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Utility of Candidate Genes From an Algorithm Designed to Predict Genetic Risk for Opioid Use Disorder.
Davis CN, Jinwala Z, Hatoum AS, Toikumo S, Agrawal A, Rentsch CT, Edenberg HJ, Baurley JW, Hartwell EE, Crist RC, Gray JC, Justice AC, Gelernter J, Kember RL, Kranzler HR; VA Million Veteran Program. Davis CN, et al. Among authors: kranzler hr. JAMA Netw Open. 2025 Jan 2;8(1):e2453913. doi: 10.1001/jamanetworkopen.2024.53913. JAMA Netw Open. 2025. PMID: 39786773 Free PMC article.
Association of OPRM1 Functional Coding Variant With Opioid Use Disorder: A Genome-Wide Association Study.
Zhou H, Rentsch CT, Cheng Z, Kember RL, Nunez YZ, Sherva RM, Tate JP, Dao C, Xu K, Polimanti R, Farrer LA, Justice AC, Kranzler HR, Gelernter J; Veterans Affairs Million Veteran Program. Zhou H, et al. Among authors: kranzler hr. JAMA Psychiatry. 2020 Oct 1;77(10):1072-1080. doi: 10.1001/jamapsychiatry.2020.1206. JAMA Psychiatry. 2020. PMID: 32492095 Free PMC article.
Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans.
Davis CN, Jinwala Z, Hatoum AS, Toikumo S, Agrawal A, Rentsch CT, Edenberg HJ, Baurley JW, Hartwell EE, Crist RC, Gray JC, Justice AC, Gelernter J, Kember RL, Kranzler HR. Davis CN, et al. Among authors: kranzler hr. medRxiv [Preprint]. 2024 May 16:2024.05.16.24307486. doi: 10.1101/2024.05.16.24307486. medRxiv. 2024. PMID: 38798430 Free PMC article. Preprint.
Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects in brain regions associated with addiction.
Kember RL, Vickers-Smith R, Xu H, Toikumo S, Niarchou M, Zhou H, Hartwell EE, Crist RC, Rentsch CT; Million Veteran Program; Davis LK, Justice AC, Sanchez-Roige S, Kampman KM, Gelernter J, Kranzler HR. Kember RL, et al. Among authors: kranzler hr. Nat Neurosci. 2022 Oct;25(10):1279-1287. doi: 10.1038/s41593-022-01160-z. Epub 2022 Sep 28. Nat Neurosci. 2022. PMID: 36171425 Free PMC article.
Genetics of drug dependence.
Gelernter J, Kranzler HR. Gelernter J, et al. Among authors: kranzler hr. Dialogues Clin Neurosci. 2010;12(1):77-84. doi: 10.31887/DCNS.2010.12.1/jgelernter. Dialogues Clin Neurosci. 2010. PMID: 20373669 Free PMC article. Review.
642 results