Yan X - Search Results

1

Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling of Erythroferrone in Anemic Rats with Chronic Kidney Disease and Chemotherapy-Induced Anemia: An Early Biomarker for Hemoglobin Response and rHuEPO Hyporesponsiveness.

Zhang L, Xu P, Yan X. Zhang L, et al. Among authors: yan x. ACS Pharmacol Transl Sci. 2024 Dec 11;8(1):189-202. doi: 10.1021/acsptsci.4c00575. eCollection 2025 Jan 10. ACS Pharmacol Transl Sci. 2024. PMID: 39816799

2

Dynamics of Erythroferrone Response to Erythropoietin in Rats.

Xu P, Wong RSM, Krzyzanski W, Yan X. Xu P, et al. Among authors: yan x. Front Pharmacol. 2022 Apr 20;13:876573. doi: 10.3389/fphar.2022.876573. eCollection 2022. Front Pharmacol. 2022. PMID: 35517793 Free PMC article.

3

Early erythroferrone levels can predict the long-term haemoglobin responses to erythropoiesis-stimulating agents.

Xu P, Wong RSM, Yan X. Xu P, et al. Among authors: yan x. Br J Pharmacol. 2024 Aug;181(16):2833-2850. doi: 10.1111/bph.16396. Epub 2024 Apr 23. Br J Pharmacol. 2024. PMID: 38653449

4

A Novel Combination Therapy of Erythropoietin and Thrombopoietin to Treat Erythropoietin-Resistance anemia.

Zou H, Xu P, Wong RSM, Yan X. Zou H, et al. Among authors: yan x. Pharm Res. 2022 Jun;39(6):1249-1265. doi: 10.1007/s11095-022-03304-z. Epub 2022 Jun 3. Pharm Res. 2022. PMID: 35661082

5

Clearance as an Early Indicator of Efficacy for Therapeutic Monoclonal Antibodies: Circumventing Dose Selection Challenges in Oncology.

Chen C, Fan X, Zhang L, Xu P, Zou H, Zhao X, Gupta M, Feng YS, Xu XS, Yan X. Chen C, et al. Among authors: yan x. Clin Pharmacokinet. 2023 May;62(5):705-713. doi: 10.1007/s40262-023-01231-9. Epub 2023 Mar 17. Clin Pharmacokinet. 2023. PMID: 36930421 Clinical Trial.

6

The Influence of Precursor Depletion and dose Regimens on Resistance to Erythropoiesis-Stimulating Agents: Insights from Simulations with Instantaneous Dose-Adaptation Algorithm.

Xu P, Wong RSM, Yan X. Xu P, et al. Among authors: yan x. J Pharm Sci. 2024 Jan;113(1):246-256. doi: 10.1016/j.xphs.2023.10.037. Epub 2023 Oct 31. J Pharm Sci. 2024. PMID: 37913904

7

Semi-mechanistic population pharmacokinetics analysis reveals distinct CYP2C19 dependency in the bioactivation of vicagrel and clopidogrel to active metabolite M15-2.

Zhang L, Sun H, Liu Y, Lai X, Gong Y, Liu X, Li YG, He Y, Zhang EY, Yan X. Zhang L, et al. Among authors: yan x. Eur J Pharm Sci. 2022 Oct 1;177:106264. doi: 10.1016/j.ejps.2022.106264. Epub 2022 Jul 20. Eur J Pharm Sci. 2022. PMID: 35868434 Free article.

8

Protein Binding and Population Pharmacokinetics of Dexmedetomidine after Prolonged Infusions in Adult Critically Ill Patients.

Yan X, Tse AHW, Lee A, Zhang L, Yang M, Zuo Z, Joynt GM. Yan X, et al. Clin Ther. 2021 Aug;43(8):1356-1369.e1. doi: 10.1016/j.clinthera.2021.06.004. Epub 2021 Jul 23. Clin Ther. 2021. PMID: 34304911

9

Novel Combination of Erythropoietin and Romiplostim to Treat Chemotherapy-Induced Anemia and Thrombocytopenia via Pharmacodynamic Interaction on Hematopoietic Stem and Progenitor Cells.

Fan X, Krzyzanski W, Wong RSM, Liu D, Yan X. Fan X, et al. Among authors: yan x. ACS Pharmacol Transl Sci. 2023 Nov 15;6(12):1884-1897. doi: 10.1021/acsptsci.3c00194. eCollection 2023 Dec 8. ACS Pharmacol Transl Sci. 2023. PMID: 38093847 Free PMC article.

10

Application of Pharmacokinetic-Pharmacodynamic Modeling in Drug Delivery: Development and Challenges.

Zou H, Banerjee P, Leung SSY, Yan X. Zou H, et al. Among authors: yan x. Front Pharmacol. 2020 Jul 3;11:997. doi: 10.3389/fphar.2020.00997. eCollection 2020. Front Pharmacol. 2020. PMID: 32719604 Free PMC article. Review.

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