Wang H - Search Results

1

Computational-aided rational mutation design of pertuzumab to overcome active HER2 mutation S310F through antibody-drug conjugates.

Bai X, Xu L, Wang Z, Zhuang X, Ning J, Sun Y, Wang H, Guo Y, Xu Y, Guo J, Chen S, Pan L. Bai X, et al. Among authors: wang h, wang z. Proc Natl Acad Sci U S A. 2025 Jan 7;122(1):e2413686122. doi: 10.1073/pnas.2413686122. Epub 2024 Dec 30. Proc Natl Acad Sci U S A. 2025. PMID: 39793038

2

Site-specific PEGylation of a mutated-cysteine residue and its effect on tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL).

Pan LQ, Wang HB, Lai J, Xu YC, Zhang C, Chen SQ. Pan LQ, et al. Biomaterials. 2013 Dec;34(36):9115-23. doi: 10.1016/j.biomaterials.2013.08.020. Epub 2013 Aug 24. Biomaterials. 2013. PMID: 23981355

3

Novel conjugation of tumor-necrosis-factor-related apoptosis-inducing ligand (TRAIL) with monomethyl auristatin E for efficient antitumor drug delivery.

Pan LQ, Wang HB, Xie ZM, Li ZH, Tang XJ, Xu YC, Zhang C, Naranmandura H, Chen SQ. Pan LQ, et al. Among authors: wang hb. Adv Mater. 2013 Sep 14;25(34):4718-22. doi: 10.1002/adma.201301385. Epub 2013 Jul 12. Adv Mater. 2013. PMID: 23847045

4

Optimization strategies for expression of a novel bifunctional anti-PD-L1/TGFBR2-ECD fusion protein.

Gao ZZ, Li C, Chen G, Yuan JJ, Zhou YQ, Jiao JY, Nie L, Qi J, Yang Y, Chen SQ, Wang HB. Gao ZZ, et al. Protein Expr Purif. 2022 Jan;189:105973. doi: 10.1016/j.pep.2021.105973. Epub 2021 Sep 22. Protein Expr Purif. 2022. PMID: 34560256 Review.

5

BR109, a Novel Fully Humanized T-Cell-Engaging Bispecific Antibody with GPRC5D Binding, Has Potent Antitumor Activities in Multiple Myeloma.

Liu Y, Zhou YQ, Nie L, Zhu SS, Li N, Wu ZH, Wang Q, Qi J, Wu BY, Chen SQ, Wang HB. Liu Y, et al. Cancers (Basel). 2023 Dec 9;15(24):5774. doi: 10.3390/cancers15245774. Cancers (Basel). 2023. PMID: 38136320 Free PMC article.

6

Formation of protein sub-visible particles during vacuum degassing of etanercept solutions.

Wang H, Zheng HJ, Wang Z, Bai H, Carpenter JF, Chen S, Fang WJ. Wang H, et al. Among authors: wang z. Int J Biol Macromol. 2014 May;66:151-7. doi: 10.1016/j.ijbiomac.2014.02.001. Epub 2014 Feb 7. Int J Biol Macromol. 2014. PMID: 24513220

7

The effect of gene copy number and co-expression of chaperone on production of albumin fusion proteins in Pichia pastoris.

Shen Q, Wu M, Wang HB, Naranmandura H, Chen SQ. Shen Q, et al. Among authors: wang hb. Appl Microbiol Biotechnol. 2012 Nov;96(3):763-72. doi: 10.1007/s00253-012-4337-0. Epub 2012 Aug 12. Appl Microbiol Biotechnol. 2012. PMID: 22885695

8

Preclinical studies of targeted therapies for CD20-positive B lymphoid malignancies by Ofatumumab conjugated with auristatin.

Li ZH, Zhang Q, Wang HB, Zhang YN, Ding D, Pan LQ, Miao D, Xu S, Zhang C, Luo PH, Naranmandura H, Chen SQ. Li ZH, et al. Among authors: wang hb. Invest New Drugs. 2014 Feb;32(1):75-86. doi: 10.1007/s10637-013-9995-y. Epub 2013 Aug 1. Invest New Drugs. 2014. PMID: 23903896

9

An Underlying Cause and Solution to the Poor Size Exclusion Chromatography Performance of Antibody-Drug Conjugates.

Liu JZ, Du CY, Gao H, Wang H, Hu F, Fang WJ. Liu JZ, et al. Among authors: wang h. Pharm Res. 2024 Dec;41(12):2299-2317. doi: 10.1007/s11095-024-03796-x. Epub 2024 Dec 13. Pharm Res. 2024. PMID: 39673013

10

Preclinical characterization of the novel anti-SIRPα antibody BR105 that targets the myeloid immune checkpoint.

Wu ZH, Li N, Mei XF, Chen J, Wang XZ, Guo TT, Chen G, Nie L, Chen Y, Jiang MZ, Wang JT, Wang HB. Wu ZH, et al. J Immunother Cancer. 2022 Mar;10(3):e004054. doi: 10.1136/jitc-2021-004054. J Immunother Cancer. 2022. PMID: 35256517 Free PMC article.

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