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Effect of cardiomyocyte-specific lipid phosphate phosphatase 3 overexpression on high-fat diet-induced cardiometabolic dysfunction in mice.
Jose A, Pakkiriswami S, Mercer A, Paudel Y, Yi E, Fernando J, Pulinilkunnil T, Kienesberger PC. Jose A, et al. Among authors: kienesberger pc. Am J Physiol Heart Circ Physiol. 2025 Feb 1;328(2):H333-H347. doi: 10.1152/ajpheart.00518.2024. Epub 2025 Jan 13. Am J Physiol Heart Circ Physiol. 2025. PMID: 39805037 Free article.
Loss of function of transcription factor EB remodels lipid metabolism and cell death pathways in the cardiomyocyte.
Trivedi PC, Bartlett JJ, Mercer A, Slade L, Surette M, Ballabio A, Flibotte S, Hussein B, Rodrigues B, Kienesberger PC, Pulinilkunnil T. Trivedi PC, et al. Biochim Biophys Acta Mol Basis Dis. 2020 Oct 1;1866(10):165832. doi: 10.1016/j.bbadis.2020.165832. Epub 2020 May 8. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 32437957 Free article.
Lysophosphatidic acid metabolism and signaling in heart disease.
Jose A, Fernando JJ, Kienesberger PC. Jose A, et al. Among authors: kienesberger pc. Can J Physiol Pharmacol. 2024 Dec 1;102(12):685-696. doi: 10.1139/cjpp-2024-0077. Epub 2024 Jul 5. Can J Physiol Pharmacol. 2024. PMID: 38968609 Free article. Review.
Branched-chain ketoacid overload inhibits insulin action in the muscle.
Biswas D, Dao KT, Mercer A, Cowie AM, Duffley L, El Hiani Y, Kienesberger PC, Pulinilkunnil T. Biswas D, et al. J Biol Chem. 2020 Nov 13;295(46):15597-15621. doi: 10.1074/jbc.RA120.013121. Epub 2020 Sep 2. J Biol Chem. 2020. PMID: 32878988 Free PMC article.
Inhibiting BCKDK in triple negative breast cancer suppresses protein translation, impairs mitochondrial function, and potentiates doxorubicin cytotoxicity.
Biswas D, Slade L, Duffley L, Mueller N, Dao KT, Mercer A, Pakkiriswami S, El Hiani Y, Kienesberger PC, Pulinilkunnil T. Biswas D, et al. Among authors: kienesberger pc. Cell Death Discov. 2021 Sep 15;7(1):241. doi: 10.1038/s41420-021-00602-0. Cell Death Discov. 2021. PMID: 34526485 Free PMC article.
54 results