupta S, Bamias A, Arranz JA, Kikuchi E, De Santis M, Davis ID, Williams P, Bernhard S, Mellman I, Grande E, Banchereau R, Mariathasan S. Galsky MD, et al. Among authors: roels j. Cancer Immunol Res. 2025 Jan 24. doi: 10.1158/2326-6066.CIR-24-0649. Online ahead of print. Cancer Immunol Res. 2025. PMID: 39853278
Molecular heterogeneity in urothelial carcinoma and determinants of clinical benefit to PD-L1 blockade.
Hamidi H, Senbabaoglu Y, Beig N, Roels J, Manuel C, Guan X, Koeppen H, Assaf ZJ, Nabet BY, Waddell A, Yuen K, Maund S, Sokol E, Giltnane JM, Schedlbauer A, Fuentes E, Cowan JD, Kadel EE 3rd, Degaonkar V, Andreev-Drakhlin A, Williams P, Carter C, Gupta S, Steinberg E, Loriot Y, Bellmunt J, Grivas P, Rosenberg J, van der Heijden MS, Galsky MD, Powles T, Mariathasan S, Banchereau R. Hamidi H, et al. Among authors: roels j. Cancer Cell. 2024 Dec 9;42(12):2098-2112.e4. doi: 10.1016/j.ccell.2024.10.016. Epub 2024 Nov 21. Cancer Cell. 2024. PMID: 39577421
Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia.
Rahman S, Bloye G, Farah N, Demeulemeester J, Costa JR, O'Connor D, Pocock R, Rapoz-D'Silva T, Turna A, Wang L, Lee S, Fielding AK, Roels J, Jaksik R, Dawidowska M, Van Vlierberghe P, Hadjur S, Hughes JR, Davies JOJ, Gutierrez A, Kelliher MA, Van Loo P, Dawson MA, Mansour MR. Rahman S, et al. Among authors: roels j. Blood. 2024 Nov 28;144(22):2319-2326. doi: 10.1182/blood.2024024300. Blood. 2024. PMID: 39316719 Free article.
ThymoSpheres culture: A model to study human polyclonal unconventional T cells.
Billiet L, Jansen H, Pille M, Boehme L, Sanchez Sanchez G, De Cock L, Goetgeluk G, Pascal E, De Munter S, Deseins L, Ingels J, Michiels T, De Vos R, Zolfaghari A, Vandamme N, Roels J, Kerre T, Dmitriev RI, Taghon T, Vermijlen D, Vandekerckhove B. Billiet L, et al. Among authors: roels j. Eur J Immunol. 2024 Dec;54(12):e2451265. doi: 10.1002/eji.202451265. Epub 2024 Sep 9. Eur J Immunol. 2024. PMID: 39246170 Free PMC article.
The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival.
Stanulović VS, Al Omair S, Reed MAC, Roberts J, Potluri S, Fulton-Ward T, Gudgeon N, Bishop EL, Roels J, Perry TA, Sarkar S, Pratt G, Taghon T, Dimeloe S, Günther UL, Ludwig C, Hoogenkamp M. Stanulović VS, et al. Among authors: roels j. Haematologica. 2024 Nov 1;109(11):3505-3519. doi: 10.3324/haematol.2023.283471. Haematologica. 2024. PMID: 38813748 Free PMC article.
An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade.
Houbaert D, Nikolakopoulos AP, Jacobs KA, Meçe O, Roels J, Shankar G, Agrawal M, More S, Ganne M, Rillaerts K, Boon L, Swoboda M, Nobis M, Mourao L, Bosisio F, Vandamme N, Bergers G, Scheele CLGJ, Agostinis P. Houbaert D, et al. Among authors: roels j. Cell Rep. 2024 Apr 23;43(4):114020. doi: 10.1016/j.celrep.2024.114020. Epub 2024 Mar 28. Cell Rep. 2024. PMID: 38554280 Free article.
Brain exposure to SARS-CoV-2 virions perturbs synaptic homeostasis.
Partiot E, Hirschler A, Colomb S, Lutz W, Claeys T, Delalande F, Deffieu MS, Bare Y, Roels JRE, Gorda B, Bons J, Callon D, Andreoletti L, Labrousse M, Jacobs FMJ, Rigau V, Charlot B, Martens L, Carapito C, Ganesh G, Gaudin R. Partiot E, et al. Among authors: roels jre. Nat Microbiol. 2024 May;9(5):1189-1206. doi: 10.1038/s41564-024-01657-2. Epub 2024 Mar 28. Nat Microbiol. 2024. PMID: 38548923
100 results