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Developing novel Lin28 inhibitors by computer aided drug design.
Matias-Barrios VM, Radaeva M, Rosellinny G, Jia Q, Xie N, Villanueva M, Ibrahim H, Smith J, Gleave M, Lallous N, Straus SK, Cherkasov A, Dong X. Matias-Barrios VM, et al. Among authors: smith j. Cell Death Discov. 2025 Jan 12;11(1):5. doi: 10.1038/s41420-024-02281-z. Cell Death Discov. 2025. PMID: 39800739 Free PMC article.
Targeting SARS-CoV-2 papain-like protease in the postvaccine era.
Ton AT, Pandey M, Smith JR, Ban F, Fernandez M, Cherkasov A. Ton AT, et al. Trends Pharmacol Sci. 2022 Nov;43(11):906-919. doi: 10.1016/j.tips.2022.08.008. Epub 2022 Aug 24. Trends Pharmacol Sci. 2022. PMID: 36114026 Free PMC article. Review.
A novel class of broad-spectrum active-site-directed 3C-like protease inhibitors with nanomolar antiviral activity against highly immune-evasive SARS-CoV-2 Omicron subvariants.
Pérez-Vargas J, Worrall LJ, Olmstead AD, Ton AT, Lee J, Villanueva I, Thompson CAH, Dudek S, Ennis S, Smith JR, Shapira T, De Guzman J, Gang S, Ban F, Vuckovic M, Bielecki M, Kovacic S, Kenward C, Hong CY, Gordon DG, Levett PN, Krajden M, Leduc R, Boudreault PL, Niikura M, Paetzel M, Young RN, Cherkasov A, Strynadka NCJ, Jean F. Pérez-Vargas J, et al. Among authors: smith jr. Emerg Microbes Infect. 2023 Dec;12(2):2246594. doi: 10.1080/22221751.2023.2246594. Emerg Microbes Infect. 2023. PMID: 37555275 Free PMC article.
Pay-it-forward strategy reduced HPV vaccine delay and increased uptake among catch-up age girls: A randomized clinical trial.
Li J, Li Y, Qi C, He Y, Lu H, Xie Y, Ong JJ, Lu Y, Yang Y, Yang F, Du H, Gong W, Zou F, Larson HJ, Jit M, Lin L, Smith JS, Geng EH, Xu D, Tang W, Tang S, Tucker JD, Wu D. Li J, et al. Among authors: smith js. medRxiv [Preprint]. 2025 Jan 17:2025.01.16.25320655. doi: 10.1101/2025.01.16.25320655. medRxiv. 2025. PMID: 39867381 Free PMC article. Preprint.
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