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Examining the effect of direct-from-blood bacterial testing on antibiotic administration and clinical outcomes: a protocol and statistical analysis plan for a pragmatic randomised trial.
Gaston DC, Humphries RM, Lewis AA, Gatto CL, Wang L, Nelson GE, Stollings JL, Ereshefsky BJ, Christensen MA, Dear ML, Banerjee R, Miller KF, Self WH, Semler MW, Qian ET; Vanderbilt Center for Learning Healthcare. Gaston DC, et al. Among authors: wang l. BMJ Open. 2025 Jan 11;15(1):e090263. doi: 10.1136/bmjopen-2024-090263. BMJ Open. 2025. PMID: 39800394 Free PMC article.
Protocolized Post-Extubation Respiratory Support to prevent reintubation: protocol and statistical analysis plan for a clinical trial.
Casey JD, Vaughan ER, Lloyd BD, Bilas PA, Hall EJ, Toporek AH, Buell KG, Brown RM, Richardson RK, Rooks JC, Wang L, Lindsell CJ, Ely EW, Self WH, Bernard GR, Rice TW, Semler MW; Pragmatic Critical Care Research Group. Casey JD, et al. Among authors: wang l. BMJ Open. 2019 Aug 2;9(8):e030476. doi: 10.1136/bmjopen-2019-030476. BMJ Open. 2019. PMID: 31377713 Free PMC article.
Cognitive Outcomes in the Pragmatic Investigation of optimaL Oxygen Targets (CO-PILOT) trial: protocol and statistical analysis plan.
Mart MF, Semler MW, Bernard G, Casey JD, Ely EW, Freundlich R, Jackson JC, Kiehl A, Jenkins C, Wang G, Lindsell C, Bryant P, Rice TW, Self WH, Stollings J, Wanderer JP, Wang L, Han JH. Mart MF, et al. Among authors: wang g, wang l. BMJ Open. 2022 Nov 1;12(11):e064517. doi: 10.1136/bmjopen-2022-064517. BMJ Open. 2022. PMID: 36319061 Free PMC article.
Protocol and statistical analysis plan for the Antibiotic Choice On ReNal outcomes (ACORN) randomised clinical trial.
Qian ET, Casey JD, Wright A, Wang L, Siemann J, Dear ML, Stollings J, Lloyd BD, Seitz K, Nelson G, Wright P, Siew ED, Dennis B, Wrenn J, Andereck J, Self WH, Semler MW, Rice TW; Vanderbilt Learning Healthcare System Platform Investigators. Qian ET, et al. Among authors: wang l. BMJ Open. 2023 Mar 10;13(3):e066995. doi: 10.1136/bmjopen-2022-066995. BMJ Open. 2023. PMID: 36898748 Free PMC article.
Saline versus balanced crystalloids for intravenous fluid therapy in the emergency department: study protocol for a cluster-randomized, multiple-crossover trial.
Self WH, Semler MW, Wanderer JP, Ehrenfeld JM, Byrne DW, Wang L, Atchison L, Felbinger M, Jones ID, Russ S, Shaw AD, Bernard GR, Rice TW. Self WH, et al. Among authors: wang l. Trials. 2017 Apr 13;18(1):178. doi: 10.1186/s13063-017-1923-6. Trials. 2017. PMID: 28407811 Free PMC article. Clinical Trial.
Balanced Crystalloids versus Saline in Sepsis. A Secondary Analysis of the SMART Clinical Trial.
Brown RM, Wang L, Coston TD, Krishnan NI, Casey JD, Wanderer JP, Ehrenfeld JM, Byrne DW, Stollings JL, Siew ED, Bernard GR, Self WH, Rice TW, Semler MW. Brown RM, et al. Among authors: wang l. Am J Respir Crit Care Med. 2019 Dec 15;200(12):1487-1495. doi: 10.1164/rccm.201903-0557OC. Am J Respir Crit Care Med. 2019. PMID: 31454263 Free PMC article. Clinical Trial.
Protocol and statistical analysis plan for the PREventing cardiovascular collaPse with Administration of fluid REsuscitation during Induction and Intubation (PREPARE II) randomised clinical trial.
Russell DW, Casey JD, Gibbs KW, Dargin JM, Vonderhaar DJ, Joffe AM, Ghamande S, Khan A, Dutta S, Landsperger JS, Robison SW, Bentov I, Wozniak JM, Stempek S, White HD, Krol OF, Prekker ME, Driver BE, Brewer JM, Wang L, Lindsell CJ, Self WH, Rice TW, Semler MW, Janz D; PREPARE II Investigators. Russell DW, et al. Among authors: wang l. BMJ Open. 2020 Sep 18;10(9):e036671. doi: 10.1136/bmjopen-2019-036671. BMJ Open. 2020. PMID: 32948554 Free PMC article.
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