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Page 1
Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines.
Wei SC, Cantor AJ, Walleshauser J, Mepani R, Melton K, Bans A, Khekare P, Gupta S, Wang J, Soares C, Kiwan R, Lee J, McCawley S, Jani V, Leong WI, Shahi PK, Chan J, Boivin P, Otoupal P, Pattnaik BR, Gamm DM, Saha K, Gowen BG, Haak-Frendscho M, Janatpour MJ, Silverman AP. Wei SC, et al. bioRxiv [Preprint]. 2024 Dec 30:2024.12.30.630799. doi: 10.1101/2024.12.30.630799. bioRxiv. 2024. PMID: 39803585 Free PMC article. Preprint.
Novel Naphthyridones Targeting Pannexin 1 for Colitis Management.
Hsueh WY, Wu YL, Weng MT, Liu SY, Santavanond JP, Liu YC, Lin CI, Lai CN, Lu YR, Hsu JY, Gao HY, Lee JC, Wei SC, Lyu PC, Poon IKH, Hsieh HP, Chiu YH. Hsueh WY, et al. Among authors: wei sc. Adv Sci (Weinh). 2024 Dec 30:e2411538. doi: 10.1002/advs.202411538. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 39739600
Guselkumab in patients with moderately to severely active ulcerative colitis (QUASAR): phase 3 double-blind, randomised, placebo-controlled induction and maintenance studies.
Rubin DT, Allegretti JR, Panés J, Shipitofsky N, Yarandi SS, Huang KG, Germinaro M, Wilson R, Zhang H, Johanns J, Feagan BG, Hisamatsu T, Lichtenstein GR, Bressler B, Peyrin-Biroulet L, Sands BE, Dignass A; QUASAR Study Group. Rubin DT, et al. Lancet. 2025 Jan 4;405(10472):33-49. doi: 10.1016/S0140-6736(24)01927-5. Epub 2024 Dec 17. Lancet. 2025. PMID: 39706209 Clinical Trial.
Clinical Characteristics, Management, and Outcomes of Colitis-Associated Colorectal Cancer and the Comparison With Sporadic Colorectal Cancer in Taiwan.
Wu HY, Weng MT, Chou JW, Yen HH, Lin CC, Chiang FF, Chung CS, Lin WC, Chang CW, Le PH, Kuo CJ, Lin CP, Hsu WH, Chuang CH, Tsai TJ, Feng IC, Wei SC, Huang TY. Wu HY, et al. Among authors: wei sc. Clin Transl Gastroenterol. 2024 Dec 5. doi: 10.14309/ctg.0000000000000798. Online ahead of print. Clin Transl Gastroenterol. 2024. PMID: 39636008
Optimizing 5-aminosalicylate for moderate ulcerative colitis: expert recommendations from the Asia-Pacific, Middle East, and Africa Inflammatory Bowel Disease Coalition.
Akyüz F, An YK, Begun J, Aniwan S, Bui HH, Chan W, Choi CH, Chopdat N, Connor SJ, Desai D, Flanagan E, Kobayashi T, Lai AY, Leong RW, Leow AH, Leung WK, Limsrivilai J, Muzellina VN, Peddi K, Ran Z, Wei SC, Sollano J, Teo MMH, Wu K, Ye BD, Ooi CJ. Akyüz F, et al. Among authors: wei sc. Intest Res. 2024 Nov 4. doi: 10.5217/ir.2024.00089. Online ahead of print. Intest Res. 2024. PMID: 39492666 Free article. Review.
Noninvasive, microbiome-based diagnosis of inflammatory bowel disease.
Zheng J, Sun Q, Zhang M, Liu C, Su Q, Zhang L, Xu Z, Lu W, Ching J, Tang W, Cheung CP, Hamilton AL, Wilson O'Brien AL, Wei SC, Bernstein CN, Rubin DT, Chang EB, Morrison M, Kamm MA, Chan FKL, Zhang J, Ng SC. Zheng J, et al. Among authors: wei sc. Nat Med. 2024 Dec;30(12):3555-3567. doi: 10.1038/s41591-024-03280-4. Epub 2024 Oct 4. Nat Med. 2024. PMID: 39367251 Free PMC article.
Identification of a Guide RNA Targeting an Ultraconserved Element for Evaluation of Cas9 Genome Editors Across Mammalian Species.
Gowen BG, Khekare P, McCawley SR, Melton K, Soares C, Chan J, Jani V, Boivin P, Bans A, Leong WI, Cantor AJ, Walleshauser J, Otoupal PB, Mepani RJ, Silverman AP, Haak-Frendscho M, Wei SC. Gowen BG, et al. Among authors: wei sc. CRISPR J. 2024 Dec;7(6):306-309. doi: 10.1089/crispr.2024.0053. Epub 2024 Sep 23. CRISPR J. 2024. PMID: 39308435 No abstract available.
351 results