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SIV Env RhmAbs + N-803 at ART initiation prolongs viral decay without disrupting reservoir establishment in SIV-infected infant macaques.
Farinre O, Anaya T, King AC, Endrias K, Hébert AH, Hill AL, Jean S, Wood JS, Ehnert S, Liang S, Laird GM, Mason RD, Roederer M, Safrit JT, Mavigner M, Chahroudi A. Farinre O, et al. Among authors: roederer m. PLoS Pathog. 2025 Jan 10;21(1):e1012863. doi: 10.1371/journal.ppat.1012863. eCollection 2025 Jan. PLoS Pathog. 2025. PMID: 39792949 Free PMC article.
Adeno-associated viral delivery of Env-specific antibodies prevents SIV rebound after discontinuing antiretroviral therapy.
Klenchin VA, Clark NM, Keles NK, Capuano S, Mason R, Gao G, Broman A, Kose E, Immonen TT, Fennessey CM, Keele BF, Lifson JD, Roederer M, Gardner MR, Evans DT. Klenchin VA, et al. Among authors: roederer m. bioRxiv [Preprint]. 2024 Jun 3:2024.05.30.593694. doi: 10.1101/2024.05.30.593694. bioRxiv. 2024. PMID: 38895320 Free PMC article. Preprint.
Isolation and structure of broad SIV-neutralizing antibodies reveal a proximal helical MPER epitope recognized by a rhesus multi-donor class.
Gorman J, Du R, Lai YT, Ahmadi MS, King HAD, Song K, Manalang K, Gonelli CA, Schramm CA, Cheng C, Nguyen R, Ambrozak D, Druz A, Shen CH, Yang Y, Douek DC, Kwong PD, Roederer M, Mason RD. Gorman J, et al. Among authors: roederer m. Cell Rep. 2025 Jan 28;44(1):115163. doi: 10.1016/j.celrep.2024.115163. Epub 2025 Jan 9. Cell Rep. 2025. PMID: 39792559 Free article.
Structural development of the HIV-1 apex-directed PGT145-PGDM1400 antibody lineage.
Mason RD, Zhang B, Morano NC, Shen CH, McKee K, Heimann A, Du R, Nazzari AF, Hodges S, Kanai T, Lin BC, Louder MK, Doria-Rose NA, Zhou T, Shapiro L, Roederer M, Kwong PD, Gorman J. Mason RD, et al. Among authors: roederer m. Cell Rep. 2025 Jan 28;44(1):115223. doi: 10.1016/j.celrep.2024.115223. Epub 2025 Jan 17. Cell Rep. 2025. PMID: 39826122 Free article.
Intravenous Bacillus Calmette-Guérin (BCG) Induces a More Potent Airway and Lung Immune Response than Intradermal BCG in Simian Immunodeficiency Virus-infected Macaques.
Jauro S, Larson EC, Gleim JL, Wahlberg BM, Rodgers MA, Chehab JC, Lopez-Velazques AE, Ameel CL, Tomko JA, Sakal JL, DeMarco T, Borish HJ, Maiello P, Potter EL, Roederer M, Ling Lin P, Flynn JL, Scanga CA. Jauro S, et al. Among authors: roederer m. J Immunol. 2024 Nov 1;213(9):1358-1370. doi: 10.4049/jimmunol.2400417. J Immunol. 2024. PMID: 39311665
Markov Field network model of multi-modal data predicts effects of immune system perturbations on intravenous BCG vaccination in macaques.
Wang S, Myers AJ, Irvine EB, Wang C, Maiello P, Rodgers MA, Tomko J, Kracinovsky K, Borish HJ, Chao MC, Mugahid D, Darrah PA, Seder RA, Roederer M, Scanga CA, Lin PL, Alter G, Fortune SM, Flynn JL, Lauffenburger DA. Wang S, et al. Among authors: roederer m. bioRxiv [Preprint]. 2024 Oct 30:2024.04.13.589359. doi: 10.1101/2024.04.13.589359. bioRxiv. 2024. Update in: Cell Syst. 2024 Dec 18;15(12):1278-1294.e4. doi: 10.1016/j.cels.2024.10.001. PMID: 39554028 Free PMC article. Updated. Preprint.
Markov field network model of multi-modal data predicts effects of immune system perturbations on intravenous BCG vaccination in macaques.
Wang S, Myers AJ, Irvine EB, Wang C, Maiello P, Rodgers MA, Tomko J, Kracinovsky K, Borish HJ, Chao MC, Mugahid D, Darrah PA, Seder RA, Roederer M, Scanga CA, Lin PL, Alter G, Fortune SM, Flynn JL, Lauffenburger DA. Wang S, et al. Among authors: roederer m. Cell Syst. 2024 Dec 18;15(12):1278-1294.e4. doi: 10.1016/j.cels.2024.10.001. Epub 2024 Nov 5. Cell Syst. 2024. PMID: 39504969 Free article.
Safety and immunogenicity of recombinant poxvirus HIV-1 vaccines in young adults on highly active antiretroviral therapy.
Greenough TC, Cunningham CK, Muresan P, McManus M, Persaud D, Fenton T, Barker P, Gaur A, Panicali D, Sullivan JL, Luzuriaga K; Pediatric AIDS Clinical Trials Group P1059 Team. Greenough TC, et al. Vaccine. 2008 Dec 9;26(52):6883-93. doi: 10.1016/j.vaccine.2008.09.084. Epub 2008 Oct 20. Vaccine. 2008. PMID: 18940219 Free PMC article. Clinical Trial.
SIV monoclonal antibody administration spanning treatment interruption in macaques delays viral rebound and selects escape variants.
King HAD, Brammer D, Lewitus E, Fennessey CM, Manalang KM, Shrader HR, Andrew S, Kuri P, Lind M, Pham P, Sanders-Buell E, Bai H, Mason R, Song K, McCarthy E, Helmold Hait S, Todd JP, Pegu A, Foulds KE, Lifson JD, Keele BF, Rolland M, Roederer M, Bolton DL. King HAD, et al. Among authors: roederer m. Proc Natl Acad Sci U S A. 2025 Feb 4;122(5):e2404767122. doi: 10.1073/pnas.2404767122. Epub 2025 Jan 30. Proc Natl Acad Sci U S A. 2025. PMID: 39883843
484 results