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NXP800 activates the unfolded protein response, altering AR and E2F function to impact castration-resistant prostate cancer growth.
Welti J, Bogdan D, Figueiredo I, Coleman I, Jiménez Vacas J, Liodaki K, Weigl F, Buroni L, Zeng W, Bernett I, Bertan C, Roumeliotis TI, Bhamra A, Rekowski J, Gurel B, Neeb AJ, Ning J, Li D, Gil VS, Riisnaes R, Miranda S, Crespo M, Ferreira A, Tunariu N, Pasqua E, Chessum N, Cheeseman M, Te Poele R, Powers M, Carreira S, Choudhary J, Clarke P, Banerji U, Swain A, Jones K, Yuan W, Workman P, Nelson PS, de Bono JS, Sharp A. Welti J, et al. Among authors: sharp a. Clin Cancer Res. 2025 Jan 9. doi: 10.1158/1078-0432.CCR-24-2386. Online ahead of print. Clin Cancer Res. 2025. PMID: 39787247
Changes in blood pressure after crossover to ultrasound renal denervation.
Bloch MJ, Azizi M, Kirtane AJ, Mahfoud F, Sharp ASP, McGuire M, McClure CK, Weber M, Of The Radiance Investigators OB. Bloch MJ, et al. Among authors: sharp asp. EuroIntervention. 2025 Jan 6;21(1):93-95. doi: 10.4244/EIJ-D-24-00321. EuroIntervention. 2025. PMID: 39773825 Free article. No abstract available.
MTCH2 controls energy demand and expenditure to fuel anabolism during adipogenesis.
Chourasia S, Petucci C, Shoffler C, Abbasian D, Wang H, Han X, Sivan E, Brandis A, Mehlman T, Malitsky S, Itkin M, Sharp A, Rotkopf R, Dassa B, Regev L, Zaltsman Y, Gross A. Chourasia S, et al. Among authors: sharp a. EMBO J. 2025 Jan 3. doi: 10.1038/s44318-024-00335-7. Online ahead of print. EMBO J. 2025. PMID: 39753955 Free article.
Elucidating acquired PARP inhibitor resistance in advanced prostate cancer.
Seed G, Beije N, Yuan W, Bertan C, Goodall J, Lundberg A, Tyler M, Figueiredo I, Pereira R, Baker C, Bogdan D, Gallagher L, Cieslik JP, Greening S, Lambros M, Neves R, Magraner-Pardo L, Fowler G, Ebbs B, Miranda S, Flohr P, Bianchini D, Rescigno P, Porta N, Hall E, Gurel B, Tunariu N, Sharp A, Pettit S, Stoecklein NH, Sandhu S, Quigley D, Lord CJ, Mateo J, Carreira S, de Bono J. Seed G, et al. Among authors: sharp a. Cancer Cell. 2024 Dec 9;42(12):2113-2123.e4. doi: 10.1016/j.ccell.2024.10.015. Epub 2024 Nov 21. Cancer Cell. 2024. PMID: 39577422 Free article.
1,119 results