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Co-isolation of human donor eye cells and development of oncogene-mutated melanocytes to study uveal melanoma.
Chen Y, Jin E, Abdouh M, Bonneil É, Jimenez Cruz DA, Tsering T, Zhou Q, Fuentes-Rodriguez A, Bartolomucci A, Goyeneche A, Landreville S, Burnier MN, Burnier JV. Chen Y, et al. BMC Biol. 2025 Jan 21;23(1):16. doi: 10.1186/s12915-025-02118-w. BMC Biol. 2025. PMID: 39838458
NCM growth and behavior were characterized under different culture conditions (i.e., supplementation with serum and 12-O-tetradecanoylphorbol-13-acetate) to determine optimized protocols. Particularly, Matrigel coating induced spheroid growth under certain coating thicknes …
NCM growth and behavior were characterized under different culture conditions (i.e., supplementation with serum and 12-O-tetradecanoy …
First autochthonous case of Opisthorchis felineus in Austria.
Kulmer LM, Unterköfler MS, Vali Y, Schwendenwein I, Luckschander-Zeller N. Kulmer LM, et al. Parasit Vectors. 2025 Jan 21;18(1):20. doi: 10.1186/s13071-025-06659-5. Parasit Vectors. 2025. PMID: 39838451
RESULTS: The cat showed increased liver enzyme activities, hyperbilirubinemia and hyperammonemia consistent with the suspected diagnosis of cholangitis with consecutive hepatoencephalopathy. Eggs of O. felineus were detected by routine cytological examination of bile smear …
RESULTS: The cat showed increased liver enzyme activities, hyperbilirubinemia and hyperammonemia consistent with the suspected diagnosis of …
Multi-gene precision editing tool using CRISPR-Cas12a/Cpf1 system in Ogataea polymorpha.
Hou S, Yang S, Bai W. Hou S, et al. Microb Cell Fact. 2025 Jan 21;24(1):28. doi: 10.1186/s12934-025-02654-8. Microb Cell Fact. 2025. PMID: 39838422
RESULTS: In this study, we developed an efficient CRISPR-Cpf1-mediated genome editing system in O. polymorpha that exhibited high editing efficiency for single gene (98.1 1.7%), duplex genes (93.9 2.4%), and triplex genes (94.0 6.0%). ...Furthermore, using this developed C …
RESULTS: In this study, we developed an efficient CRISPR-Cpf1-mediated genome editing system in O. polymorpha that exhibited high edi …
Robust circulating microRNA signature for the diagnosis and early detection of pancreatobiliary cancer.
Mitsunaga S, Ikeda M, Ueno M, Kobayshi S, Tsuda M, Miki I, Kuwahara T, Hara K, Takayama Y, Matsunaga Y, Hanada K, Shimizu A, Yoshida H, Nomoto T, Takahashi K, Iwamoto H, Iwama H, Hatano E, Nakata K, Nakamura M, Sudo H, Takizawa S, Ochiai A. Mitsunaga S, et al. BMC Med. 2025 Jan 21;23(1):23. doi: 10.1186/s12916-025-03849-x. BMC Med. 2025. PMID: 39838364
1,170,175 results
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