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Discovery of 2-(6-{[(1R,2R)-2-hydroxycyclohexyl]amino}-4,5-dimethylpyridazin-3-yl)-5-(trifluoromethyl)phenol (ASP0965): A potent, orally active and brain-penetrable NLRP3 inflammasome inhibitor with a novel scaffold for the treatment of α-synucleinopathy.
Inagaki Y, Kamikubo T, Kuriwaki I, Watanabe J, Yamaki S, Iida M, Tomita K, Kakefuda K, Kurokawa J, Kiso T, Saba K, Koike T. Inagaki Y, et al. Among authors: kamikubo t. Bioorg Med Chem. 2024 Dec 12;118:118042. doi: 10.1016/j.bmc.2024.118042. Online ahead of print. Bioorg Med Chem. 2024. PMID: 39742857
Benefits of Early Mobilization After Pediatric Liver Transplantation.
Tsuboi N, Hiratsuka M, Kaneko S, Nishimura N, Nakagawa S, Kasahara M, Kamikubo T. Tsuboi N, et al. Among authors: kamikubo t. Pediatr Crit Care Med. 2019 Feb;20(2):e91-e97. doi: 10.1097/PCC.0000000000001815. Pediatr Crit Care Med. 2019. PMID: 30489487
Early Mobilization after Pediatric Liver Transplantation.
Tsuboi N, Nozaki H, Ishida Y, Kanazawa I, Inamoto M, Hayashi K, Nishimura N, Nakagawa S, Kasahara M, Kamikubo T. Tsuboi N, et al. Among authors: kamikubo t. J Pediatr Intensive Care. 2017 Sep;6(3):199-205. doi: 10.1055/s-0036-1593387. Epub 2016 Sep 21. J Pediatr Intensive Care. 2017. PMID: 31073448 Free PMC article.
49 results