Wu J - Search Results

1

A novel therapeutic strategy for leukopenia: Miltefosine activates the Ras/MEK/ERK pathway to promote neutrophil differentiation.

Li Q, He S, Li Z, Liu S, Mei X, Qi X, Qiao G, Luo J, Shen H, Zeng J, Huang F, Gong S, Chen Z, Wu J, Wang L. Li Q, et al. Among authors: wu j. Biochem Biophys Res Commun. 2025 Feb;746:151239. doi: 10.1016/j.bbrc.2024.151239. Epub 2024 Dec 27. Biochem Biophys Res Commun. 2025. PMID: 39742788

2

A Novel Antithrombocytopenia Agent, Rhizoma cibotii, Promotes Megakaryopoiesis and Thrombopoiesis through the PI3K/AKT, MEK/ERK, and JAK2/STAT3 Signaling Pathways.

Chen W, Zhu L, Wang L, Zeng J, Wen M, Xu X, Zou L, Huang F, Huang Q, Qin D, Mei Q, Yang J, Wang Q, Wu J. Chen W, et al. Among authors: wu j. Int J Mol Sci. 2022 Nov 14;23(22):14060. doi: 10.3390/ijms232214060. Int J Mol Sci. 2022. PMID: 36430539 Free PMC article.

3

Targeting a thrombopoietin-independent strategy in the discovery of a novel inducer of megakaryocytopoiesis, DMAG, for the treatment of thrombocytopenia.

Wang L, Liu S, Luo J, Mo Q, Ran M, Zhang T, Li X, Zou W, Mei Q, Chen J, Yang J, Zeng J, Huang F, Wu A, Zhang C, Wu J. Wang L, et al. Among authors: wu a, wu j. Haematologica. 2023 May 1;108(5):1394-1411. doi: 10.3324/haematol.2022.282209. Haematologica. 2023. PMID: 36546424 Free PMC article.

4

The combination of machine learning and transcriptomics reveals a novel megakaryopoiesis inducer, MO-A, that promotes thrombopoiesis by activating FGF1/FGFR1/PI3K/Akt/NF-κB signaling.

Zhang T, Mo Q, Jiang N, Wu Y, Yang X, Chen W, Li Q, Yang S, Yang J, Zeng J, Huang F, Huang Q, Luo J, Wu J, Wang L. Zhang T, et al. Among authors: wu y, wu j. Eur J Pharmacol. 2023 Apr 5;944:175604. doi: 10.1016/j.ejphar.2023.175604. Epub 2023 Feb 18. Eur J Pharmacol. 2023. PMID: 36804544

5

Elucidation of the molecular mechanism of Sanguisorba Officinalis L. against leukopenia based on network pharmacology.

Wang L, Li H, Shen X, Zeng J, Yue L, Lin J, Yang J, Zou W, Li Y, Qin D, Wu A, Wu J. Wang L, et al. Among authors: wu a, wu j. Biomed Pharmacother. 2020 Dec;132:110934. doi: 10.1016/j.biopha.2020.110934. Epub 2020 Nov 1. Biomed Pharmacother. 2020. PMID: 33254437 Free article.

6

Whole transcriptome sequencing and integrated network analysis elucidates the effects of 3,8-Di-O-methylellagic acid 2-O-glucoside derived from Sanguisorba offcinalis L., a novel differentiation inducer on erythroleukemia cells.

Long W, Liu S, Li XX, Shen X, Zeng J, Luo JS, Li KR, Wu AG, Yu L, Qin DL, Hu GQ, Yang J, Wu JM. Long W, et al. Among authors: wu jm, wu ag. Pharmacol Res. 2021 Apr;166:105491. doi: 10.1016/j.phrs.2021.105491. Epub 2021 Feb 12. Pharmacol Res. 2021. PMID: 33582247

7

DMAG, a novel countermeasure for the treatment of thrombocytopenia.

Lin J, Zeng J, Liu S, Shen X, Jiang N, Wu YS, Li H, Wang L, Wu JM. Lin J, et al. Among authors: wu jm, wu ys. Mol Med. 2021 Nov 27;27(1):149. doi: 10.1186/s10020-021-00404-1. Mol Med. 2021. PMID: 34837956 Free PMC article.

8

Discovery of a novel megakaryopoiesis enhancer, ingenol, promoting thrombopoiesis through PI3K-Akt signaling independent of thrombopoietin.

Wang L, Zhang T, Liu S, Mo Q, Jiang N, Chen Q, Yang J, Han YW, Chen JP, Huang FH, Li H, Zhou J, Luo JS, Wu JM. Wang L, et al. Among authors: wu jm. Pharmacol Res. 2022 Mar;177:106096. doi: 10.1016/j.phrs.2022.106096. Epub 2022 Jan 22. Pharmacol Res. 2022. PMID: 35077844

9

UHPLC/MS-Based Serum Metabolomics Reveals the Mechanism of Radiation-Induced Thrombocytopenia in Mice.

Xiong L, Wang L, Zhang T, Ye X, Huang F, Huang Q, Huang X, Wu J, Zeng J. Xiong L, et al. Among authors: wu j. Int J Mol Sci. 2022 Jul 20;23(14):7978. doi: 10.3390/ijms23147978. Int J Mol Sci. 2022. PMID: 35887324 Free PMC article.

10

Caulis Polygoni Multiflori Accelerates Megakaryopoiesis and Thrombopoiesis via Activating PI3K/Akt and MEK/ERK Signaling Pathways.

Yang X, Wang L, Zeng J, Wu A, Qin M, Wen M, Zhang T, Chen W, Mei Q, Qin D, Yang J, Jiang Y, Wu J. Yang X, et al. Among authors: wu a, wu j. Pharmaceuticals (Basel). 2022 Sep 28;15(10):1204. doi: 10.3390/ph15101204. Pharmaceuticals (Basel). 2022. PMID: 36297316 Free PMC article.

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