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Amelioration of a von Willebrand disease type 2B phenotype in vivo upon treatment with allele-selective siRNAs.
Linthorst NA, Jongejan YK, Dirven RJ, Laan SNJ, Bierings R, Casari C, Cordfunke RA, Dahlman JE, Dolezal N, Drijfhout JW, Leebeek FWG, Ruhaak LR, Schrader Echeverri E, Voorberg J, van Vlijmen BJM, Denis CV, Eikenboom JCJ. Linthorst NA, et al. Among authors: laan snj. Blood Adv. 2025 Jan 28;9(2):310-320. doi: 10.1182/bloodadvances.2024014601. Blood Adv. 2025. PMID: 39820471
Transcriptional and functional profiling identifies inflammation and endothelial-to-mesenchymal transition as potential drivers for phenotypic heterogeneity within a cohort of endothelial colony forming cells.
Laan SNJ, de Boer S, Dirven RJ, van Moort I, Kuipers TB, Mei H, Bierings R, Eikenboom J; SYMPHONY consortium. Laan SNJ, et al. J Thromb Haemost. 2024 Jul;22(7):2027-2038. doi: 10.1016/j.jtha.2024.03.018. Epub 2024 Apr 2. J Thromb Haemost. 2024. PMID: 38574861 Free article.