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Non-ionotropic signaling through the NMDA receptor GluN2B carboxy terminal domain drives morphological plasticity of dendritic spines and reverses fragile X phenotypes in mouse hippocampus.
Barnes SA, Thomazeau A, Finnie PSB, Heinrich MJ, Heynen AJ, Komiyama NH, Grant SGN, Menniti FS, Osterweil EK, Bear MF. Barnes SA, et al. Among authors: heynen aj. bioRxiv [Preprint]. 2024 Dec 23:2024.12.15.628559. doi: 10.1101/2024.12.15.628559. bioRxiv. 2024. PMID: 39764032 Free PMC article. Preprint.
Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome.
McCamphill PK, Stoppel LJ, Senter RK, Lewis MC, Heynen AJ, Stoppel DC, Sridhar V, Collins KA, Shi X, Pan JQ, Madison J, Cottrell JR, Huber KM, Scolnick EM, Holson EB, Wagner FF, Bear MF. McCamphill PK, et al. Among authors: heynen aj. Sci Transl Med. 2020 May 20;12(544):eaam8572. doi: 10.1126/scitranslmed.aam8572. Sci Transl Med. 2020. PMID: 32434848 Free PMC article.
Thalamic activity that drives visual cortical plasticity.
Linden ML, Heynen AJ, Haslinger RH, Bear MF. Linden ML, et al. Among authors: heynen aj. Nat Neurosci. 2009 Apr;12(4):390-2. doi: 10.1038/nn.2284. Epub 2009 Mar 1. Nat Neurosci. 2009. PMID: 19252494 Free PMC article.
23 results