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Page 1
Dual inhibition of airway inflammation and fibrosis by common β cytokine receptor blockade.
Wang H, Yip KH, Keam SP, Vlahos R, Nichol K, Wark P, Toubia J, Kral AC, Cildir G, Pant H, Hercus TR, Wilson N, Owczarek C, Lopez AF, Bozinovski S, Tumes DJ. Wang H, et al. Among authors: hercus tr. J Allergy Clin Immunol. 2024 Mar;153(3):672-683.e6. doi: 10.1016/j.jaci.2023.10.021. Epub 2023 Nov 4. J Allergy Clin Immunol. 2024. PMID: 37931708 Free article.
Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia.
Kan WL, Dhagat U, Kaufmann KB, Hercus TR, Nero TL, Zeng AGX, Toubia J, Barry EF, Broughton SE, Gomez GA, Benard BA, Dottore M, Cheung Tung Shing KS, Boutzen H, Samaraweera SE, Simpson KJ, Jin L, Goodall GJ, Begley CG, Thomas D, Ekert PG, Tvorogov D, D'Andrea RJ, Dick JE, Parker MW, Lopez AF. Kan WL, et al. Among authors: hercus tr. Cancer Discov. 2023 Aug 4;13(8):1922-1947. doi: 10.1158/2159-8290.CD-22-1396. Cancer Discov. 2023. PMID: 37191437 Free PMC article.
Messing with βc: A unique receptor with many goals.
Kan WL, Cheung Tung Shing KS, Nero TL, Hercus TR, Tvorogov D, Parker MW, Lopez AF. Kan WL, et al. Among authors: hercus tr. Semin Immunol. 2021 Apr;54:101513. doi: 10.1016/j.smim.2021.101513. Epub 2021 Nov 24. Semin Immunol. 2021. PMID: 34836771 Review.
Targeting the Human βc Receptor Inhibits Contact Dermatitis in a Transgenic Mouse Model.
Yip KH, McKenzie D, Ramshaw HS, Chao J, McClure BJ, Raquet E, Kraushaar T, Röder J, Maxwell M, Alhamdoosh M, Hammet A, Fong JH, Zeglinski K, Monaghan K, Pant H, Grimbaldeston MA, Vairo G, Wilson NJ, Owczarek CM, Hercus TR, Lopez AF, Tumes DJ. Yip KH, et al. Among authors: hercus tr. J Invest Dermatol. 2022 Apr;142(4):1103-1113.e11. doi: 10.1016/j.jid.2021.07.183. Epub 2021 Sep 17. J Invest Dermatol. 2022. PMID: 34537191 Free article.
Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis.
Tvorogov D, Thomas D, Liau NPD, Dottore M, Barry EF, Lathi M, Kan WL, Hercus TR, Stomski F, Hughes TP, Tergaonkar V, Parker MW, Ross DM, Majeti R, Babon JJ, Lopez AF. Tvorogov D, et al. Among authors: hercus tr. Sci Adv. 2018 Nov 28;4(11):eaat3834. doi: 10.1126/sciadv.aat3834. eCollection 2018 Nov. Sci Adv. 2018. PMID: 30498775 Free PMC article.
A dual role for the N-terminal domain of the IL-3 receptor in cell signalling.
Broughton SE, Hercus TR, Nero TL, Kan WL, Barry EF, Dottore M, Cheung Tung Shing KS, Morton CJ, Dhagat U, Hardy MP, Wilson NJ, Downton MT, Schieber C, Hughes TP, Lopez AF, Parker MW. Broughton SE, et al. Among authors: hercus tr. Nat Commun. 2018 Jan 26;9(1):386. doi: 10.1038/s41467-017-02633-7. Nat Commun. 2018. PMID: 29374162 Free PMC article.
37 results