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19 results

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Activation of SIRT1 by SRT1720 alleviates dyslipidemia, improves insulin sensitivity and exhibits liver-protective effects in diabetic rats on a high-fat diet: New insights into the SIRT1/Nrf2/NFκB signaling pathway.
Elmorsy EA, Elsisi HA, Alkhamiss AS, Alsoqih NS, Khodeir MM, Alsalloom AA, Almeman AA, Elghandour SR, Nadwa EH, Khalifa AK, Khaled BEA, Ramadan A, Kamal MM, Alsaeed TS, Alharbi MS, Abdel-Moneim AH, Ellethy AT, Saber S. Elmorsy EA, et al. Among authors: alkhamiss as. Eur J Pharm Sci. 2025 Jan 6;206:107002. doi: 10.1016/j.ejps.2025.107002. Online ahead of print. Eur J Pharm Sci. 2025. PMID: 39778687 Free article.
Activation of AMPK/SIRT1/FOXO3a signaling by BMS-477118 (saxagliptin) mitigates chronic colitis in rats: uncovering new anti-inflammatory and antifibrotic roles.
Elmorsy EA, Youssef ME, Abdel-Hamed MR, Amer MM, Elghandour SR, Alkhamiss AS, Mohamed NB, Khodeir MM, Elsisi HA, Alsaeed TS, Kamal MM, Ellethy AT, Elesawy BH, Saber S. Elmorsy EA, et al. Among authors: alkhamiss as. Front Pharmacol. 2024 Sep 18;15:1456058. doi: 10.3389/fphar.2024.1456058. eCollection 2024. Front Pharmacol. 2024. PMID: 39359253 Free PMC article.
STA-9090 in combination with a statin exerts enhanced protective effects in rats fed a high-fat diet and exposed to diethylnitrosamine and thioacetamide.
Abdelhamid AM, Saber S, Hamad RS, Abdel-Reheim MA, Ellethy AT, Amer MM, Abdel-Hamed MR, Mohamed EA, Ahmed SS, Elsisi HA, Khodeir MM, Alkhamiss AS, A AA, Abu Elgasim MAE, Almansour ZH, Elesawy BH, Elmorsy EA. Abdelhamid AM, et al. Among authors: alkhamiss as. Front Pharmacol. 2024 Sep 4;15:1454829. doi: 10.3389/fphar.2024.1454829. eCollection 2024. Front Pharmacol. 2024. PMID: 39309001 Free PMC article.
Prediction of promiscuous multiepitope-based peptide vaccine against RdRp of rotavirus using immunoinformatics studies.
Almohaimeed HM, Abdulfattah AM, Alsulaimani F, Alshammary A, Almohaini MO, Almehiny KA, Hershan AA, Alkhamiss AS, Alghsham RS, Ghabban H, Soliman MH, Alorabi JA, Abdulmonem WA. Almohaimeed HM, et al. Among authors: alkhamiss as. Rev Inst Med Trop Sao Paulo. 2024 Sep 6;66:e55. doi: 10.1590/S1678-9946202466055. eCollection 2024. Rev Inst Med Trop Sao Paulo. 2024. PMID: 39258658 Free PMC article.
Modulating the HSP90 control over NFκB/NLRP3/Caspase-1 axis is a new therapeutic target in the management of liver fibrosis: Insights into the role of TAS-116 (Pimitespib).
Elmorsy EA, Saber S, Hamad RS, Abdel-Reheim MA, Nadwa EH, Alibrahim AOE, Alkhamiss AS, AlSalloom AA, Mohamed EA, Nour-El-Din M, Amer MM, Abdel-Hamed MR, Mohamed NB, Abozaid L, Mostafa-Hedeab G, Ahmed SS, Taha HH, Khalifa AK. Elmorsy EA, et al. Among authors: alkhamiss as. Life Sci. 2024 Oct 1;354:122966. doi: 10.1016/j.lfs.2024.122966. Epub 2024 Aug 13. Life Sci. 2024. PMID: 39147320 Free article.
Hedgehog signaling is a promising target for the treatment of hepatic fibrogenesis: a new management strategy using itraconazole-loaded nanoparticles.
Elmorsy EA, Saber S, Kira AY, Alghasham A, Abdel-Hamed MR, Amer MM, Mohamed EA, AlSalloom A A, Alkhamiss AS, Hamad RS, Abdel-Reheim MA, Ellethy AT, Elsisi HA, Alsharidah M, Elghandour SR, Elnawawy T, Abdelhady R. Elmorsy EA, et al. Among authors: alkhamiss as. Front Pharmacol. 2024 May 14;15:1377980. doi: 10.3389/fphar.2024.1377980. eCollection 2024. Front Pharmacol. 2024. PMID: 38808257 Free PMC article.
Novel mutation in alpha-spectrin gene in Saudi patients with hereditary spherocytosis.
Alshomar A, Ahmed AA, Rasheed Z, Alhumaydhi FA, Alsagaby S, Aljohani ASM, Alkhamiss AS, Alghsham R, Althwab SA, Khan MI, Fernández N, Al Abdulmonem W. Alshomar A, et al. Among authors: alkhamiss as. Nucleosides Nucleotides Nucleic Acids. 2024;43(11):1282-1301. doi: 10.1080/15257770.2024.2310703. Epub 2024 Feb 6. Nucleosides Nucleotides Nucleic Acids. 2024. PMID: 38319988
19 results