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VCP regulates early tau seed amplification via specific cofactors.
Batra S, Vaquer-Alicea J, Valdez C, Taylor SP, Manon VA, Vega AR, Kashmer OM, Kolay S, Lemoff A, Cairns NJ, White CL 3rd, Diamond MI. Batra S, et al. Among authors: vaquer alicea j. Mol Neurodegener. 2025 Jan 7;20(1):2. doi: 10.1186/s13024-024-00783-z. Mol Neurodegener. 2025. PMID: 39773263 Free PMC article.
Essential tremor with tau pathology features seeds indistinguishable in conformation from Alzheimer's disease and primary age-related tauopathy.
Saez-Calveras N, Vaquer-Alicea J, White CL 3rd, Tak Y, Cosentino S, Faust PL, Louis ED, Diamond MI. Saez-Calveras N, et al. Among authors: vaquer alicea j. bioRxiv [Preprint]. 2024 Oct 20:2024.10.12.617973. doi: 10.1101/2024.10.12.617973. bioRxiv. 2024. Update in: Acta Neuropathol. 2025 Jan 8;149(1):6. doi: 10.1007/s00401-024-02843-6 PMID: 39464029 Free PMC article. Updated. Preprint.
Cryo-EM structure of Alzheimer's disease tau filaments with PET ligand MK-6240.
Kunach P, Vaquer-Alicea J, Smith MS, Monistrol J, Hopewell R, Moquin L, Therriault J, Tissot C, Rahmouni N, Massarweh G, Soucy JP, Guiot MC, Shoichet BK, Rosa-Neto P, Diamond MI, Shahmoradian SH. Kunach P, et al. Among authors: vaquer alicea j. Nat Commun. 2024 Oct 1;15(1):8497. doi: 10.1038/s41467-024-52265-x. Nat Commun. 2024. PMID: 39353896 Free PMC article.
VCP regulates early tau seed amplification via specific cofactors.
Batra S, Vaquer-Alicea JI, Valdez C, Taylor SP, Manon VA, Vega AR, Kashmer OM, Kolay S, Lemoff A, Cairns NJ, White CL, Diamond MI. Batra S, et al. Among authors: vaquer alicea ji. Res Sq [Preprint]. 2024 May 22:rs.3.rs-4307848. doi: 10.21203/rs.3.rs-4307848/v1. Res Sq. 2024. Update in: Mol Neurodegener. 2025 Jan 7;20(1):2. doi: 10.1186/s13024-024-00783-z PMID: 38826306 Free PMC article. Updated. Preprint.
Cryo-EM structure of Alzheimer's disease tau filaments with PET ligand MK-6240.
Kunach P, Vaquer-Alicea J, Smith MS, Hopewell R, Monistrol J, Moquin L, Therriault J, Tissot C, Rahmouni N, Massarweh G, Soucy JP, Guiot MC, Shoichet BK, Rosa-Neto P, Diamond MI, Shahmoradian SH. Kunach P, et al. Among authors: vaquer alicea j. bioRxiv [Preprint]. 2023 Sep 22:2023.09.22.558671. doi: 10.1101/2023.09.22.558671. bioRxiv. 2023. Update in: Nat Commun. 2024 Oct 1;15(1):8497. doi: 10.1038/s41467-024-52265-x PMID: 37790438 Free PMC article. Updated. Preprint.
VCP increases or decreases tau seeding using specific cofactors.
Batra S, Vaquer-Alicea J 3rd, Manon VA, Kashmer OM, Lemoff A, Cairns NJ, White CL 3rd, Diamond MI. Batra S, et al. Among authors: vaquer alicea j 3rd. bioRxiv [Preprint]. 2023 Aug 30:2023.08.30.555637. doi: 10.1101/2023.08.30.555637. bioRxiv. 2023. PMID: 37693404 Free PMC article. Preprint.
Network of hotspot interactions cluster tau amyloid folds.
Mullapudi V, Vaquer-Alicea J, Bommareddy V, Vega AR, Ryder BD, White CL 3rd, Diamond MI, Joachimiak LA. Mullapudi V, et al. Among authors: vaquer alicea j. Nat Commun. 2023 Feb 16;14(1):895. doi: 10.1038/s41467-023-36572-3. Nat Commun. 2023. PMID: 36797278 Free PMC article.
20 results