Puchkov M - Search Results

1

Pharmacokinetics and Pharmacodynamics of an Innovative Psychedelic N,N-Dimethyltryptamine/Harmine Formulation in Healthy Participants: A Randomized Controlled Trial.

Mueller MJ, Aicher HD, Dornbierer DA, Marten L, Suay D, Meling D, Elsner C, Wicki IA, Müller J, Poetzsch SN, Caflisch L, Hempe A, Steinhart CP, Puchkov M, Kost J, Landolt HP, Seifritz E, Quednow BB, Scheidegger M. Mueller MJ, et al. Among authors: puchkov m. Int J Neuropsychopharmacol. 2025 Jan 8:pyaf001. doi: 10.1093/ijnp/pyaf001. Online ahead of print. Int J Neuropsychopharmacol. 2025. PMID: 39774840 Free article.

2

Overcoming the clinical challenges of traditional ayahuasca: a first-in-human trial exploring novel routes of administration of N,N-Dimethyltryptamine and harmine.

Dornbierer DA, Marten L, Mueller J, Aicher HD, Mueller MJ, Boxler M, Kometer M, Kosanic D, von Rotz R, Puchkov M, Kraemer T, Landolt HP, Seifritz E, Scheidegger M. Dornbierer DA, et al. Among authors: puchkov m. Front Pharmacol. 2023 Nov 27;14:1246892. doi: 10.3389/fphar.2023.1246892. eCollection 2023. Front Pharmacol. 2023. PMID: 38089057 Free PMC article.

3

Effects of Sub-Anesthetic Oro-Mucosal Dexmedetomidine on Sleep in Humans: A Randomized, Controlled Pharmacokinetics-Pharmacodynamics Study.

Schnider LK, Ratajczak M, Wespi R, Kientsch JG, Bavato F, Marten L, Kost J, Puchkov M, Eicher C, Boxler M, Voegel CD, Bosch OG, van Someren E, Dornbierer DA, Landolt HP. Schnider LK, et al. Among authors: puchkov m. Anesthesiology. 2024 Nov 27. doi: 10.1097/ALN.0000000000005314. Online ahead of print. Anesthesiology. 2024. PMID: 39601561

4

Advanced analysis of disintegrating pharmaceutical compacts using deep learning-based segmentation of time-resolved micro-tomography images.

Waldner S, Wendelspiess E, Detampel P, Schlepütz CM, Huwyler J, Puchkov M. Waldner S, et al. Among authors: puchkov m. Heliyon. 2024 Feb 12;10(4):e26025. doi: 10.1016/j.heliyon.2024.e26025. eCollection 2024 Feb 29. Heliyon. 2024. PMID: 38384517 Free PMC article.

5

The processes behind drug loading and release in porous drug delivery systems.

Farzan M, Roth R, Schoelkopf J, Huwyler J, Puchkov M. Farzan M, et al. Among authors: puchkov m. Eur J Pharm Biopharm. 2023 Aug;189:133-151. doi: 10.1016/j.ejpb.2023.05.019. Epub 2023 May 23. Eur J Pharm Biopharm. 2023. PMID: 37230292 Review.

6

Colonic delivery of metronidazole-loaded capsules for local treatment of bacterial infections: A clinical pharmacoscintigraphy study.

Preisig D, Varum F, Bravo R, Hartig C, Spleiss J, Abbes S, Caobelli F, Wild D, Puchkov M, Huwyler J, Haschke M. Preisig D, et al. Among authors: puchkov m. Eur J Pharm Biopharm. 2021 Aug;165:22-30. doi: 10.1016/j.ejpb.2021.05.002. Epub 2021 May 7. Eur J Pharm Biopharm. 2021. PMID: 33971274 Free article. Clinical Trial.

7

High Acceptability of an Orally Dispersible Tablet Formulation by Children.

Wagner-Hattler L, Kiene K, Bielicki J, Pfister M, Puchkov M, Huwyler J. Wagner-Hattler L, et al. Among authors: puchkov m. Children (Basel). 2021 Mar 5;8(3):194. doi: 10.3390/children8030194. Children (Basel). 2021. PMID: 33807822 Free PMC article.

8

Particle Forming Amorphous Solid Dispersions: A Mechanistic Randomized Pharmacokinetic Study in Humans.

Schittny A, Waldner S, Duthaler U, Vorobyev A, Abramovich R, Krähenbühl S, Puchkov M, Huwyler J. Schittny A, et al. Among authors: puchkov m. Pharmaceutics. 2021 Mar 17;13(3):401. doi: 10.3390/pharmaceutics13030401. Pharmaceutics. 2021. PMID: 33803049 Free PMC article.

9

Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2.

Bachmann F, Duthaler U, Meyer Zu Schwabedissen HE, Puchkov M, Huwyler J, Haschke M, Krähenbühl S. Bachmann F, et al. Among authors: puchkov m. Clin Pharmacol Ther. 2021 Jun;109(6):1505-1516. doi: 10.1002/cpt.2141. Epub 2021 Jan 19. Clin Pharmacol Ther. 2021. PMID: 33336382 Free PMC article.

10

Spontaneous In Situ Formation of Liposomes from Inert Porous Microparticles for Oral Drug Delivery.

Farzan M, Québatte G, Strittmatter K, Hilty FM, Schoelkopf J, Huwyler J, Puchkov M. Farzan M, et al. Among authors: puchkov m. Pharmaceutics. 2020 Aug 15;12(8):777. doi: 10.3390/pharmaceutics12080777. Pharmaceutics. 2020. PMID: 32824155 Free PMC article.

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