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Transferrin promotes fatty acid oxidation and liver tumor growth through PHD2-mediated PPARα hydroxylation in an iron-dependent manner.
Qian X, Zhou Q, Ouyang Y, Wu X, Sun X, Wang S, Duan Y, Hu Z, Hou Y, Wang Z, Chen X, Wang KL, Shen Y, Dong B, Lin Y, Wen T, Tian Q, Guo Z, Li M, Xiao L, Wu Q, Meng Y, Liu G, Ying H, Zhou Y, Zhang W, Duan S, Bai X, Liu T, Zhan P, Lu Z, Xu D. Qian X, et al. Among authors: bai x. Proc Natl Acad Sci U S A. 2025 Feb 4;122(5):e2412473122. doi: 10.1073/pnas.2412473122. Epub 2025 Jan 31. Proc Natl Acad Sci U S A. 2025. PMID: 39888917
Oligodendrocyte precursor cells facilitate neuronal lysosome release.
Fang LP, Lin CH, Medlej Y, Zhao R, Chang HF, Guo Q, Wu Z, Su Y, Zhao N, Gobbo D, Wyatt A, Wahl V, Fiore F, Tu SM, Boehm U, Huang W, Bian S, Agarwal A, Lauterbach MA, Yi C, Niu J, Scheller A, Kirchhoff F, Bai X. Fang LP, et al. Among authors: bai x. Nat Commun. 2025 Jan 30;16(1):1175. doi: 10.1038/s41467-025-56484-8. Nat Commun. 2025. PMID: 39885146 Free PMC article.
Elevated protein lactylation promotes immunosuppressive microenvironment and therapeutic resistance in pancreatic ductal adenocarcinoma.
Sun K, Zhang X, Shi J, Huang J, Wang S, Li X, Lin H, Zhao D, Ye M, Zhang S, Qiu L, Yang M, Liao C, He L, Lao M, Song J, Lu N, Ji Y, Yang H, Liu L, Liu X, Chen Y, Yao S, Xu Q, Lin J, Mao Y, Zhou J, Zhi X, Sun K, Lu X, Bai X, Liang T. Sun K, et al. Among authors: bai x. J Clin Invest. 2025 Jan 30:e187024. doi: 10.1172/JCI187024. Online ahead of print. J Clin Invest. 2025. PMID: 39883522 Free article.
9,790 results