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Page 1
Tax1bp1 enhances bacterial virulence and promotes inflammatory responses during Mycobacterium tuberculosis infection of alveolar macrophages.
Chin J, Abeydeera N, Repasy T, Rivera-Lugo R, Mitchell G, Nguyen VQ, Zheng W, Richards A, Swaney DL, Krogan NJ, Ernst JD, Cox JS, Budzik JM. Chin J, et al. Among authors: krogan nj. bioRxiv [Preprint]. 2024 Dec 16:2024.12.16.628616. doi: 10.1101/2024.12.16.628616. bioRxiv. 2024. PMID: 39763950 Free PMC article. Preprint.
Central control of dynamic gene circuits governs T cell rest and activation.
Arce MM, Umhoefer JM, Arang N, Kasinathan S, Freimer JW, Steinhart Z, Shen H, Pham MTN, Ota M, Wadhera A, Dajani R, Dorovskyi D, Chen YY, Liu Q, Zhou Y, Swaney DL, Obernier K, Shy BR, Carnevale J, Satpathy AT, Krogan NJ, Pritchard JK, Marson A. Arce MM, et al. Among authors: krogan nj. Nature. 2025 Jan;637(8047):930-939. doi: 10.1038/s41586-024-08314-y. Epub 2024 Dec 11. Nature. 2025. PMID: 39663454 Free PMC article.
HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma.
Turnham RE, Pitea A, Jang GM, Xu Z, Lim HC, Choi AL, Von Dollen J, Levin RS, Webber JT, McCarthy E, Hu J, Li X, Che L, Singh A, Yoon A, Chan G, Kelley RK, Swaney DL, Zhang W, Bandyopadhyay S, Theis FJ, Eckhardt M, Chen X, Shokat KM, Ideker T, Krogan NJ, Gordan JD. Turnham RE, et al. Among authors: krogan nj. Cancer Res. 2024 Dec 9. doi: 10.1158/0008-5472.CAN-24-0456. Online ahead of print. Cancer Res. 2024. PMID: 39652575
SARS-CoV-2 evolution balances conflicting roles of N protein phosphorylation.
Syed AM, Ciling A, Chen IP, Carlson CR, Adly AN, Martin HS, Taha TY, Khalid MM, Price N, Bouhaddou M, Ummadi MR, Moen JM, Krogan NJ, Morgan DO, Ott M, Doudna JA. Syed AM, et al. Among authors: krogan nj. PLoS Pathog. 2024 Nov 21;20(11):e1012741. doi: 10.1371/journal.ppat.1012741. eCollection 2024 Nov. PLoS Pathog. 2024. PMID: 39571001 Free PMC article.
Protocol for mapping differential protein-protein interaction networks using affinity purification-mass spectrometry.
Kaushal P, Ummadi MR, Jang GM, Delgado Y, Makanani SK, Alba K, Winters DM, Blanc SF, Xu J, Polacco B, Zhou Y, Stevenson E, Eckhardt M, Zuliani-Alvarez L, Kaake R, Swaney DL, Krogan NJ, Bouhaddou M. Kaushal P, et al. Among authors: krogan nj. STAR Protoc. 2024 Dec 20;5(4):103286. doi: 10.1016/j.xpro.2024.103286. Epub 2024 Nov 2. STAR Protoc. 2024. PMID: 39488835 Free PMC article.
MerlinS13 phosphorylation regulates meningioma Wnt signaling and magnetic resonance imaging features.
Eaton CD, Avalos L, Liu SJ, Chen Z, Zakimi N, Casey-Clyde T, Bisignano P, Lucas CG, Stevenson E, Choudhury A, Vasudevan HN, Magill ST, Young JS, Krogan NJ, Villanueva-Meyer JE, Swaney DL, Raleigh DR. Eaton CD, et al. Among authors: krogan nj. Nat Commun. 2024 Sep 9;15(1):7873. doi: 10.1038/s41467-024-52284-8. Nat Commun. 2024. PMID: 39251601 Free PMC article.
Fibrin drives thromboinflammation and neuropathology in COVID-19.
Ryu JK, Yan Z, Montano M, Sozmen EG, Dixit K, Suryawanshi RK, Matsui Y, Helmy E, Kaushal P, Makanani SK, Deerinck TJ, Meyer-Franke A, Rios Coronado PE, Trevino TN, Shin MG, Tognatta R, Liu Y, Schuck R, Le L, Miyajima H, Mendiola AS, Arun N, Guo B, Taha TY, Agrawal A, MacDonald E, Aries O, Yan A, Weaver O, Petersen MA, Meza Acevedo R, Alzamora MDPS, Thomas R, Traglia M, Kouznetsova VL, Tsigelny IF, Pico AR, Red-Horse K, Ellisman MH, Krogan NJ, Bouhaddou M, Ott M, Greene WC, Akassoglou K. Ryu JK, et al. Among authors: krogan nj. Nature. 2024 Sep;633(8031):905-913. doi: 10.1038/s41586-024-07873-4. Epub 2024 Aug 28. Nature. 2024. PMID: 39198643 Free PMC article.
The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2.
Suryawanshi RK, Jaishankar P, Correy GJ, Rachman MM, O'Leary PC, Taha TY, Zapatero-Belinchón FJ, McCavittMalvido M, Doruk YU, Stevens MGV, Diolaiti ME, Jogalekar MP, Richards AL, Montano M, Rosecrans J, Matthay M, Togo T, Gonciarz RL, Gopalkrishnan S, Neitz RJ, Krogan NJ, Swaney DL, Shoichet BK, Ott M, Renslo AR, Ashworth A, Fraser JS. Suryawanshi RK, et al. Among authors: krogan nj. bioRxiv [Preprint]. 2024 Aug 29:2024.08.08.606661. doi: 10.1101/2024.08.08.606661. bioRxiv. 2024. PMID: 39149230 Free PMC article. Preprint.
Interactome of the HIV-1 proteome and human host RNA.
Schynkel T, Snippenberg WV, Verniers K, Jang GM, Krogan NJ, Mestdagh P, Vandekerckhove L, Trypsteen W. Schynkel T, et al. Among authors: krogan nj. EMBO Rep. 2024 Sep;25(9):4078-4090. doi: 10.1038/s44319-024-00222-6. Epub 2024 Aug 9. EMBO Rep. 2024. PMID: 39122863 Free PMC article.
374 results