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145 results

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Page 1
Formation of I2+III2 supercomplex rescues respiratory chain defects.
Liang C, Padavannil A, Zhang S, Beh S, Robinson DRL, Meisterknecht J, Cabrera-Orefice A, Koves TR, Watanabe C, Watanabe M, Illescas M, Lim R, Johnson JM, Ren S, Wu YJ, Kappei D, Ghelli AM, Funai K, Osaka H, Muoio D, Ugalde C, Wittig I, Stroud DA, Letts JA, Ho L. Liang C, et al. Among authors: muoio d. Cell Metab. 2025 Jan 8:S1550-4131(24)00457-1. doi: 10.1016/j.cmet.2024.11.011. Online ahead of print. Cell Metab. 2025. PMID: 39788125
Ketogenesis protects against MASLD-MASH progression through mechanisms that extend beyond overall fat oxidation rate.
Queathem ED, Stagg D, Nelson A, Chaves AB, Crown SB, Fulghum K, D Avignon DA, Ryder JR, Bolan PJ, Hayir A, Gillingham JR, Jannatpour S, Rome FI, Williams AS, Muoio DM, Ikramuddin S, Hughey CC, Puchalska P, Crawford PA. Queathem ED, et al. Among authors: muoio dm. bioRxiv [Preprint]. 2024 Dec 21:2024.10.17.618895. doi: 10.1101/2024.10.17.618895. bioRxiv. 2024. PMID: 39464122 Free PMC article. Preprint.
Direct mitochondrial import of lactate supports resilient carbohydrate oxidation.
Cluntun AA, Visker JR, Velasco-Silva JN, Lang MJ, Cedeño-Rosario L, Shankar TS, Hamouche R, Ling J, Kim JE, Toshniwal AG, Low HK, Cunningham CN, Carrington J, Catrow JL, Pearce Q, Jeong MY, Bott AJ, Narbona-Pérez ÁJ, Stanley CE, Li Q, Eberhardt DR, Morgan JT, Yadav T, Wells CE, Ramadurai DKA, Swiatek WI, Chaudhuri D, Rothstein JD, Muoio DM, Paulo JA, Gygi SP, Baker SA, Navankasattusas S, Cox JE, Funai K, Drakos SG, Rutter J, Ducker GS. Cluntun AA, et al. Among authors: muoio dm. bioRxiv [Preprint]. 2024 Oct 8:2024.10.07.617073. doi: 10.1101/2024.10.07.617073. bioRxiv. 2024. PMID: 39416192 Free PMC article. Preprint.
APOL1-mediated monovalent cation transport contributes to APOL1-mediated podocytopathy in kidney disease.
Datta S, Antonio BM, Zahler NH, Theile JW, Krafte D, Zhang H, Rosenberg PB, Chaves AB, Muoio DM, Zhang G, Silas D, Li G, Soldano K, Nystrom S, Ferreira D, Miller SE, Bain JR, Muehlbauer MJ, Ilkayeva O, Becker TC, Hohmeier HE, Newgard CB, Olabisi OA. Datta S, et al. Among authors: muoio dm. J Clin Invest. 2024 Jan 16;134(5):e172262. doi: 10.1172/JCI172262. J Clin Invest. 2024. PMID: 38227370 Free PMC article.
Challenges and opportunities in targeting metabolism.
Birsoy K, Chandel NS, Fendt SM, Green DR, Li X, Muoio DM. Birsoy K, et al. Among authors: muoio dm. Cell Chem Biol. 2023 Sep 21;30(9):999-1001. doi: 10.1016/j.chembiol.2023.08.016. Cell Chem Biol. 2023. PMID: 37738954 Free article.
Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program.
Guilherme A, Rowland LA, Wetoska N, Tsagkaraki E, Santos KB, Bedard AH, Henriques F, Kelly M, Munroe S, Pedersen DJ, Ilkayeva OR, Koves TR, Tauer L, Pan M, Han X, Kim JK, Newgard CB, Muoio DM, Czech MP. Guilherme A, et al. Among authors: muoio dm. Cell Rep. 2023 May 30;42(5):112488. doi: 10.1016/j.celrep.2023.112488. Epub 2023 May 8. Cell Rep. 2023. PMID: 37163372 Free PMC article.
145 results