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Biomarkers.
Joseph-Mathurin N, Shen Y, Friedrichsen KA, Chen CD, McCullough AA, Strain JF, Shirzadi Z, Chen G, Massoumzadeh P, Gordon BA, Llibre-Guerra JJ, Hassenstab JJ, Ibanez L, Lu R, Schultz SA, Chhatwal JP, Morris JC, Perrin RJ, An H, Xiong C, Klein RS, Jack CR Jr, Bateman RJ, McDade E, Benzinger TLS, Cruchaga C, Network DIA. Joseph-Mathurin N, et al. Among authors: chen cd. Alzheimers Dement. 2024 Dec;20 Suppl 2(Suppl 2):e084578. doi: 10.1002/alz.084578. Alzheimers Dement. 2024. PMID: 39786219 Free PMC article.
Biomarkers.
Salvadó G, Barthélemy NR, Schindler SE, He Y, Janelidze S, Collij LE, Saef BA, Henson RL, Chen CD, Gordon BA, Li Y, Joie R, Benzinger TLS, Morris JC, Mattsson-Carlgren N, Palmqvist S, Ossenkoppele R, Rabinovici GD, Stomrud E, Bateman RJ, Hansson O. Salvadó G, et al. Among authors: chen cd. Alzheimers Dement. 2024 Dec;20 Suppl 2(Suppl 2):e089139. doi: 10.1002/alz.089139. Alzheimers Dement. 2024. PMID: 39785577 Free PMC article.
Developing Topics.
McCullough AA, Cao Y, Chen CD, Gordon BA, Cruchaga C, Goate AM, Hassenstab JJ, Ibanez L, Li Y, Perrin RJ, Renton AE, Xiong C, Salloway S, Llibre-Guerra JJ, Clifford DB, McDade E, Bateman RJ, Benzinger TLS, Wang G, Joseph-Mathurin N; DIAN study team. McCullough AA, et al. Among authors: chen cd. Alzheimers Dement. 2024 Dec;20 Suppl 8(Suppl 8):e095570. doi: 10.1002/alz.095570. Alzheimers Dement. 2024. PMID: 39783393 Free PMC article. Clinical Trial.
Developing Topics.
Chen CD, Franklin EE, Li Y, Joseph-Mathurin N, Burns A, Hobbs DA, McCullough AA, Schultz SA, Wang G, Benzinger TLS, Bateman RJ, Perrin RJ. Chen CD, et al. Alzheimers Dement. 2024 Dec;20 Suppl 8(Suppl 8):e095436. doi: 10.1002/alz.095436. Alzheimers Dement. 2024. PMID: 39783368 Free PMC article.
Alzheimer's Imaging Consortium.
Joseph-Mathurin N, Shen Y, Friedrichsen KA, Chen CD, McCullough AA, Strain JF, Shirzadi Z, Chen G, Massoumzadeh P, Gordon BA, Llibre-Guerra JJ, Hassenstab JJ, Ibanez L, Lu R, Schultz SA, Chhatwal JP, Morris JC, Perrin RJ, An H, Xiong C, Klein RS, Jack CR Jr, Bateman RJ, McDade E, Benzinger TLS, Cruchaga C. Joseph-Mathurin N, et al. Among authors: chen cd. Alzheimers Dement. 2024 Dec;20 Suppl 9(Suppl 9):e093619. doi: 10.1002/alz.093619. Alzheimers Dement. 2024. PMID: 39783248 Free PMC article.
Nuclear Control of Mitochondrial Homeostasis and Venetoclax Efficacy in AML via COX4I1.
Zhang L, Zhang H, Wang TY, Li M, Chan AKN, Kang H, Foong LC, Liu Q, Pokharel SP, Mattson NM, Singh P, Elsayed Z, Kuang B, Wang X, Rosen ST, Chen J, Yang L, Chou TF, Su R, Chen CD. Zhang L, et al. Among authors: chen cd. Adv Sci (Weinh). 2024 Dec 23:e2404620. doi: 10.1002/advs.202404620. Online ahead of print. Adv Sci (Weinh). 2024. PMID: 39716856
Desipramine reverses remote memory deficits by activating calmodulin-CaMKII pathway in a UTX knockout mouse model of Kabuki syndrome.
Chen L, Li Y, Liu M, Lan Z, Zhang X, Yang X, Zhao Q, Wang S, Xu L, Zhou Y, Kuang Y, Suzuki T, Tabuchi K, Takahashi E, Zhou M, Chen CD, Xu T, Li W. Chen L, et al. Among authors: chen cd. Gen Psychiatr. 2024 Oct 29;37(5):e101430. doi: 10.1136/gpsych-2023-101430. eCollection 2024. Gen Psychiatr. 2024. PMID: 39493372 Free PMC article.
γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS).
Schultz SA, Liu L, Schultz AP, Fitzpatrick CD, Levin R, Bellier JP, Shirzadi Z, Joseph-Mathurin N, Chen CD, Benzinger TLS, Day GS, Farlow MR, Gordon BA, Hassenstab JJ, Jack CR Jr, Jucker M, Karch CM, Lee JH, Levin J, Perrin RJ, Schofield PR, Xiong C, Johnson KA, McDade E, Bateman RJ, Sperling RA, Selkoe DJ, Chhatwal JP; Dominantly Inherited Alzheimer Network. Schultz SA, et al. Among authors: chen cd. Lancet Neurol. 2024 Sep;23(9):913-924. doi: 10.1016/S1474-4422(24)00236-9. Epub 2024 Jul 26. Lancet Neurol. 2024. PMID: 39074479
Spatial extent as a sensitive amyloid-PET metric in preclinical Alzheimer's disease.
Farrell ME, Thibault EG, Becker JA, Price JC, Healy BC, Hanseeuw BJ, Buckley RF, Jacobs HIL, Schultz AP, Chen CD, Sperling RA, Johnson KA. Farrell ME, et al. Among authors: chen cd. Alzheimers Dement. 2024 Aug;20(8):5434-5449. doi: 10.1002/alz.14036. Epub 2024 Jul 10. Alzheimers Dement. 2024. PMID: 38988055 Free PMC article.
Deconstructing pathological tau by biological process in early stages of Alzheimer disease: a method for quantifying tau spatial spread in neuroimaging.
Doering S, McCullough A, Gordon BA, Chen CD, McKay N, Hobbs D, Keefe S, Flores S, Scott J, Smith H, Jarman S, Jackson K, Hornbeck RC, Ances BM, Xiong C, Aschenbrenner AJ, Hassenstab J, Cruchaga C, Daniels A, Bateman RJ; Dominantly Inherited Alzheimer Network (DIAN) Investigators; Morris JC, Benzinger TLS. Doering S, et al. Among authors: chen cd. EBioMedicine. 2024 May;103:105080. doi: 10.1016/j.ebiom.2024.105080. Epub 2024 Mar 28. EBioMedicine. 2024. PMID: 38552342 Free PMC article.
425 results