Tu Z - Search Results

1

Synthesis and in vitro evaluation of novel compounds and discovery of a promising iodine-125 radioligand for purinergic P2X7 receptor (P2X7R).

Qiu L, Wang J, Tewari M, Rensing DT, Egan TM, Perlmutter JS, Tu Z. Qiu L, et al. Among authors: tu z. Bioorg Med Chem. 2024 Dec 22;118:118054. doi: 10.1016/j.bmc.2024.118054. Online ahead of print. Bioorg Med Chem. 2024. PMID: 39740572 Free article.

2

Radiosynthesis and evaluation of a fluorine-18 labeled radioligand targeting vesicular acetylcholine transporter.

Yue X, Luo Z, Liu H, Kaneshige K, Parsons SM, Perlmutter JS, Tu Z. Yue X, et al. Among authors: tu z. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3425-3430. doi: 10.1016/j.bmcl.2018.09.030. Epub 2018 Sep 24. Bioorg Med Chem Lett. 2018. PMID: 30274694 Free PMC article.

3

Discovery of a Promising Fluorine-18 Positron Emission Tomography Radiotracer for Imaging Sphingosine-1-Phosphate Receptor 1 in the Brain.

Qiu L, Jiang H, Zhou C, Wang J, Yu Y, Zhao H, Huang T, Gropler R, Perlmutter JS, Benzinger TLS, Tu Z. Qiu L, et al. Among authors: tu z. J Med Chem. 2023 Apr 13;66(7):4671-4688. doi: 10.1021/acs.jmedchem.2c01752. Epub 2023 Mar 16. J Med Chem. 2023. PMID: 36926861 Free PMC article.

4

Synthesis and in vitro evaluation of new TRPV4 ligands and biodistribution study of an ¹¹C-labeled radiotracer in rodents.

Qiu L, Du L, Liang Q, Hu H, Tu Z. Qiu L, et al. Among authors: tu z. Bioorg Med Chem Lett. 2020 Nov 15;30(22):127573. doi: 10.1016/j.bmcl.2020.127573. Epub 2020 Sep 24. Bioorg Med Chem Lett. 2020. PMID: 32980513 Free PMC article.

5

Radiosynthesis and in vivo evaluation of [11C]MP-10 as a PET probe for imaging PDE10A in rodent and non-human primate brain.

Tu Z, Fan J, Li S, Jones LA, Cui J, Padakanti PK, Xu J, Zeng D, Shoghi KI, Perlmutter JS, Mach RH. Tu Z, et al. Bioorg Med Chem. 2011 Mar 1;19(5):1666-73. doi: 10.1016/j.bmc.2011.01.032. Epub 2011 Jan 22. Bioorg Med Chem. 2011. PMID: 21315609 Free PMC article.

6

Heteroaromatic and aniline derivatives of piperidines as potent ligands for vesicular acetylcholine transporter.

Li J, Zhang X, Zhang Z, Padakanti PK, Jin H, Cui J, Li A, Zeng D, Rath NP, Flores H, Perlmutter JS, Parsons SM, Tu Z. Li J, et al. Among authors: tu z. J Med Chem. 2013 Aug 8;56(15):6216-33. doi: 10.1021/jm400664x. Epub 2013 Jul 18. J Med Chem. 2013. PMID: 23802889 Free PMC article.

7

Radiosyntheses and in vivo evaluation of carbon-11 PET tracers for PDE10A in the brain of rodent and nonhuman primate.

Fan J, Zhang X, Li J, Jin H, Padakanti PK, Jones LA, Flores HP, Su Y, Perlmutter JS, Tu Z. Fan J, et al. Among authors: tu z. Bioorg Med Chem. 2014 May 1;22(9):2648-54. doi: 10.1016/j.bmc.2014.03.028. Epub 2014 Mar 26. Bioorg Med Chem. 2014. PMID: 24721831 Free PMC article.

8

Synthesis and biological characterization of a promising F-18 PET tracer for vesicular acetylcholine transporter.

Tu Z, Zhang X, Jin H, Yue X, Padakanti PK, Yu L, Liu H, Flores HP, Kaneshige K, Parsons SM, Perlmutter JS. Tu Z, et al. Bioorg Med Chem. 2015 Aug 1;23(15):4699-4709. doi: 10.1016/j.bmc.2015.05.058. Epub 2015 Jun 5. Bioorg Med Chem. 2015. PMID: 26138195 Free PMC article.

9

Synthesis of Fluorine-Containing Phosphodiesterase 10A (PDE10A) Inhibitors and the In Vivo Evaluation of F-18 Labeled PDE10A PET Tracers in Rodent and Nonhuman Primate.

Li J, Zhang X, Jin H, Fan J, Flores H, Perlmutter JS, Tu Z. Li J, et al. Among authors: tu z. J Med Chem. 2015 Nov 12;58(21):8584-600. doi: 10.1021/acs.jmedchem.5b01205. Epub 2015 Oct 15. J Med Chem. 2015. PMID: 26430878 Free PMC article.

10

Chiral resolution of serial potent and selective σ₁ ligands and biological evaluation of (-)-[¹⁸F]TZ3108 in rodent and the nonhuman primate brain.

Yue X, Jin H, Luo Z, Liu H, Zhang X, McSpadden ED, Tian L, Flores HP, Perlmutter JS, Parsons SM, Tu Z. Yue X, et al. Among authors: tu z. Bioorg Med Chem. 2017 Feb 15;25(4):1533-1542. doi: 10.1016/j.bmc.2017.01.017. Epub 2017 Jan 16. Bioorg Med Chem. 2017. PMID: 28129990 Free PMC article.

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