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Vaccine-induced T cell responses control Orthoflavivirus challenge infection without neutralizing antibodies in humans.
Kalimuddin S, Tham CYL, Chan YFZ, Hang SK, Kunasegaran K, Chia A, Chan CYY, Ng DHL, Sim JXY, Tan HC, Syenina A, Ngoh AQ, Hamis NZ, Chew V, Leong YS, Yee JX, Low JG, Chan KR, Ong EZ, Bertoletti A, Ooi EE. Kalimuddin S, et al. Among authors: ong ez. Nat Microbiol. 2025 Feb;10(2):374-387. doi: 10.1038/s41564-024-01903-7. Epub 2025 Jan 10. Nat Microbiol. 2025. PMID: 39794472 Free PMC article. Clinical Trial.
Therapeutic antibodies as a treatment option for dengue fever.
Chan KR, Ong EZ, Ooi EE. Chan KR, et al. Among authors: ong ez. Expert Rev Anti Infect Ther. 2013 Nov;11(11):1147-57. doi: 10.1586/14787210.2013.839941. Epub 2013 Oct 4. Expert Rev Anti Infect Ther. 2013. PMID: 24093625 Review.
Adverse effects following anti-COVID-19 vaccination with mRNA-based BNT162b2 are alleviated by altering the route of administration and correlate with baseline enrichment of T and NK cell genes.
Syenina A, Gan ES, Toh JZN, de Alwis R, Lin LZ, Tham CYL, Yee JX, Leong YS, Sam H, Cheong C, Teh YE, Wee ILE, Ng DHL, Chan KR, Sim JXY, Kalimuddin S, Ong EZ, Low JG, Ooi EE. Syenina A, et al. Among authors: ong ez. PLoS Biol. 2022 May 31;20(5):e3001643. doi: 10.1371/journal.pbio.3001643. eCollection 2022 May. PLoS Biol. 2022. PMID: 35639676 Free PMC article.
A phase I/II randomized, double-blinded, placebo-controlled trial of a self-amplifying Covid-19 mRNA vaccine.
Low JG, de Alwis R, Chen S, Kalimuddin S, Leong YS, Mah TKL, Yuen N, Tan HC, Zhang SL, Sim JXY, Chan YFZ, Syenina A, Yee JX, Ong EZ, Sekulovich R, Sullivan BB, Lindert K, Sullivan SM, Chivukula P, Hughes SG, Ooi EE. Low JG, et al. Among authors: ong ez. NPJ Vaccines. 2022 Dec 13;7(1):161. doi: 10.1038/s41541-022-00590-x. NPJ Vaccines. 2022. PMID: 36513697 Free PMC article.
36 results