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Page 1
An engineered immunogen activates diverse HIV broadly neutralizing antibody precursors and promotes acquisition of improbable mutations.
Swanson OM, Zhang QE, Van Itallie E, Tian M, Brown AR, Harris C, Kapingidza AB, Rhodes B, Smith LM, Venkatayogi S, Cronin K, Frazier M, Parks R, Bar M, Jiang C, Martin Beem JS, Cheng HL, Davis J, McGovern K, Newman A, Edwards RJ, Cain D, Alam SM, Wiehe K, Saunders KO, Acharya P, Alt F, Haynes BF, Azoitei ML. Swanson OM, et al. Among authors: azoitei ml. Sci Transl Med. 2025 Jan 8;17(780):eadr2218. doi: 10.1126/scitranslmed.adr2218. Epub 2025 Jan 8. Sci Transl Med. 2025. PMID: 39772772
A high affinity monoclonal antibody against HLA-E-VL9 enhances natural killer cell anti-tumor killing.
Hwang JK, Marston DJ, Wrapp D, Li D, Tuyishime M, Brackenridge S, Rhodes B, Quastel M, Kapingidza AB, Gater J, Harner A, Wang Y, Rountree W, Ferrari G, Borrow P, McMichael AJ, Gillespie GM, Haynes BF, Azoitei ML. Hwang JK, et al. Among authors: azoitei ml. bioRxiv [Preprint]. 2024 Jul 11:2024.07.08.602401. doi: 10.1101/2024.07.08.602401. bioRxiv. 2024. PMID: 39026709 Free PMC article. Preprint.
Engineered immunogens to elicit antibodies against conserved coronavirus epitopes.
Kapingidza AB, Marston DJ, Harris C, Wrapp D, Winters K, Mielke D, Xiaozhi L, Yin Q, Foulger A, Parks R, Barr M, Newman A, Schäfer A, Eaton A, Flores JM, Harner A, Catanzaro NJ Jr, Mallory ML, Mattocks MD, Beverly C, Rhodes B, Mansouri K, Van Itallie E, Vure P, Dunn B, Keyes T, Stanfield-Oakley S, Woods CW, Petzold EA, Walter EB, Wiehe K, Edwards RJ, Montefiori DC, Ferrari G, Baric R, Cain DW, Saunders KO, Haynes BF, Azoitei ML. Kapingidza AB, et al. Among authors: azoitei ml. Nat Commun. 2023 Nov 30;14(1):7897. doi: 10.1038/s41467-023-43638-9. Nat Commun. 2023. PMID: 38036525 Free PMC article.
Engineered Immunogens to Elicit Antibodies Against Conserved Coronavirus Epitopes.
Kapingidza B, Marston DJ, Harris C, Wrapp D, Winters K, Mielke D, Xiaozhi L, Yin Q, Foulger A, Parks R, Barr M, Newman A, Schäfer A, Eaton A, Flores JM, Harner A, Cantazaro NJ, Mallory ML, Mattocks MD, Beverly C, Rhodes B, Mansouri K, Itallie EV, Vure P, Manness B, Keyes T, Stanfield-Oakley S, Woods CW, Petzold EA, Walter EB, Wiehe K, Edwards RJ, Montefiori D, Ferrari G, Baric R, Cain DW, Saunders KO, Haynes BF, Azoitei ML. Kapingidza B, et al. Among authors: azoitei ml. bioRxiv [Preprint]. 2023 Sep 17:2023.02.27.530277. doi: 10.1101/2023.02.27.530277. bioRxiv. 2023. Update in: Nat Commun. 2023 Nov 30;14(1):7897. doi: 10.1038/s41467-023-43638-9 PMID: 36909627 Free PMC article. Updated. Preprint.
Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.
Li D, Brackenridge S, Walters LC, Swanson O, Harlos K, Rozbesky D, Cain DW, Wiehe K, Scearce RM, Barr M, Mu Z, Parks R, Quastel M, Edwards RJ, Wang Y, Rountree W, Saunders KO, Ferrari G, Borrow P, Jones EY, Alam SM, Azoitei ML, Gillespie GM, McMichael AJ, Haynes BF. Li D, et al. Among authors: azoitei ml. Commun Biol. 2022 Mar 28;5(1):271. doi: 10.1038/s42003-022-03183-5. Commun Biol. 2022. PMID: 35347236 Free PMC article.
Rapid selection of HIV envelopes that bind to neutralizing antibody B cell lineage members with functional improbable mutations.
Swanson O, Rhodes B, Wang A, Xia SM, Parks R, Chen H, Sanzone A, Cooper M, Louder MK, Lin BC, Doria-Rose NA, Bonsignori M, Saunders KO, Wiehe K, Haynes BF, Azoitei ML. Swanson O, et al. Among authors: azoitei ml. Cell Rep. 2021 Aug 17;36(7):109561. doi: 10.1016/j.celrep.2021.109561. Cell Rep. 2021. PMID: 34407396 Free PMC article.
Software for lattice light-sheet imaging of FRET biosensors, illustrated with a new Rap1 biosensor.
O'Shaughnessy EC, Stone OJ, LaFosse PK, Azoitei ML, Tsygankov D, Heddleston JM, Legant WR, Wittchen ES, Burridge K, Elston TC, Betzig E, Chew TL, Adalsteinsson D, Hahn KM. O'Shaughnessy EC, et al. Among authors: azoitei ml. J Cell Biol. 2019 Sep 2;218(9):3153-3160. doi: 10.1083/jcb.201903019. Epub 2019 Aug 23. J Cell Biol. 2019. PMID: 31444239 Free PMC article.
15 results