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Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids.
Barnhart S, Shimizu-Albergine M, Kedar E, Kothari V, Shao B, Krueger M, Hsu CC, Tang J, Kanter JE, Kramer F, Djukovic D, Pascua V, Loo YM, Colonna L, Van den Bogaerde SJ, An J, Gale M Jr, Reue K, Fisher EA, Gharib SA, Elkon KB, Bornfeldt KE. Barnhart S, et al. Among authors: bornfeldt ke. J Lipid Res. 2024 Dec 14;66(1):100730. doi: 10.1016/j.jlr.2024.100730. Online ahead of print. J Lipid Res. 2024. PMID: 39675509 Free article.
APOA2 increases cholesterol efflux capacity to plasma HDL by displacing the C-terminus of resident APOA1.
Sarkar S, Morris J, You Y, Sexmith H, Street SE, Thibert SM, Attah IK, Hutchinson Bunch CM, Novikova IV, Evans JE, Shah AS, Gordon SM, Segrest JP, Bornfeldt KE, Vaisar T, Heinecke JW, Davidson WS, Melchior JT. Sarkar S, et al. Among authors: bornfeldt ke. J Lipid Res. 2024 Dec;65(12):100686. doi: 10.1016/j.jlr.2024.100686. Epub 2024 Oct 28. J Lipid Res. 2024. PMID: 39490930 Free PMC article.
Imbalance of APOB Lipoproteins and Large HDL in Type 1 Diabetes Drives Atherosclerosis.
Kothari V, Ho TWW, Cabodevilla AG, He Y, Kramer F, Shimizu-Albergine M, Kanter JE, Snell-Bergeon J, Fisher EA, Shao B, Heinecke JW, Wobbrock JO, Lee WL, Goldberg IJ, Vaisar T, Bornfeldt KE. Kothari V, et al. Among authors: bornfeldt ke. Circ Res. 2024 Jul 5;135(2):335-349. doi: 10.1161/CIRCRESAHA.123.323100. Epub 2024 Jun 3. Circ Res. 2024. PMID: 38828596 Free PMC article.
174 results