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Page 1
Engineered Mycobacterium tuberculosis triple-kill-switch strain provides controlled tuberculosis infection in animal models.
Wang X, Su H, Wallach JB, Wagner JC, Braunecker BJ, Gardner M, Guinn KM, Howard NC, Klevorn T, Lin K, Liu YJ, Liu Y, Mugahid D, Rodgers M, Sixsmith J, Wakabayashi S, Zhu J, Zimmerman M, Dartois V, Flynn JL, Lin PL, Ehrt S, Fortune SM, Rubin EJ, Schnappinger D. Wang X, et al. Among authors: howard nc. Nat Microbiol. 2025 Jan 10. doi: 10.1038/s41564-024-01913-5. Online ahead of print. Nat Microbiol. 2025. PMID: 39794471
Paired analysis of host and pathogen genomes identifies determinants of human tuberculosis.
Luo Y, Huang CC, Howard NC, Wang X, Liu Q, Li X, Zhu J, Amariuta T, Asgari S, Ishigaki K, Calderon R, Raman S, Ramnarine AK, Mayfield JA, Moody DB, Lecca L, Fortune SM, Murray MB, Raychaudhuri S. Luo Y, et al. Among authors: howard nc. Nat Commun. 2024 Nov 29;15(1):10393. doi: 10.1038/s41467-024-54741-w. Nat Commun. 2024. PMID: 39613754 Free PMC article.
Vaginal lactobacilli produce anti-inflammatory β-carboline compounds.
Glick VJ, Webber CA, Simmons LE, Martin MC, Ahmad M, Kim CH, Adams AND, Bang S, Chao MC, Howard NC, Fortune SM, Verma M, Jost M, Beura LK, James MJ, Lee SY, Mitchell CM, Clardy J, Kim KH, Gopinath S. Glick VJ, et al. Among authors: howard nc. Cell Host Microbe. 2024 Nov 13;32(11):1897-1909.e7. doi: 10.1016/j.chom.2024.09.014. Epub 2024 Oct 17. Cell Host Microbe. 2024. PMID: 39423813
Identification of bacterial determinants of tuberculosis infection and treatment outcomes: a phenogenomic analysis of clinical strains.
Stanley S, Spaulding CN, Liu Q, Chase MR, Ha DTM, Thai PVK, Lan NH, Thu DDA, Quang NL, Brown J, Hicks ND, Wang X, Marin M, Howard NC, Vickers AJ, Karpinski WM, Chao MC, Farhat MR, Caws M, Dunstan SJ, Thuong NTT, Fortune SM. Stanley S, et al. Among authors: howard nc. Lancet Microbe. 2024 Jun;5(6):e570-e580. doi: 10.1016/S2666-5247(24)00022-3. Epub 2024 May 8. Lancet Microbe. 2024. PMID: 38734030 Free PMC article.
High-throughput phenogenotyping of Mycobacteria tuberculosis clinical strains reveals bacterial determinants of treatment outcomes.
Stanley S, Spaulding CN, Liu Q, Chase MR, Ha DTM, Thai PVK, Lan NH, Thu DDA, Quang NL, Brown J, Hicks ND, Wang X, Marin M, Howard NC, Vickers AJ, Karpinski WM, Chao MC, Farhat MR, Caws M, Dunstan SJ, Thuong NTT, Fortune SM. Stanley S, et al. Among authors: howard nc. bioRxiv [Preprint]. 2023 Apr 10:2023.04.09.536166. doi: 10.1101/2023.04.09.536166. bioRxiv. 2023. PMID: 37090677 Free PMC article. Preprint.
Publisher Correction: Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.
Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, Ulland TK, Darby M, Park E, Karim F, Melocchi L, Madansein R, Dullabh KJ, Dunlap M, Marin-Agudelo N, Ebihara T, Ndung'u T, Kaushal D, Pym AS, Kolls JK, Steyn A, Zúñiga J, Horsnell W, Yokoyama WM, Shalek AK, Kløverpris HN, Colonna M, Leslie A, Khader SA. Ardain A, et al. Among authors: howard nc. Nature. 2019 Aug;572(7768):E10. doi: 10.1038/s41586-019-1458-y. Nature. 2019. PMID: 31337923
Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis.
Ardain A, Domingo-Gonzalez R, Das S, Kazer SW, Howard NC, Singh A, Ahmed M, Nhamoyebonde S, Rangel-Moreno J, Ogongo P, Lu L, Ramsuran D, de la Luz Garcia-Hernandez M, K Ulland T, Darby M, Park E, Karim F, Melocchi L, Madansein R, Dullabh KJ, Dunlap M, Marin-Agudelo N, Ebihara T, Ndung'u T, Kaushal D, Pym AS, Kolls JK, Steyn A, Zúñiga J, Horsnell W, Yokoyama WM, Shalek AK, Kløverpris HN, Colonna M, Leslie A, Khader SA. Ardain A, et al. Among authors: howard nc. Nature. 2019 Jun;570(7762):528-532. doi: 10.1038/s41586-019-1276-2. Epub 2019 Jun 5. Nature. 2019. PMID: 31168092 Free PMC article.
12 results