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Page 1
Radiological markers of CSF α-synuclein aggregation in Parkinson's disease patients.
Droby A, Yoffe-Vasiliev A, Atias D, Fraser KB, Mabrouk OS, Omer N, Bar-Shira A, Gana-Weisz M, Goldstein O, Artzi M, Ben Bashat D, Alcalay RN, Orr-Urtreger A, Shirvan JC, Cedarbaum JM, Giladi N, Mirelman A, Thaler A. Droby A, et al. Among authors: alcalay rn. NPJ Parkinsons Dis. 2025 Jan 3;11(1):7. doi: 10.1038/s41531-024-00854-4. NPJ Parkinsons Dis. 2025. PMID: 39753572 Free PMC article.
Impact of dopamine deficiency and REM sleep behavior disorder on cognition in early neuronal synuclein disease with hyposmia.
Weintraub D, Nair AR, Kurth R, Brumm MC, York MK, Dobkin R, Marek K, Tanner C, Simuni T, Siderowf A, Galasko D, Chahine LM, Coffey C, Merchant K, Poston KL, Foroud T, Mollenhauer B, Brown EG, Kieburtz K, Frasier M, Sherer T, Chowdhury S, Alcalay RN, Videnovic A; Parkinson’s Progression Markers Initiative. Weintraub D, et al. Among authors: alcalay rn. medRxiv [Preprint]. 2024 Dec 13:2024.12.12.24318917. doi: 10.1101/2024.12.12.24318917. medRxiv. 2024. PMID: 39711699 Free PMC article. Preprint.
Correction: The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons.
Jones-Tabah J, He K, Karpilovsky N, Senkevich K, Deyab G, Pietrantonio I, Goiran T, Cousineau Y, Nikanorova D, Goldsmith T, Del Cid Pellitero E, Chen CX, Luo W, You Z, Abdian N, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Fahn S, Waters C, Monchi O, Dauvilliers Y, Dupré N, Miliukhina I, Timofeeva A, Emelyanov A, Pchelina S, Greenbaum L, Hassin-Baer S, Alcalay RN, Milnerwood A, Durcan TM, Gan-Or Z, Fon EA. Jones-Tabah J, et al. Among authors: alcalay rn. Mol Neurodegener. 2024 Dec 18;19(1):94. doi: 10.1186/s13024-024-00791-z. Mol Neurodegener. 2024. PMID: 39696367 Free PMC article. No abstract available.
PINK1 is a target of T cell responses in Parkinson's disease.
Williams GP, Freuchet A, Michaelis T, Frazier A, Tran NK, Rodrigues Lima-Junior J, Phillips EJ, Mallal SA, Litvan I, Goldman JG, Alcalay RN, Sidney J, Sulzer D, Sette A, Lindestam Arlehamn CS. Williams GP, et al. Among authors: alcalay rn. J Clin Invest. 2024 Dec 17:e180478. doi: 10.1172/JCI180478. Online ahead of print. J Clin Invest. 2024. PMID: 39688918 Free article.
Return of individual research results to participants with and at risk for Parkinson's disease.
Lettenberger SE, Hartman EA, Tam K, Auinger P, Pawlik ME, Wilson R, Banda ET, Valdovinos B, Kinel D, Alcalay RN, Dorsey ER, Norcliffe-Kaufmann L, Sharma S, Holloway RG, Schneider RB. Lettenberger SE, et al. Among authors: alcalay rn. J Clin Transl Sci. 2024 Oct 15;8(1):e164. doi: 10.1017/cts.2024.616. eCollection 2024. J Clin Transl Sci. 2024. PMID: 39619068 Free PMC article.
The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons.
Jones-Tabah J, He K, Karpilovsky N, Senkevich K, Deyab G, Pietrantonio I, Goiran T, Cousineau Y, Nikanorova D, Goldsmith T, Del Cid Pellitero E, Chen CX, Luo W, You Z, Abdian N, Ahmad J, Ruskey JA, Asayesh F, Spiegelman D, Fahn S, Waters C, Monchi O, Dauvilliers Y, Dupré N, Miliukhina I, Timofeeva A, Emelyanov A, Pchelina S, Greenbaum L, Hassin-Baer S, Alcalay RN, Milnerwood A, Durcan TM, Gan-Or Z, Fon EA. Jones-Tabah J, et al. Among authors: alcalay rn. Mol Neurodegener. 2024 Nov 25;19(1):88. doi: 10.1186/s13024-024-00779-9. Mol Neurodegener. 2024. PMID: 39587654 Free PMC article.
Sensitivity and specificity of a seed amplification assay for diagnosis of multiple system atrophy: a multicentre cohort study.
Ma Y, Farris CM, Weber S, Schade S, Nguyen H, Pérez-Soriano A, Giraldo DM, Fernández M, Soto M, Cámara A, Painous C, Muñoz E, Valldeoriola F, Martí MJ, Clarimon J, Kallunki P, Ma TC, Alcalay RN, Gomes BF, Blennow K, Zetterberg H, Constantinescu J, Mengel D, Kadam V, Parchi P, Brockmann K, Tropea TF, Siderowf A, Synofzik M, Kang UJ, Compta Y, Svenningsson P, Mollenhauer B, Concha-Marambio L. Ma Y, et al. Among authors: alcalay rn. Lancet Neurol. 2024 Dec;23(12):1225-1237. doi: 10.1016/S1474-4422(24)00395-8. Lancet Neurol. 2024. PMID: 39577923
Exome sequencing in Asian populations identifies low-frequency and rare coding variation influencing Parkinson's disease risk.
Chew EG, Liu Z, Li Z, Chung SJ, Lian MM, Tandiono M, Heng YJ, Ng EY, Tan LC, Chng WL, Tan TJ, Peh EK, Ho YS, Chen XY, Lim EY, Chang CH, Leong JJ, Peh TX, Chan LL, Chao Y, Au WL, Prakash KM, Lim JL, Tay YW, Mok V, Chan AY, Lin JJ, Jeon BS, Song K, Tham CC, Pang CP, Ahn J, Park KH, Wiggs JL, Aung T, Tan AH, Ahmad Annuar A, Makarious MB, Blauwendraat C, Nalls MA, Robak LA, Alcalay RN, Gan-Or Z, Reynolds R, Lim SY, Xia Y, Khor CC, Tan EK, Wang Z, Foo JN. Chew EG, et al. Among authors: alcalay rn. Nat Aging. 2024 Nov 21. doi: 10.1038/s43587-024-00760-7. Online ahead of print. Nat Aging. 2024. PMID: 39572736
247 results