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Page 1
Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines.
Wei SC, Cantor AJ, Walleshauser J, Mepani R, Melton K, Bans A, Khekare P, Gupta S, Wang J, Soares C, Kiwan R, Lee J, McCawley S, Jani V, Leong WI, Shahi PK, Chan J, Boivin P, Otoupal P, Pattnaik BR, Gamm DM, Saha K, Gowen BG, Haak-Frendscho M, Janatpour MJ, Silverman AP. Wei SC, et al. Among authors: otoupal p. bioRxiv [Preprint]. 2024 Dec 30:2024.12.30.630799. doi: 10.1101/2024.12.30.630799. bioRxiv. 2024. PMID: 39803585 Free PMC article. Preprint.
Identification of a Guide RNA Targeting an Ultraconserved Element for Evaluation of Cas9 Genome Editors Across Mammalian Species.
Gowen BG, Khekare P, McCawley SR, Melton K, Soares C, Chan J, Jani V, Boivin P, Bans A, Leong WI, Cantor AJ, Walleshauser J, Otoupal PB, Mepani RJ, Silverman AP, Haak-Frendscho M, Wei SC. Gowen BG, et al. Among authors: otoupal pb. CRISPR J. 2024 Dec;7(6):306-309. doi: 10.1089/crispr.2024.0053. Epub 2024 Sep 23. CRISPR J. 2024. PMID: 39308435 No abstract available.
Engineering transcriptional regulation of pentose metabolism in Rhodosporidium toruloides for improved conversion of xylose to bioproducts.
Coradetti ST, Adamczyk PA, Liu D, Gao Y, Otoupal PB, Geiselman GM, Webb-Robertson BM, Burnet MC, Kim YM, Burnum-Johnson KE, Magnuson J, Gladden JM. Coradetti ST, et al. Among authors: otoupal pb. Microb Cell Fact. 2023 Aug 3;22(1):144. doi: 10.1186/s12934-023-02148-5. Microb Cell Fact. 2023. PMID: 37537586 Free PMC article.
Engineering Rhodosporidium toruloides for production of 3-hydroxypropionic acid from lignocellulosic hydrolysate.
Liu D, Hwang HJ, Otoupal PB, Geiselman GM, Kim J, Pomraning KR, Kim YM, Munoz N, Nicora CD, Gao Y, Burnum-Johnson KE, Jacobson O, Coradetti S, Kim J, Deng S, Dai Z, Prahl JP, Tanjore D, Lee TS, Magnuson JK, Gladden JM. Liu D, et al. Among authors: otoupal pb. Metab Eng. 2023 Jul;78:72-83. doi: 10.1016/j.ymben.2023.05.001. Epub 2023 May 16. Metab Eng. 2023. PMID: 37201565 Free article.
Advanced one-pot deconstruction and valorization of lignocellulosic biomass into triacetic acid lactone using Rhodosporidium toruloides.
Otoupal PB, Geiselman GM, Oka AM, Barcelos CA, Choudhary H, Dinh D, Zhong W, Hwang H, Keasling JD, Mukhopadhyay A, Sundstrom E, Haushalter RW, Sun N, Simmons BA, Gladden JM. Otoupal PB, et al. Microb Cell Fact. 2022 Dec 8;21(1):254. doi: 10.1186/s12934-022-01977-0. Microb Cell Fact. 2022. PMID: 36482295 Free PMC article.
Conversion of poplar biomass into high-energy density tricyclic sesquiterpene jet fuel blendstocks.
Geiselman GM, Kirby J, Landera A, Otoupal P, Papa G, Barcelos C, Sundstrom ER, Das L, Magurudeniya HD, Wehrs M, Rodriguez A, Simmons BA, Magnuson JK, Mukhopadhyay A, Lee TS, George A, Gladden JM. Geiselman GM, et al. Among authors: otoupal p. Microb Cell Fact. 2020 Nov 12;19(1):208. doi: 10.1186/s12934-020-01456-4. Microb Cell Fact. 2020. PMID: 33183275 Free PMC article.
33 results