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Page 1
Single-cell RNA sequencing highlights the role of distinct natural killer subsets in sporadic amyotrophic lateral sclerosis.
Álvarez-Sánchez E, Carbayo Á, Valle-Tamayo N, Muñoz L, Aumatell J, Torres S, Rubio-Guerra S, García-Castro J, Selma-González J, Alcolea D, Turon-Sans J, Lleó A, Illán-Gala I, Fortea J, Rojas-García R, Dols-Icardo O. Álvarez-Sánchez E, et al. Among authors: alcolea d. J Neuroinflammation. 2025 Jan 23;22(1):15. doi: 10.1186/s12974-025-03347-0. J Neuroinflammation. 2025. PMID: 39849490
Cerebral Microbleeds and Amyloid Pathology Estimates From the Amyloid Biomarker Study.
Oomens JE, van Gils V, Vos SJB, Freeze WM, Maserejian NN, Curiale G, Gillis C, Boada M, van der Flier WM, Hort J, Johnson SC, Lleó A, Ramakers IH, Rodrigue KM, Sánchez-Juan P, Sarazin M, Scarmeas N, Zetterberg H, Alcolea D, Barkhof F, Blennow K, Bottlaender M, den Braber A, Cerman J, Drake-Perez M, Fortea J, Handels R, Ingala S, Jiménez-Bonilla JF, Karavasilis S, Lagarde J, Legdeur N, Lorenzini L, Marquié M, Moonen JEF, Olivieri P, Orellana A, Ossenkoppele R, Rivera-Rivera LA, Rodríguez-Rodriguez E, Ruiz Laza A, Teunissen CE, Tijms BM, Velonakis G, Verhey FRJ, Visser PJ, Jansen WJ; European Prevention of Alzheimer’s Dementia (EPAD) Consortium; Fundació ACE Healthy Brain Initiative (FACEHBI) Study Group; BIOFACE Study Group. Oomens JE, et al. Among authors: alcolea d. JAMA Netw Open. 2025 Jan 2;8(1):e2455571. doi: 10.1001/jamanetworkopen.2024.55571. JAMA Netw Open. 2025. PMID: 39841474 Free PMC article.
Depressive Symptoms and Amyloid Pathology.
Wiels WA, Oomens JE, Engelborghs S, Baeken C, von Arnim CAF, Boada M, Didic M, Dubois B, Fladby T, van der Flier WM, Frisoni GB, Fröhlich L, Gill KD, Grimmer T, Hildebrandt H, Hort J, Itoh Y, Iwatsubo T, Klimkowicz-Mrowiec A, Lee DY, Lleó A, Martinez-Lage P, de Mendonça A, Meyer PT, Kapaki EN, Parchi P, Pardini M, Parnetti L, Popp J, Rami L, Reiman EM, Rinne JO, Rodrigue KM, Sánchez-Juan P, Santana I, Sarazin M, Scarmeas N, Skoog I, Snyder PJ, Sperling RA, Villeneuve S, Wallin A, Wiltfang J, Zetterberg H, Ossenkoppele R, Verhey FRJ, Vos SJB, Visser PJ, Jansen WJ; Amyloid Biomarker Study group; Alzheimer’s Disease Neuroimaging Initiative (ADNI), the A4 Study group, Dominantly Inherited Alzheimer Network (DIAN), European Prevention of Alzheimer’s Dementia (EPAD) consortium, Fundació ACE Healthy Brain Initiative (FACEHBI), Harvard Aging Brain Stud; Alcolea D, Altomare D, Baiardi S, Baldeiras I, Bateman RJ, Blennow K, Bottlaender M, den Braber A, van Buchem MA, Byun MS, Cerman J, Chen K, Chipi E, Day GS, Drzezga A, Eckerström M, Ekblad LL, Epelbaum S, Förster S, Fortea J, Freund-Levi Y, Frings L, Guedj E, Hausner L, Hellwig S, Huey ED, Jiménez-Bonilla JF, Johnson KA, Juaristi A… See abstract for full author list ➔ Wiels WA, et al. Among authors: alcolea d. JAMA Psychiatry. 2025 Jan 22. doi: 10.1001/jamapsychiatry.2024.4305. Online ahead of print. JAMA Psychiatry. 2025. PMID: 39841452
Impaired Cerebrospinal Fluid Lipoprotein-Mediated Cholesterol Delivery to Neurons in Alzheimer's Disease.
Borràs C, Canyelles M, Santos D, Rotllan N, Núñez E, Vázquez J, Maspoch D, Cano-Sarabia M, Carmona-Iragui M, Sirisi S, Lleó A, Fortea J, Alcolea D, Blanco-Vaca F, Escolà-Gil JC, Tondo M. Borràs C, et al. Among authors: alcolea d. Res Sq [Preprint]. 2024 Dec 23:rs.3.rs-5682870. doi: 10.21203/rs.3.rs-5682870/v1. Res Sq. 2024. PMID: 39764088 Free PMC article. Preprint.
