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PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I IFN pathway.
Hodgins JJ, Abou-Hamad J, O'Dwyer CE, Hagerman A, Yakubovich E, Tanese de Souza C, Marotel M, Buchler A, Fadel S, Park MM, Fong-McMaster C, Crupi MF, Makinson OJ, Kurdieh R, Rezaei R, Dhillon HS, Ilkow CS, Bell JC, Harper ME, Rotstein BH, Auer RC, Vanderhyden BC, Sabourin LA, Bourgeois-Daigneault MC, Cook DP, Ardolino M. Hodgins JJ, et al. Among authors: bourgeois daigneault mc. J Exp Med. 2024 Jul 1;221(7):e20221721. doi: 10.1084/jem.20221721. Epub 2024 Jun 13. J Exp Med. 2024. PMID: 38869480 Free PMC article.
High Levels of MFG-E8 Confer a Good Prognosis in Prostate and Renal Cancer Patients.
Geoffroy K, Laplante P, Clairefond S, Azzi F, Trudel D, Lattouf JB, Stagg J, Saad F, Mes-Masson AM, Bourgeois-Daigneault MC, Cailhier JF. Geoffroy K, et al. Among authors: bourgeois daigneault mc. Cancers (Basel). 2022 Jun 4;14(11):2790. doi: 10.3390/cancers14112790. Cancers (Basel). 2022. PMID: 35681775 Free PMC article.
Adjuvant oncolytic virotherapy for personalized anti-cancer vaccination.
Roy DG, Geoffroy K, Marguerie M, Khan ST, Martin NT, Kmiecik J, Bobbala D, Aitken AS, de Souza CT, Stephenson KB, Lichty BD, Auer RC, Stojdl DF, Bell JC, Bourgeois-Daigneault MC. Roy DG, et al. Among authors: bourgeois daigneault mc. Nat Commun. 2021 May 11;12(1):2626. doi: 10.1038/s41467-021-22929-z. Nat Commun. 2021. PMID: 33976179 Free PMC article.
The pros and cons of interferons for oncolytic virotherapy.
Geoffroy K, Bourgeois-Daigneault MC. Geoffroy K, et al. Among authors: bourgeois daigneault mc. Cytokine Growth Factor Rev. 2020 Dec;56:49-58. doi: 10.1016/j.cytogfr.2020.07.002. Epub 2020 Jul 3. Cytokine Growth Factor Rev. 2020. PMID: 32694051 Review.
Methionine Metabolism Shapes T Helper Cell Responses through Regulation of Epigenetic Reprogramming.
Roy DG, Chen J, Mamane V, Ma EH, Muhire BM, Sheldon RD, Shorstova T, Koning R, Johnson RM, Esaulova E, Williams KS, Hayes S, Steadman M, Samborska B, Swain A, Daigneault A, Chubukov V, Roddy TP, Foulkes W, Pospisilik JA, Bourgeois-Daigneault MC, Artyomov MN, Witcher M, Krawczyk CM, Larochelle C, Jones RG. Roy DG, et al. Among authors: bourgeois daigneault mc. Cell Metab. 2020 Feb 4;31(2):250-266.e9. doi: 10.1016/j.cmet.2020.01.006. Cell Metab. 2020. PMID: 32023446 Free article.
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