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Page 1
Thrombin-induced kynurenine 3-monooxygenase causes variations in the kynurenine pathway, leading to neurological deficits in a murine intracerebral hemorrhage model.
Ohnishi M, Banshoya K, Machida A, Kai T, Shimizu Y, Yano Y, Urabe Y, Tasaka S, Furutaguchi M, Shigemasa T, Akagi M, Maehara S, Hata T. Ohnishi M, et al. Among authors: machida a. J Pharmacol Sci. 2025 Feb;157(2):65-74. doi: 10.1016/j.jphs.2024.12.003. Epub 2024 Dec 12. J Pharmacol Sci. 2025. PMID: 39828395 Free article.
Development of a Water-Soluble Nanomicellar Formulation Loaded with Trans-Resveratrol Using Polyethylene Glycol Monostearate for the Treatment of Intracerebral Hemorrhage.
Banshoya K, Machida A, Kawamura S, Yamada T, Okada R, Kawamoto Y, Kimura H, Shibata S, Hieda Y, Kaneo Y, Tanaka T, Ohnishi M. Banshoya K, et al. Among authors: machida a. Pharmaceutics. 2024 Nov 15;16(11):1462. doi: 10.3390/pharmaceutics16111462. Pharmaceutics. 2024. PMID: 39598585 Free PMC article.
Intravenous glibenclamide for cerebral oedema after large hemispheric stroke (CHARM): a phase 3, double-blind, placebo-controlled, randomised trial.
Sheth KN, Albers GW, Saver JL, Campbell BCV, Molyneaux BJ, Hinson HE, Cordonnier C, Steiner T, Toyoda K, Wintermark M, Littauer R, Collins J, Lucas N, Nogueira RG, Simard JM, Wald M, Dawson K, Kimberly WT; CHARM Trial investigators. Sheth KN, et al. Lancet Neurol. 2024 Dec;23(12):1205-1213. doi: 10.1016/S1474-4422(24)00425-3. Lancet Neurol. 2024. PMID: 39577921 Clinical Trial.
Highly demarcated structural alterations in the brain and impaired social incentive learning in Tbx1 heterozygous mice.
Hiramoto T, Sumiyoshi A, Kato R, Yamauchi T, Takano T, Kang G, Esparza M, Matsumura B, Stevens LJ, Hiroi YJ, Tanifuji T, Ryoke R, Nonaka H, Machida A, Nomoto K, Mogi K, Kikusui T, Kawashima R, Hiroi N. Hiramoto T, et al. Among authors: machida a. Mol Psychiatry. 2024 Oct 27. doi: 10.1038/s41380-024-02797-x. Online ahead of print. Mol Psychiatry. 2024. PMID: 39463450
Paroxysmal sympathetic hyperactivity caused by neurosyphilis.
Fujiki S, Fujino M, Machida A. Fujiki S, et al. Among authors: machida a. BMJ Neurol Open. 2024 Oct 15;6(2):e000814. doi: 10.1136/bmjno-2024-000814. eCollection 2024. BMJ Neurol Open. 2024. PMID: 39415898 Free PMC article.
A Glycyrrhizin Derivative with a More Potent Inhibitory Activity against High-Mobility Group Box 1 Efficiently Discovered by Chemical Synthesis Inspired by the Bioconversion Products of an Endophytic Fungus Isolated from Licorice.
Machida A, Banshoya K, Miyamaru A, Eto T, Maehara S, Hieda Y, Hata T, Ohnishi M. Machida A, et al. J Med Chem. 2024 Sep 26;67(18):16328-16337. doi: 10.1021/acs.jmedchem.4c01213. Epub 2024 Sep 4. J Med Chem. 2024. PMID: 39231005
185 results