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Page 1
Enabling next-generation engineered TCR-T therapies based on high-throughput TCR discovery from diagnostic tumor biopsies.
Kuilman T, Schrikkema DS, Gadiot J, Gomez-Eerland R, Bies L, Walker J, Spaapen RM, Kok H, Houg D, Viyacheva M, Claassen YB, Saornil M, Krijgsman O, Stringer B, Ding H, Geleijnse A, Meinema AC, Weissbrich B, Lancee M, Engele CG, Sabatino M, Chen PL, Tsai KY, Mulé JJ, Sondak VK, van den Bulk J, de Miranda NF, Jedema I, Haanen JG, van Heijst JWJ, Schumacher TN, Linnemann C, Bendle GM. Kuilman T, et al. Among authors: van heijst jwj. Nat Commun. 2025 Jan 14;16(1):649. doi: 10.1038/s41467-024-55420-6. Nat Commun. 2025. PMID: 39809767 Free PMC article.
Mapping the life histories of T cells.
Schumacher TN, Gerlach C, van Heijst JW. Schumacher TN, et al. Nat Rev Immunol. 2010 Sep;10(9):621-31. doi: 10.1038/nri2822. Epub 2010 Aug 6. Nat Rev Immunol. 2010. PMID: 20689559 Review.
Long-term functionality of TCR-transduced T cells in vivo.
Coccoris M, Swart E, de Witte MA, van Heijst JW, Haanen JB, Schepers K, Schumacher TN. Coccoris M, et al. J Immunol. 2008 May 15;180(10):6536-43. doi: 10.4049/jimmunol.180.10.6536. J Immunol. 2008. PMID: 18453572
The descent of memory T cells.
Gerlach C, van Heijst JW, Schumacher TN. Gerlach C, et al. Ann N Y Acad Sci. 2011 Jan;1217:139-53. doi: 10.1111/j.1749-6632.2010.05830.x. Epub 2011 Jan 14. Ann N Y Acad Sci. 2011. PMID: 21251009 Review.
Dissecting T cell lineage relationships by cellular barcoding.
Schepers K, Swart E, van Heijst JW, Gerlach C, Castrucci M, Sie D, Heimerikx M, Velds A, Kerkhoven RM, Arens R, Schumacher TN. Schepers K, et al. J Exp Med. 2008 Sep 29;205(10):2309-18. doi: 10.1084/jem.20072462. Epub 2008 Sep 22. J Exp Med. 2008. PMID: 18809713 Free PMC article.
One naive T cell, multiple fates in CD8+ T cell differentiation.
Gerlach C, van Heijst JW, Swart E, Sie D, Armstrong N, Kerkhoven RM, Zehn D, Bevan MJ, Schepers K, Schumacher TN. Gerlach C, et al. J Exp Med. 2010 Jun 7;207(6):1235-46. doi: 10.1084/jem.20091175. Epub 2010 May 17. J Exp Med. 2010. PMID: 20479114 Free PMC article.
Heterogeneous differentiation patterns of individual CD8+ T cells.
Gerlach C, Rohr JC, Perié L, van Rooij N, van Heijst JW, Velds A, Urbanus J, Naik SH, Jacobs H, Beltman JB, de Boer RJ, Schumacher TN. Gerlach C, et al. Science. 2013 May 3;340(6132):635-9. doi: 10.1126/science.1235487. Epub 2013 Mar 14. Science. 2013. PMID: 23493421
25 results