Lei X - Search Results

1

Probing into the plasma stability and microsomal stability of thiol-based prodrug derivatives: Using IYS-15, an HDAC inhibitor as the model thiol.

Zhu L, Wang W, Li Q, Wang H, Lei X. Zhu L, et al. Among authors: lei x. Bioorg Med Chem. 2025 Jan 5;119:118064. doi: 10.1016/j.bmc.2025.118064. Online ahead of print. Bioorg Med Chem. 2025. PMID: 39793402

2

"One pot" synthesis of quinazolinone-[2,3]-fused polycyclic scaffolds in a three-step reaction sequence.

Zhang Y, Zhu L, Lu Y, Lei X, Li Y. Zhang Y, et al. Among authors: lei x. Org Biomol Chem. 2024 Jun 12;22(23):4720-4726. doi: 10.1039/d4ob00529e. Org Biomol Chem. 2024. PMID: 38775781

3

Construction of indolizine scaffolds from α,ω-alkynoic acids and α,ω-vinylamines via sequential-relay catalysis in "one pot".

Liu J, Lu Y, Zhu L, Lei X. Liu J, et al. Among authors: lei x. Org Biomol Chem. 2024 Mar 20;22(12):2474-2479. doi: 10.1039/d4ob00067f. Org Biomol Chem. 2024. PMID: 38440950

4

Synthesis, biological evaluation, and molecular modeling of ORM-10921 and its analogs as α_2C -adrenoceptor antagonists.

Ma Q, Zhu L, Zhang Z, Xiong Y, Li Y, Lei X. Ma Q, et al. Among authors: lei x. Arch Pharm (Weinheim). 2023 Aug;356(8):e2300125. doi: 10.1002/ardp.202300125. Epub 2023 May 18. Arch Pharm (Weinheim). 2023. PMID: 37202522

5

A fluorine scan on the Zn²⁺-binding thiolate side chain of HDAC inhibitor largazole: Synthesis, biological evaluation, and molecular modeling.

Zhang B, Liu J, Gao D, Yu X, Wang J, Lei X. Zhang B, et al. Among authors: lei x. Eur J Med Chem. 2019 Nov 15;182:111672. doi: 10.1016/j.ejmech.2019.111672. Epub 2019 Sep 4. Eur J Med Chem. 2019. PMID: 31505452

6

Discovery, synthesis, biological evaluation and molecular docking study of (R)-5-methylmellein and its analogs as selective monoamine oxidase A inhibitors.

Huang C, Xiong J, Guan HD, Wang CH, Lei X, Hu JF. Huang C, et al. Among authors: lei x. Bioorg Med Chem. 2019 May 15;27(10):2027-2040. doi: 10.1016/j.bmc.2019.03.060. Epub 2019 Apr 2. Bioorg Med Chem. 2019. PMID: 30975503

7

Synthesis of the analogs of plocabulin and their preliminary structure-activity relationship study.

Wang L, Li X, Cui H, Lei X, Liu H, Wang Q, Li Y. Wang L, et al. Among authors: lei x. Bioorg Med Chem Lett. 2021 Nov 1;51:128355. doi: 10.1016/j.bmcl.2021.128355. Epub 2021 Sep 8. Bioorg Med Chem Lett. 2021. PMID: 34508844

8

Synthesis and biological evaluation of C-12' substituted vinflunine derivatives.

Lei XS, Yu XD, Yin L, Liu ZH, Tang PC. Lei XS, et al. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4602-5. doi: 10.1016/j.bmcl.2008.07.025. Epub 2008 Jul 12. Bioorg Med Chem Lett. 2008. PMID: 18653334

9

Corrigendum to "A fluorine scan on the Zn²⁺-binding thiolate side chain of HDAC inhibitor largazole: Synthesis, biological evaluation, and molecular modeling" [Eur. J. Med. Chem. 182 (2019) 111672].

Zhang B, Liu J, Gao D, Yu X, Wang J, Lei X. Zhang B, et al. Among authors: lei x. Eur J Med Chem. 2020 Jul 15;198:112340. doi: 10.1016/j.ejmech.2020.112340. Epub 2020 May 1. Eur J Med Chem. 2020. PMID: 32371332 No abstract available.

10

Identification and immunological evaluation of novel TLR2 agonists through structural optimization of Diprovocim.

Wang X, Wang Y, Zhu Y, Lei X, Zhang M, Li Y. Wang X, et al. Among authors: lei x. Eur J Med Chem. 2022 Dec 5;243:114771. doi: 10.1016/j.ejmech.2022.114771. Epub 2022 Sep 15. Eur J Med Chem. 2022. PMID: 36174413

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

4,965 results

Search Page

Filters