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Page 1
CpG island methylator phenotype classification improves risk assessment in pediatric T-cell Acute Lymphoblastic Leukemia.
Schäfer Hackenhaar F, Refhagen N, Hagleitner MM, van Leeuwen FN, Marquart HV, Madsen HO, Landfors M, Osterman P, Schmiegelow K, Flaegstad T, Jonsson OG, Kanerva J, Abrahamsson J, Heyman M, Noren-Nystrom U, Hultdin M, Degerman S. Schäfer Hackenhaar F, et al. Among authors: van leeuwen fn. Blood. 2025 Jan 22:blood.2024026027. doi: 10.1182/blood.2024026027. Online ahead of print. Blood. 2025. PMID: 39841000
The Prognostic Effect of IKZF1 Deletions in ETV6::RUNX1 and High Hyperdiploid Childhood Acute Lymphoblastic Leukemia.
Østergaard A, Enshaei A, Pieters R, Vora A, Horstmann MA, Escherich G, Johansson B, Heyman M, Schmiegelow K, Hoogerbrugge PM, den Boer ML, Kuiper RP, Moorman AV, Boer JM, van Leeuwen FN. Østergaard A, et al. Among authors: van leeuwen fn. Hemasphere. 2023 May 4;7(5):e875. doi: 10.1097/HS9.0000000000000875. eCollection 2023 May. Hemasphere. 2023. PMID: 37153875 Free PMC article.
BTG1 regulates glucocorticoid receptor autoinduction in acute lymphoblastic leukemia.
van Galen JC, Kuiper RP, van Emst L, Levers M, Tijchon E, Scheijen B, Waanders E, van Reijmersdal SV, Gilissen C, van Kessel AG, Hoogerbrugge PM, van Leeuwen FN. van Galen JC, et al. Among authors: van reijmersdal sv, van emst l, van leeuwen fn, van kessel ag. Blood. 2010 Jun 10;115(23):4810-9. doi: 10.1182/blood-2009-05-223081. Epub 2010 Mar 30. Blood. 2010. PMID: 20354172 Free article.
Influence of genetic variants in TPMT and COMT associated with cisplatin induced hearing loss in patients with cancer: two new cohorts and a meta-analysis reveal significant heterogeneity between cohorts.
Hagleitner MM, Coenen MJ, Patino-Garcia A, de Bont ES, Gonzalez-Neira A, Vos HI, van Leeuwen FN, Gelderblom H, Hoogerbrugge PM, Guchelaar HJ, Te Loo MW. Hagleitner MM, et al. Among authors: van leeuwen fn. PLoS One. 2014 Dec 31;9(12):e115869. doi: 10.1371/journal.pone.0115869. eCollection 2014. PLoS One. 2014. PMID: 25551397 Free PMC article.
BTK inhibition sensitizes acute lymphoblastic leukemia to asparaginase by suppressing the amino acid response pathway.
Butler M, van Ingen Schenau DS, Yu J, Jenni S, Dobay MP, Hagelaar R, Vervoort BMT, Tee TM, Hoff FW, Meijerink JP, Kornblau SM, Bornhauser B, Bourquin JP, Kuiper RP, van der Meer LT, van Leeuwen FN. Butler M, et al. Among authors: van ingen schenau ds, van der meer lt, van leeuwen fn. Blood. 2021 Dec 9;138(23):2383-2395. doi: 10.1182/blood.2021011787. Blood. 2021. PMID: 34280258 Free PMC article. Clinical Trial.
Independent prognostic value of BCR-ABL1-like signature and IKZF1 deletion, but not high CRLF2 expression, in children with B-cell precursor ALL.
van der Veer A, Waanders E, Pieters R, Willemse ME, Van Reijmersdal SV, Russell LJ, Harrison CJ, Evans WE, van der Velden VH, Hoogerbrugge PM, Van Leeuwen F, Escherich G, Horstmann MA, Mohammadi Khankahdani L, Rizopoulos D, De Groot-Kruseman HA, Sonneveld E, Kuiper RP, Den Boer ML. van der Veer A, et al. Blood. 2013 Oct 10;122(15):2622-9. doi: 10.1182/blood-2012-10-462358. Epub 2013 Aug 23. Blood. 2013. PMID: 23974192 Free PMC article.
A First Step toward Personalized Medicine in Osteosarcoma: Pharmacogenetics as Predictive Marker of Outcome after Chemotherapy-Based Treatment.
Hagleitner MM, Coenen MJ, Gelderblom H, Makkinje RR, Vos HI, de Bont ES, van der Graaf WT, Schreuder HW, Flucke U, van Leeuwen FN, Hoogerbrugge PM, Guchelaar HJ, te Loo DM. Hagleitner MM, et al. Among authors: van der graaf wt, van leeuwen fn. Clin Cancer Res. 2015 Aug 1;21(15):3436-41. doi: 10.1158/1078-0432.CCR-14-2638. Epub 2015 Mar 31. Clin Cancer Res. 2015. PMID: 25829401
Clonal dynamics in pediatric B-cell precursor acute lymphoblastic leukemia with very early relapse.
Antić Ž, Yu J, Bornhauser BC, Lelieveld SH, van der Ham CG, van Reijmersdal SV, Morgado L, Elitzur S, Bourquin JP, Cazzaniga G, Eckert C, Camós M, Sutton R, Cavé H, Moorman AV, Sonneveld E, Geurts van Kessel A, van Leeuwen FN, Hoogerbrugge PM, Waanders E, Kuiper RP. Antić Ž, et al. Among authors: van reijmersdal sv, van der ham cg, van leeuwen fn. Pediatr Blood Cancer. 2022 Jan;69(1):e29361. doi: 10.1002/pbc.29361. Epub 2021 Oct 1. Pediatr Blood Cancer. 2022. PMID: 34597466 Free article.
A germ line mutation in cathepsin B points toward a role in asparaginase pharmacokinetics.
van der Meer LT, Waanders E, Levers M, Venselaar H, Roeleveld D, Boos J, Lanvers C, Brüggemann RJ, Kuiper RP, Hoogerbrugge PM, van Leeuwen FN, te Loo DM. van der Meer LT, et al. Among authors: van leeuwen fn. Blood. 2014 Nov 6;124(19):3027-9. doi: 10.1182/blood-2014-06-582627. Blood. 2014. PMID: 25377564 Free article. No abstract available.
Kinase activity profiling reveals active signal transduction pathways in pediatric acute lymphoblastic leukemia: a new approach for target discovery.
van der Sligte NE, Scherpen FJ, Meeuwsen-de Boer TG, Lourens HJ, Ter Elst A, Diks SH, Guryev V, Peppelenbosch MP, van Leeuwen FN, de Bont ES. van der Sligte NE, et al. Among authors: van leeuwen fn. Proteomics. 2015 Apr;15(7):1245-54. doi: 10.1002/pmic.201400286. Epub 2015 Jan 21. Proteomics. 2015. PMID: 25422122
84 results