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Acceptability of a dapivirine levonorgestrel vaginal ring in two Phase 1 trials (MTN-030/IPM 041 and MTN-044/IPM 053/CCN019): Implications for multipurpose prevention technology development.
Friedland BA, Gundacker H, Achilles SL, Chen BA, Hoesley C, Richardson BA, Kelly CW, Piper J, Johnson S, Devlin B, Steytler J, Kleinbeck K, Dangi B, Friend C, Song M, Mensch B, van der Straten A, Jacobson C, Hendrix CW, Brown J, Blithe D, Hiller SL; MTN-030/IPM 041 and MTN-044/IPM 053/CCN019 Protocol Teams for the Microbicide Trials Network and the Contraceptive Clinical Trials Network. Friedland BA, et al. Among authors: hoesley c. PLoS One. 2025 Jan 14;20(1):e0312957. doi: 10.1371/journal.pone.0312957. eCollection 2025. PLoS One. 2025. PMID: 39808648 Free PMC article. Clinical Trial.
Phase I Dose Volume Escalation of Rectally Administered PC-1005 to Assess Safety, Pharmacokinetics, and Antiviral Pharmacodynamics as a Multipurpose Prevention Technology (MTN-037).
Ho K, Hoesley C, Anderson PL, Fernández-Romero JA, Friedland BA, Kelly CW, Jiao Y, Edick S, Brand R, Kunjara Na Ayudhya RP, Zyhowski A, Hartman DJ, Reddy NB, Al-Khouja A, Piper J, Bauermeister JA, Teleshova N, Melo C, Cornejal N, Barnable P, Singh D, Scheckter R, McClure T, Hillier SL, Hendrix CW; MTN-037 Study Team. Ho K, et al. Among authors: hoesley c. J Acquir Immune Defic Syndr. 2024 Dec 1;97(4):379-386. doi: 10.1097/QAI.0000000000003506. J Acquir Immune Defic Syndr. 2024. PMID: 39808074 Clinical Trial.
Phase 1 randomized trials to assess safety, pharmacokinetics, and vaginal bleeding associated with use of extended duration dapivirine and levonorgestrel vaginal rings.
Achilles SL, Kelly CW, Hoesley CJ, Blithe DL, Brown J, Richardson BA, Devlin B, Hendrix CW, Poloyac SM, Marzinke MA, Gundacker H, Singh D, Piper JM, Johnson S, Steytler J, Chen BA; MTN-030/IPM 041 and MTN-044/IPM 053/CCN019 Protocol Teams for the Microbicide Trials Network and the Contraceptive Clinical Trials Network. Achilles SL, et al. Among authors: hoesley cj. PLoS One. 2024 Jun 5;19(6):e0304552. doi: 10.1371/journal.pone.0304552. eCollection 2024. PLoS One. 2024. PMID: 38838028 Free PMC article. Clinical Trial.
History of Rectal Product Use and Country of Residence Influence Preference for Rectal Microbicide Dosage Forms Among Young Sexual and Gender Minorities: A Multi-country Trial Comparing Placebo Douche, Suppository, and Insert Products.
Giguere R, Balán IC, Kutner BA, Choi SK, Tingler R, Johnson S, Macagna N, Webster J, Liu A, Chariyalertsak S, Hoesley C, Gonzales P, Ho K, Kayange N, Palanee-Phillips T, Brown E, Zemanek J, Jacobson CE, Doncel GF, Piper J, Bauermeister JA; MTN-035 Protocol Team. Giguere R, et al. Among authors: hoesley c. AIDS Behav. 2024 Aug;28(8):2577-2589. doi: 10.1007/s10461-024-04360-9. Epub 2024 May 13. AIDS Behav. 2024. PMID: 38740628 Clinical Trial.
A Phase 1 Clinical Trial to Assess the Safety and Pharmacokinetics of a Tenofovir Alafenamide/Elvitegravir Insert Administered Rectally for HIV Prevention.
Riddler SA, Kelly CW, Hoesley CJ, Ho KS, Piper JM, Edick S, Heard F, Doncel GF, Johnson S, Anderson PL, Brand RM, Kunjara Na Ayudhya RP, Bauermeister JA, Hillier SL, Hendrix CW. Riddler SA, et al. Among authors: hoesley cj. J Infect Dis. 2024 Sep 23;230(3):696-705. doi: 10.1093/infdis/jiae211. J Infect Dis. 2024. PMID: 38655842 Clinical Trial.
A conjoint experiment of three placebo rectal products used with receptive anal sex: results from MTN-035.
Bauermeister J, Lin W, Tingler R, Liu A, Chariyalertsak S, Hoesley C, Gonzales P, Ho K, Kayange N, Phillips TP, Johnson S, Brown E, Zemanek J, Jacobson CE, Doncel GF, Piper J; MTN-035 Protocol Team for the Microbicide Trials Network. Bauermeister J, et al. Among authors: hoesley c. J Int AIDS Soc. 2024 Mar;27(3):e26219. doi: 10.1002/jia2.26219. J Int AIDS Soc. 2024. PMID: 38494656 Free PMC article. Clinical Trial.
Phase 1 randomized pharmacokinetic and safety study of a 90-day tenofovir vaginal ring in the United States.
Liu AY, Gundacker H, Richardson B, Chen BA, Hoesley C, van der Straten A, Brown A, Beamer M, Robinson J, Jacobson CE, Scheckter R, Bunge K, Schwartz J, Thurman A, Piper JM, Marzinke MA; MTN-038 Protocol Team for the Microbicide Trials Network. Liu AY, et al. Among authors: hoesley c. J Int AIDS Soc. 2024 Mar;27(3):e26223. doi: 10.1002/jia2.26223. J Int AIDS Soc. 2024. PMID: 38444118 Free PMC article. Clinical Trial.
A latent trajectory analysis of young sexual and gender minorities' adherence to three rectal microbicide placebo formulations (MTN-035; a randomized crossover trial).
Choi SK, Bauermeister J, Tingler RC, Johnson S, Macagna N, Ho K, Hoesley C, Liu A, Kayange N, Palanee-Phillips T, Chariyalertsak S, Gonzales P, Piper JM; MTN-035 Protocol Team. Choi SK, et al. Among authors: hoesley c. BMC Public Health. 2023 Dec 8;23(1):2464. doi: 10.1186/s12889-023-17368-y. BMC Public Health. 2023. PMID: 38066471 Free PMC article. Clinical Trial.
A randomized trial of safety, acceptability and adherence of three rectal microbicide placebo formulations among young sexual and gender minorities who engage in receptive anal intercourse (MTN-035).
Bauermeister JA, Dominguez Islas C, Jiao Y, Tingler R, Brown E, Zemanek J, Giguere R, Balan I, Johnson S, Macagna N, Lucas J, Rose M, Jacobson C, Collins C, Livant E, Singh D, Ho K, Hoesley C, Liu A, Kayange N, Palanee-Phillips T, Chariyalertsak S, Gonzales P, Piper J; MTN-035 Protocol Team. Bauermeister JA, et al. Among authors: hoesley c. PLoS One. 2023 Apr 12;18(4):e0284339. doi: 10.1371/journal.pone.0284339. eCollection 2023. PLoS One. 2023. PMID: 37043527 Free PMC article. Clinical Trial.
63 results