Posterior Cortical Atrophy Due to Alzheimer Disease in a Person With Down Syndrome: A Case Report.
Rodríguez-Baz Í, Benejam B, Morcillo-Nieto AO, Vaqué-Alcázar L, Arriola-Infante JE, Camacho V, Aranha MR, Carmona-Iragui M, Videla L, Barroeta I, Fernández S, Zsadanyi SE, Giménez S, Arranz J, Maure Blesa L, Alcolea D, Lleó A, Bejanin A, Fortea J. Rodríguez-Baz Í, et al. Among authors: alcolea d. Neurology. 2025 Jan 14;104(1):e210179. doi: 10.1212/WNL.0000000000210179. Epub 2024 Dec 17. Neurology. 2025. PMID: 39689339
Plasma p-tau212 as a biomarker of sporadic and Down Syndrome Alzheimer's disease.
Kac PR, Alcolea D, Montoliu-Gaya L, Fernández S, Rodriguez JL, Maure L, González-Ortiz F, Benejam B, Turton M, Barroeta I, Harrison P, Videla L, Ashton NJ, Lleó A, Zetterberg H, Carmona-Iragui M, Karikari TK, Fortea J, Blennow K. Kac PR, et al. Among authors: alcolea d. medRxiv [Preprint]. 2024 Nov 2:2024.10.31.24316469. doi: 10.1101/2024.10.31.24316469. medRxiv. 2024. PMID: 39574868 Free PMC article. Preprint.
Diagnosis of Alzheimer's disease using plasma biomarkers adjusted to clinical probability.
Therriault J, Janelidze S, Benedet AL, Ashton NJ, Arranz Martínez J, Gonzalez-Escalante A, Bellaver B, Alcolea D, Vrillon A, Karim H, Mielke MM, Hyung Hong C, Roh HW, Contador J, Puig Pijoan A, Algeciras-Schimnich A, Vemuri P, Graff-Radford J, Lowe VJ, Karikari TK, Jonaitis E, Brum W, Tissot C, Servaes S, Rahmouni N, Macedo AC, Stevenson J, Fernandez-Arias J, Wang YT, Woo MS, Friese MA, Jia WL, Dumurgier J, Hourregue C, Cognat E, Ferreira PL, Vitali P, Johnson S, Pascoal TA, Gauthier S, Lleó A, Paquet C, Petersen RC, Salmon D, Mattsson-Carlgren N, Palmqvist S, Stomrud E, Galasko D, Son SJ, Zetterberg H, Fortea J, Suárez-Calvet M, Jack CR Jr, Blennow K, Hansson O, Rosa-Neto P. Therriault J, et al. Among authors: alcolea d. Nat Aging. 2024 Nov;4(11):1529-1537. doi: 10.1038/s43587-024-00731-y. Epub 2024 Nov 12. Nat Aging. 2024. PMID: 39533113 Free PMC article.
Clinical value of plasma pTau181 to predict Alzheimer's disease pathology in a large real-world cohort of a memory clinic.
Cano A, Capdevila M, Puerta R, Arranz J, Montrreal L, de Rojas I, García-González P, Olivé C, García-Gutiérrez F, Sotolongo-Grau O, Orellana A, Aguilera N, Ramis M, Rosende-Roca M, Lleó A, Fortea J, Tartari JP, Lafuente A, Vargas L, Pérez-Cordón A, Muñoz N, Sanabria Á, Alegret M, Morató X, Tárraga L, Fernández V, Marquié M, Valero S, Alcolea D, Boada M, Ruiz A. Cano A, et al. Among authors: alcolea d. EBioMedicine. 2024 Oct;108:105345. doi: 10.1016/j.ebiom.2024.105345. Epub 2024 Sep 18. EBioMedicine. 2024. PMID: 39299003 Free PMC article.
Large-scale CSF proteome profiling identifies biomarkers for accurate diagnosis of Frontotemporal Dementia.
Hok-A-Hin YS, Vermunt L, Peeters CFW, van der Ende EL, de Boer SCM, Meeter LH, van Swieten JC, Hu WT, Lleó A, Alcolea D, Engelborghs S, Sieben A, Chen-Plotkin A, Irwin DJ, van der Flier WM, Pijnenburg YAL, Teunissen CE, Del Campo M. Hok-A-Hin YS, et al. Among authors: alcolea d. medRxiv [Preprint]. 2024 Aug 20:2024.08.19.24312100. doi: 10.1101/2024.08.19.24312100. medRxiv. 2024. PMID: 39228745 Free PMC article. Preprint.
185 results