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Clinical-grade extracellular vesicles derived from umbilical cord mesenchymal stromal cells: preclinical development and first-in-human intra-articular validation as therapeutics for knee osteoarthritis.
Figueroa-Valdés AI, Luz-Crawford P, Herrera-Luna Y, Georges-Calderón N, García C, Tobar HE, Araya MJ, Matas J, Donoso-Meneses D, de la Fuente C, Cuenca J, Parra E, Lillo F, Varela C, Cádiz MI, Vernal R, Ortloff A, Nardocci G, Castañeda V, Adasme-Vidal C, Kunze-Küllmer M, Hidalgo Y, Espinoza F, Khoury M, Alcayaga-Miranda F. Figueroa-Valdés AI, et al. Among authors: hidalgo y. J Nanobiotechnology. 2025 Jan 13;23(1):13. doi: 10.1186/s12951-024-03088-x. J Nanobiotechnology. 2025. PMID: 39806427 Free article.
Safety and efficacy of mesenchymal stromal cells mitochondria transplantation as a cell-free therapy for osteoarthritis.
Vega-Letter AM, García-Guerrero C, Yantén-Fuentes L, Pradenas C, Herrera-Luna Y, Lara-Barba E, Bustamante-Barrientos FA, Rojas M, Araya MJ, Jeraldo N, Aros C, Troncoso F, Poblete D, Court A, Ortloff A, Barraza J, Velarde F, Farkas C, Carril C, Luque-Campos N, Almarza G, Barahona M, Matas J, Cereceda L, Lorca R, Toledo J, Oyarce K, Vernal R, Caicedo A, Del Campo A, Hidalgo Y, Elizondo-Vega R, Djouad F, Khoury M, Figueroa FE, Luz-Crawford P. Vega-Letter AM, et al. Among authors: hidalgo y. J Transl Med. 2025 Jan 7;23(1):26. doi: 10.1186/s12967-024-05945-7. J Transl Med. 2025. PMID: 39773289 Free PMC article.
Mitochondrial division inhibitor (mdivi-1) induces extracellular matrix (ECM)-detachment of viable breast cancer cells by a DRP1-independent mechanism.
Silva-Pavez E, Mendoza E, Morgado-Cáceres P, Ahumada-Castro U, Bustos G, Kangme-Encalada M, de Arbina AL, Puebla-Huerta A, Muñoz F, Cereceda L, Varas-Godoy M, Hidalgo Y, Cardenas JC. Silva-Pavez E, et al. Among authors: hidalgo y. Sci Rep. 2024 Jun 19;14(1):14178. doi: 10.1038/s41598-024-64228-9. Sci Rep. 2024. PMID: 38898058 Free PMC article.
Levels of Small Extracellular Vesicles Containing hERG-1 and Hsp47 as Potential Biomarkers for Cardiovascular Diseases.
Osorio LA, Lozano M, Soto P, Moreno-Hidalgo V, Arévalo-Gil A, Ramírez-Balaguera A, Hevia D, Cifuentes J, Hidalgo Y, Alcayaga-Miranda F, Pasten C, Morales D, Varela D, Urquidi C, Iturriaga A, Rivera-Palma A, Larrea-Gómez R, Irarrázabal CE. Osorio LA, et al. Among authors: hidalgo y. Int J Mol Sci. 2024 Apr 30;25(9):4913. doi: 10.3390/ijms25094913. Int J Mol Sci. 2024. PMID: 38732154 Free PMC article.
A Phase I Dose-Escalation Clinical Trial to Assess the Safety and Efficacy of Umbilical Cord-Derived Mesenchymal Stromal Cells in Knee Osteoarthritis.
Matas J, García C, Poblete D, Vernal R, Ortloff A, Luque-Campos N, Hidalgo Y, Cuenca J, Infante C, Cadiz MI, Khoury M, Luz-Crawford P, Espinoza F. Matas J, et al. Among authors: hidalgo y. Stem Cells Transl Med. 2024 Mar 15;13(3):193-203. doi: 10.1093/stcltm/szad088. Stem Cells Transl Med. 2024. PMID: 38366909 Free PMC article. Clinical Trial.
Egocentric sexual network analysis among gay and bisexual men who have sex with men with and without mpox infection.
Sönmez İ, Martínez Riveros H, Folch C, Suñer C, Díaz Y, Alonso L, Agusti C, Mendoza A, Tarín-Vicente EJ, Oller X, Alemany A, Rivero À, Orviz E, Silva-Klug A, Mitjà O, Casabona J; MOVIE-CC Study Group. Sönmez İ, et al. Sex Transm Infect. 2023 Dec;99(8):541-547. doi: 10.1136/sextrans-2023-055901. Epub 2023 Sep 13. Sex Transm Infect. 2023. PMID: 37704363
Safety and efficacy of clinical-grade, cryopreserved menstrual blood mesenchymal stromal cells in experimental acute respiratory distress syndrome.
Alcayaga-Miranda F, Dutra Silva J, Parada N, Andrade da Silva LH, Ferreira Cruz F, Utreras Y, Hidalgo Y, Cádiz MI, Tapia Limonchi R, Espinoza F, Bruhn A, Khoury M, R M Rocco P, Cuenca J. Alcayaga-Miranda F, et al. Among authors: hidalgo y. Front Cell Dev Biol. 2023 Jan 30;11:1031331. doi: 10.3389/fcell.2023.1031331. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 36793446 Free PMC article.
Evaluating the Accuracy of Self-Collected Swabs for the Diagnosis of Mpox.
Ubals M, Tarín-Vicente EJ, Oller X, Mendoza A, Alemany A, Hernández-Rodríguez Á, Casañ C, Rivero Á, Coll P, Cabrera JM, Vall M, Agud-Dios M, Gil-Cruz E, Paris de Leon A, Marinero AR, Folgueira MD, Meléndez MÁ, Buhiichyk V, Galván-Casas C, Paredes R, Prat N, Sala Farré MR, Bonet-Simó JM, Ortiz-Romero PL, Clotet B, Cardona PJ, Blanco I, Marks M, Suñer C, Mitjà O; Movie Group. Ubals M, et al. Clin Infect Dis. 2023 Apr 3;76(7):1311-1314. doi: 10.1093/cid/ciac889. Clin Infect Dis. 2023. PMID: 36370091
35 results