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Catalytic-independent functions of the Integrator-PP2A complex (INTAC) confer sensitivity to BET inhibition.
Fan P, Shang XY, Song A, Chen S, Mao RY, Ma J, Chen J, Wang Z, Zheng H, Tao B, Hong L, Liu J, Xu W, Jiang W, Shen H, Zhang Q, Yang H, Meng XM, Lan F, Cheng J, Xu C, Zhang P, Jiang H, Chen FX. Fan P, et al. Among authors: meng xm. Nat Chem Biol. 2025 Jan 14. doi: 10.1038/s41589-024-01807-x. Online ahead of print. Nat Chem Biol. 2025. PMID: 39809894
SFN promotes renal fibrosis via binding with MYH9 in chronic kidney disease.
Wang F, Suo XG, Wang JN, Liu CY, Liu CC, Wang C, Li J, Duan ZH, Zhang FS, Xia YM, Jiang JJ, Hao YW, Li GY, Meng XM, Shao YX, Wang FC. Wang F, et al. Among authors: meng xm. Eur J Pharmacol. 2024 Sep 15;979:176806. doi: 10.1016/j.ejphar.2024.176806. Epub 2024 Jul 8. Eur J Pharmacol. 2024. PMID: 38986830 Free article.
Cpd-A1 alleviates acute kidney injury by inhibiting ferroptosis.
Chen Y, Wu MF, Xie MM, Lu Y, Li C, Xie SS, Ma WX, Ji ML, Hou R, Dong ZH, He RB, Zhang MM, Lu H, Gao L, Wen JG, Jin J, Dong XW, Che JX, Meng XM. Chen Y, et al. Among authors: meng xm. Acta Pharmacol Sin. 2024 Aug;45(8):1673-1685. doi: 10.1038/s41401-024-01277-w. Epub 2024 Apr 19. Acta Pharmacol Sin. 2024. PMID: 38641746
355 results