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Page 1
Self-Delivering RNAi Compounds for Reduction of Hyperpigmentation.
Maxwell M, Holton K, Looby RJ, Byrne M, Cardia J. Maxwell M, et al. Among authors: byrne m. Clin Cosmet Investig Dermatol. 2024 Dec 27;17:3033-3044. doi: 10.2147/CCID.S498987. eCollection 2024. Clin Cosmet Investig Dermatol. 2024. PMID: 39741580 Free PMC article.
Stereochemistry Enhances Potency, Efficacy, and Durability of Malat1 Antisense Oligonucleotides In Vitro and In Vivo in Multiple Species.
Byrne M, Vathipadiekal V, Apponi L, Iwamoto N, Kandasamy P, Longo K, Liu F, Looby R, Norwood L, Shah A, Shelke JD, Shivalila C, Yang H, Yin Y, Guo L, Bowman K, Vargeese C. Byrne M, et al. Transl Vis Sci Technol. 2021 Jan 12;10(1):23. doi: 10.1167/tvst.10.1.23. eCollection 2021 Jan. Transl Vis Sci Technol. 2021. PMID: 33510962 Free PMC article.
Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides.
Monian P, Shivalila C, Lu G, Shimizu M, Boulay D, Bussow K, Byrne M, Bezigian A, Chatterjee A, Chew D, Desai J, Favaloro F, Godfrey J, Hoss A, Iwamoto N, Kawamoto T, Kumarasamy J, Lamattina A, Lindsey A, Liu F, Looby R, Marappan S, Metterville J, Murphy R, Rossi J, Pu T, Bhattarai B, Standley S, Tripathi S, Yang H, Yin Y, Yu H, Zhou C, Apponi LH, Kandasamy P, Vargeese C. Monian P, et al. Among authors: byrne m. Nat Biotechnol. 2022 Jul;40(7):1093-1102. doi: 10.1038/s41587-022-01225-1. Epub 2022 Mar 7. Nat Biotechnol. 2022. PMID: 35256816
Preclinical evaluation of stereopure antisense oligonucleotides for allele-selective lowering of mutant HTT.
Iwamoto N, Liu Y, Frank-Kamenetsky M, Maguire A, Tseng WC, Taborn K, Kothari N, Akhtar A, Bowman K, Shelke JD, Lamattina A, Hu XS, Jang HG, Kandasamy P, Liu F, Longo K, Looby R, Meena, Metterville J, Pan Q, Purcell-Estabrook E, Shimizu M, Prakasha PS, Standley S, Upadhyay H, Yang H, Yin Y, Zhao A, Francis C, Byrne M, Dale E, Verdine GL, Vargeese C. Iwamoto N, et al. Among authors: byrne m. Mol Ther Nucleic Acids. 2024 Jun 11;35(3):102246. doi: 10.1016/j.omtn.2024.102246. eCollection 2024 Sep 10. Mol Ther Nucleic Acids. 2024. PMID: 39027419 Free PMC article.
Impact of guanidine-containing backbone linkages on stereopure antisense oligonucleotides in the CNS.
Kandasamy P, Liu Y, Aduda V, Akare S, Alam R, Andreucci A, Boulay D, Bowman K, Byrne M, Cannon M, Chivatakarn O, Shelke JD, Iwamoto N, Kawamoto T, Kumarasamy J, Lamore S, Lemaitre M, Lin X, Longo K, Looby R, Marappan S, Metterville J, Mohapatra S, Newman B, Paik IH, Patil S, Purcell-Estabrook E, Shimizu M, Shum P, Standley S, Taborn K, Tripathi S, Yang H, Yin Y, Zhao X, Dale E, Vargeese C. Kandasamy P, et al. Among authors: byrne m. Nucleic Acids Res. 2022 Jun 10;50(10):5401-5423. doi: 10.1093/nar/gkac037. Nucleic Acids Res. 2022. PMID: 35106589 Free PMC article.
Impact of stereopure chimeric backbone chemistries on the potency and durability of gene silencing by RNA interference.
Liu W, Iwamoto N, Marappan S, Luu K, Tripathi S, Purcell-Estabrook E, Shelke JD, Shah H, Lamattina A, Pan Q, Schrand B, Favaloro F, Bedekar M, Chatterjee A, Desai J, Kawamoto T, Lu G, Metterville J, Samaraweera M, Prakasha PS, Yang H, Yin Y, Yu H, Giangrande PH, Byrne M, Kandasamy P, Vargeese C. Liu W, et al. Among authors: byrne m. Nucleic Acids Res. 2023 May 22;51(9):4126-4147. doi: 10.1093/nar/gkad268. Nucleic Acids Res. 2023. PMID: 37070173 Free PMC article.
Global meta-analysis shows action is needed to halt genetic diversity loss.
Shaw RE, Farquharson KA, Bruford MW, Coates DJ, Elliott CP, Mergeay J, Ottewell KM, Segelbacher G, Hoban S, Hvilsom C, Pérez-Espona S, Ruņģis D, Aravanopoulos F, Bertola LD, Cotrim H, Cox K, Cubric-Curik V, Ekblom R, Godoy JA, Konopiński MK, Laikre L, Russo IM, Veličković N, Vergeer P, Vilà C, Brajkovic V, Field DL, Goodall-Copestake WP, Hailer F, Hopley T, Zachos FE, Alves PC, Biedrzycka A, Binks RM, Buiteveld J, Buzan E, Byrne M, Huntley B, Iacolina L, Keehnen NLP, Klinga P, Kopatz A, Kurland S, Leonard JA, Manfrin C, Marchesini A, Millar MA, Orozco-terWengel P, Ottenburghs J, Posledovich D, Spencer PB, Tourvas N, Unuk Nahberger T, van Hooft P, Verbylaite R, Vernesi C, Grueber CE. Shaw RE, et al. Among authors: byrne m. Nature. 2025 Jan 29. doi: 10.1038/s41586-024-08458-x. Online ahead of print. Nature. 2025. PMID: 39880948
Using augmented reality to deliver cue exposure treatment for smoking cessation: App usability findings and protocol for a randomized controlled trial.
Poudel R, Dougan SO, Yates H, Sawyer L, Martinez U, Brandon KO, Sutton SK, Vidrine DJ, Ritterband LM, Wiseman KP, Vickerman KA, Turner K, Byrne MM, Yang MJ, Horta M, Brandon TH, Vinci C. Poudel R, et al. Among authors: byrne mm. Contemp Clin Trials. 2025 Jan 27;150:107827. doi: 10.1016/j.cct.2025.107827. Online ahead of print. Contemp Clin Trials. 2025. PMID: 39880329
Revered and Reviled: The Plight of the Vanishing Sea Cucumbers.
Mercier A, Purcell SW, Montgomery EM, Kinch J, Byrne M, Hamel JF. Mercier A, et al. Among authors: byrne m. Ann Rev Mar Sci. 2025 Jan;17(1):115-142. doi: 10.1146/annurev-marine-032123-025441. Ann Rev Mar Sci. 2025. PMID: 39819554 Free article. Review.
2,350 results