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Withaferin A inhibits Chikungunya virus nsP2 protease and shows antiviral activity in the cell culture and mouse model of virus infection.
Sharma KB, Subramani C, Ganesh K, Sharma A, Basu B, Balyan S, Sharma G, Ka S, Deb A, Srivastava M, Chugh S, Sehrawat S, Bharadwaj K, Rout A, Sahoo PK, Saurav S, Motiani RK, Singh R, Jain D, Asthana S, Wadhwa R, Vrati S. Sharma KB, et al. Among authors: singh r. PLoS Pathog. 2024 Dec 30;20(12):e1012816. doi: 10.1371/journal.ppat.1012816. eCollection 2024 Dec. PLoS Pathog. 2024. PMID: 39775571 Free PMC article.
Polyphosphate kinase-1 regulates bacterial and host metabolic pathways involved in pathogenesis of Mycobacterium tuberculosis.
Chugh S, Tiwari P, Suri C, Gupta SK, Singh P, Bouzeyen R, Kidwai S, Srivastava M, Rameshwaram NR, Kumar Y, Asthana S, Singh R. Chugh S, et al. Among authors: singh r, singh p. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2309664121. doi: 10.1073/pnas.2309664121. Epub 2024 Jan 3. Proc Natl Acad Sci U S A. 2024. PMID: 38170746 Free PMC article.
Identification and optimization of pyridine carboxamide-based scaffold as a drug lead for Mycobacterium tuberculosis.
Singh P, Kumar A, Sharma P, Chugh S, Kumar A, Sharma N, Gupta S, Singh M, Kidwai S, Sankar J, Taneja N, Kumar Y, Dhiman R, Mahajan D, Singh R. Singh P, et al. Among authors: singh m, singh r. Antimicrob Agents Chemother. 2024 Feb 7;68(2):e0076623. doi: 10.1128/aac.00766-23. Epub 2024 Jan 9. Antimicrob Agents Chemother. 2024. PMID: 38193667 Free PMC article.
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