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HMGB1 encapsulated in podocyte-derived exosomes plays a central role in glomerular endothelial cell injury in lupus nephritis by regulating TRIM27 expression.
Liu J, Zhao T, Cui H, Tian Y, Miao X, Xing L, Wang X, Huang J, Liu Q, Zhang W, Shi K, Liu Y, Jia B, Kang L, Tian Y, Yuan W, He S, Feng X, Liu S. Liu J, et al. Among authors: liu y, liu s, liu q. Lab Invest. 2025 Jan 21:104096. doi: 10.1016/j.labinv.2025.104096. Online ahead of print. Lab Invest. 2025. PMID: 39848602
HMGB1 protein promotes glomerular mesangial matrix deposition via TLR2 in lupus nephritis.
Feng X, Yang R, Tian Y, Miao X, Guo H, Gao F, Yang L, Zhao S, Zhang W, Liu J, Li H, Tian Y, Zhao L, Wang S, Liu W, Wang K, Li Y, Wang Z, Liu Q, Wang C, Liu S. Feng X, et al. Among authors: liu j, liu s, liu q, liu w. J Cell Physiol. 2020 Jun;235(6):5111-5119. doi: 10.1002/jcp.29379. Epub 2019 Oct 30. J Cell Physiol. 2020. PMID: 31667864
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