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Coenzyme Q10 deficiency disrupts lipid metabolism by altering cholesterol homeostasis in neurons.
Pesini A, Barriocanal-Casado E, Compagnoni GM, Hidalgo-Gutierrez A, Yanez G, Bakkali M, Chhonker YS, Kleiner G, Larrea D, Tadesse S, Lopez LC, Murry DJ, Di Fonzo A, Area-Gomez E, Quinzii CM. Pesini A, et al. Among authors: lopez lc. Free Radic Biol Med. 2025 Jan 7:S0891-5849(25)00009-7. doi: 10.1016/j.freeradbiomed.2025.01.009. Online ahead of print. Free Radic Biol Med. 2025. PMID: 39788391 Free article.
CoQ10 supplementation rescues nephrotic syndrome through normalization of H2S oxidation pathway.
Kleiner G, Barca E, Ziosi M, Emmanuele V, Xu Y, Hidalgo-Gutierrez A, Qiao C, Tadesse S, Area-Gomez E, Lopez LC, Quinzii CM. Kleiner G, et al. Among authors: lopez lc. Biochim Biophys Acta Mol Basis Dis. 2018 Nov;1864(11):3708-3722. doi: 10.1016/j.bbadis.2018.09.002. Epub 2018 Sep 6. Biochim Biophys Acta Mol Basis Dis. 2018. PMID: 30251690 Free PMC article.
Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism.
González-García P, Hidalgo-Gutiérrez A, Mascaraque C, Barriocanal-Casado E, Bakkali M, Ziosi M, Abdihankyzy UB, Sánchez-Hernández S, Escames G, Prokisch H, Martín F, Quinzii CM, López LC. González-García P, et al. Among authors: lopez lc. Hum Mol Genet. 2020 Nov 25;29(19):3296-3311. doi: 10.1093/hmg/ddaa214. Hum Mol Genet. 2020. PMID: 32975579 Free PMC article.
Metabolic Targets of Coenzyme Q10 in Mitochondria.
Hidalgo-Gutiérrez A, González-García P, Díaz-Casado ME, Barriocanal-Casado E, López-Herrador S, Quinzii CM, López LC. Hidalgo-Gutiérrez A, et al. Among authors: lopez herrador s, lopez lc. Antioxidants (Basel). 2021 Mar 26;10(4):520. doi: 10.3390/antiox10040520. Antioxidants (Basel). 2021. PMID: 33810539 Free PMC article. Review.
Whole-Exome Sequencing Study of Fibroblasts Derived From Patients With Cerebellar Ataxia Referred to Investigate CoQ10 Deficiency.
Monfrini E, Pesini A, Biella F, Sobreira CFR, Emmanuele V, Brescia G, Lopez LC, Tadesse S, Hirano M, Comi GP, Quinzii CM, Di Fonzo A. Monfrini E, et al. Among authors: lopez lc. Neurol Genet. 2023 Mar 14;9(2):e200058. doi: 10.1212/NXG.0000000000200058. eCollection 2023 Apr. Neurol Genet. 2023. PMID: 37090936 Free PMC article.
Heterogeneity of coenzyme Q10 deficiency: patient study and literature review.
Emmanuele V, López LC, Berardo A, Naini A, Tadesse S, Wen B, D'Agostino E, Solomon M, DiMauro S, Quinzii C, Hirano M. Emmanuele V, et al. Among authors: lopez lc. Arch Neurol. 2012 Aug;69(8):978-83. doi: 10.1001/archneurol.2012.206. Arch Neurol. 2012. PMID: 22490322 Free PMC article. Review.
Animal Models of Coenzyme Q Deficiency: Mechanistic and Translational Learnings.
González-García P, Barriocanal-Casado E, Díaz-Casado ME, López-Herrador S, Hidalgo-Gutiérrez A, López LC. González-García P, et al. Among authors: lopez herrador s, lopez lc. Antioxidants (Basel). 2021 Oct 26;10(11):1687. doi: 10.3390/antiox10111687. Antioxidants (Basel). 2021. PMID: 34829558 Free PMC article. Review.
173 results