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Page 1
Decoding brain structure to stage Alzheimer's disease pathology in Down syndrome.
Kennedy JT, Wisch JK, Dincer A, Roman J, Gordon BA, Handen B, Benzinger TLS, Head E, Mapstone M, Christian BT, Tudorascu DL, Laymon CL, Hartley SL, Lao P, Brickman AM, Zaman SH, Ances BM; ABC‐DS and DIAN Consortia. Kennedy JT, et al. Among authors: zaman sh. Alzheimers Dement. 2025 Jan 14:e14519. doi: 10.1002/alz.14519. Online ahead of print. Alzheimers Dement. 2025. PMID: 39807622
Further understanding the connection between Alzheimer's disease and Down syndrome.
Snyder HM, Bain LJ, Brickman AM, Carrillo MC, Esbensen AJ, Espinosa JM, Fernandez F, Fortea J, Hartley SL, Head E, Hendrix J, Kishnani PS, Lai F, Lao P, Lemere C, Mobley W, Mufson EJ, Potter H, Zaman SH, Granholm AC, Rosas HD, Strydom A, Whitten MS, Rafii MS. Snyder HM, et al. Among authors: zaman sh. Alzheimers Dement. 2020 Jul;16(7):1065-1077. doi: 10.1002/alz.12112. Epub 2020 Jun 16. Alzheimers Dement. 2020. PMID: 32544310 Free PMC article. Review.
The Alzheimer's Biomarker Consortium-Down Syndrome: Rationale and methodology.
Handen BL, Lott IT, Christian BT, Schupf N, OBryant S, Mapstone M, Fagan AM, Lee JH, Tudorascu D, Wang MC, Head E, Klunk W, Ances B, Lai F, Zaman S, Krinsky-McHale S, Brickman AM, Rosas HD, Cohen A, Andrews H, Hartley S, Silverman W; Alzheimer's Biomarker Consortium‐Down Syndrome (ABC‐DS). Handen BL, et al. Alzheimers Dement (Amst). 2020 Aug 3;12(1):e12065. doi: 10.1002/dad2.12065. eCollection 2020. Alzheimers Dement (Amst). 2020. PMID: 32775597 Free PMC article. Review.
The AT(N) framework for Alzheimer's disease in adults with Down syndrome.
Rafii MS, Ances BM, Schupf N, Krinsky-McHale SJ, Mapstone M, Silverman W, Lott I, Klunk W, Head E, Christian B, Lai F, Rosas HD, Zaman S, Petersen ME, Strydom A, Fortea J, Handen B, O'Bryant S. Rafii MS, et al. Alzheimers Dement (Amst). 2020 Oct 27;12(1):e12062. doi: 10.1002/dad2.12062. eCollection 2020. Alzheimers Dement (Amst). 2020. PMID: 33134477 Free PMC article.
Patterns of glucose hypometabolism in Down syndrome resemble sporadic Alzheimer's disease except for the putamen.
Zammit MD, Laymon CM, Tudorascu DL, Hartley SL, Piro-Gambetti B, Johnson SC, Stone CK, Mathis CA, Zaman SH, Klunk WE, Handen BL, Cohen AD, Christian BT. Zammit MD, et al. Among authors: zaman sh. Alzheimers Dement (Amst). 2021 Jan 13;12(1):e12138. doi: 10.1002/dad2.12138. eCollection 2020. Alzheimers Dement (Amst). 2021. PMID: 33490360 Free PMC article.
Role of tau deposition in early cognitive decline in Down syndrome.
Hartley SL, Handen BL, Tudorascu D, Lee L, Cohen A, Piro-Gambetti B, Zammit M, Klunk W, Laymon C, Zaman S, Ances BM, Sabbagh M, Christian BT. Hartley SL, et al. Alzheimers Dement (Amst). 2022 Apr 1;14(1):e12256. doi: 10.1002/dad2.12256. eCollection 2022. Alzheimers Dement (Amst). 2022. PMID: 35386473 Free PMC article.
Joint-label fusion brain atlases for dementia research in Down syndrome.
Queder N, Phelan MJ, Taylor L, Tustison N, Doran E, Hom C, Nguyen D, Lai F, Pulsifer M, Price J, Kreisl WC, Rosas HD, Krinsky-McHale S, Brickman AM, Yassa MA, Schupf N, Silverman W, Lott IT, Head E, Mapstone M, Keator DB; Alzheimer's Biomarkers Consortium. Queder N, et al. Alzheimers Dement (Amst). 2022 May 25;14(1):e12324. doi: 10.1002/dad2.12324. eCollection 2022. Alzheimers Dement (Amst). 2022. PMID: 35634535 Free PMC article.
Weight Loss and Alzheimer's Disease in Down Syndrome.
Fleming V, Helsel BC, Ptomey LT, Rosas HD, Handen B, Laymon C, Christian BT, Head E, Mapstone M, Lai F, Krinsky-McHale S, Zaman S, Ances BM, Lee JH, Hartley SL; Alzheimer’s Biomarker Consortium –Down Syndrome (ABC-DS) Consortium. Fleming V, et al. J Alzheimers Dis. 2023;91(3):1215-1227. doi: 10.3233/JAD-220865. J Alzheimers Dis. 2023. PMID: 36565120 Free PMC article.
Timing of Alzheimer's Disease by Intellectual Disability Level in Down Syndrome.
Hartley SL, Fleming V, Schworer EK, Peven J, Handen BL, Krinsky-McHale S, Hom C, Lee L, Tudorascu DL, Laymon C, Minhas D, Luo W, Cohen A, Zaman S, Ances BM, Mapstone M, Head E, Lai F, Rosas HD, Klunk W, Christian B; Alzheimer Biomarker Consortium-Down Syndrome. Hartley SL, et al. J Alzheimers Dis. 2023;95(1):213-225. doi: 10.3233/JAD-230200. J Alzheimers Dis. 2023. PMID: 37482997 Free PMC article.
93 results