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Engineering synthetic phosphorylation signaling networks in human cells.
Yang X, Rocks JW, Jiang K, Walters AJ, Rai K, Liu J, Nguyen J, Olson SD, Mehta P, Collins JJ, Daringer NM, Bashor CJ. Yang X, et al. Among authors: collins jj. Science. 2025 Jan 3;387(6729):74-81. doi: 10.1126/science.adm8485. Epub 2025 Jan 2. Science. 2025. PMID: 39745956
An explainable deep learning platform for molecular discovery.
Wong F, Omori S, Li A, Krishnan A, Lach RS, Rufo J, Wilson MZ, Collins JJ. Wong F, et al. Among authors: collins jj. Nat Protoc. 2024 Dec 9. doi: 10.1038/s41596-024-01084-x. Online ahead of print. Nat Protoc. 2024. PMID: 39653800 Review.
Accurate RNA 3D structure prediction using a language model-based deep learning approach.
Shen T, Hu Z, Sun S, Liu D, Wong F, Wang J, Chen J, Wang Y, Hong L, Xiao J, Zheng L, Krishnamoorthi T, King I, Wang S, Yin P, Collins JJ, Li Y. Shen T, et al. Among authors: collins jj. Nat Methods. 2024 Dec;21(12):2287-2298. doi: 10.1038/s41592-024-02487-0. Epub 2024 Nov 21. Nat Methods. 2024. PMID: 39572716 Free PMC article.
Deep generative design of RNA aptamers using structural predictions.
Wong F, He D, Krishnan A, Hong L, Wang AZ, Wang J, Hu Z, Omori S, Li A, Rao J, Yu Q, Jin W, Zhang T, Ilia K, Chen JX, Zheng S, King I, Li Y, Collins JJ. Wong F, et al. Among authors: collins jj. Nat Comput Sci. 2024 Nov;4(11):829-839. doi: 10.1038/s43588-024-00720-6. Epub 2024 Nov 6. Nat Comput Sci. 2024. PMID: 39506080
UROPOT: study protocol for a randomized, double-blind phase I/II trial for metabolism-based potentiation of antimicrobial prophylaxis in the urological tract.
Stritt K, Roth B, Masnada A, Hammann F, Jacot D, Domingos-Pereira S, Crettenand F, Bohner P, Sommer I, Bréat E, Sauser J, Derré L, Haschke M, Collins JJ, McKinney J, Meylan S. Stritt K, et al. Among authors: collins jj. Trials. 2024 Oct 15;25(1):682. doi: 10.1186/s13063-024-08526-7. Trials. 2024. PMID: 39407325 Free PMC article.
O-glycosylation contributes to mammalian glycoRNA biogenesis.
Porat J, Watkins CP, Jin C, Xie X, Tan X, Lebedenko CG, Hemberger H, Shin W, Chai P, Collins JJ, Garcia BA, Bojar D, Flynn RA. Porat J, et al. Among authors: collins jj. bioRxiv [Preprint]. 2024 Aug 29:2024.08.28.610074. doi: 10.1101/2024.08.28.610074. bioRxiv. 2024. PMID: 39257776 Free PMC article. Preprint.
855 results