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Page 1
SGLT2 expression in human vasculature and heart correlates with low-grade inflammation and causes eNOS-NO/ROS imbalance.
Mroueh A, Algara-Suarez P, Fakih W, Gong DS, Matsushita K, Park SH, Amissi S, Auger C, Kauffenstein G, Meyer N, Ohlmann P, Jesel L, Pieper MP, Marchandot B, Morel O, Mazzucotelli JP, Schini-Kerth VB. Mroueh A, et al. Among authors: auger c. Cardiovasc Res. 2024 Dec 31:cvae257. doi: 10.1093/cvr/cvae257. Online ahead of print. Cardiovasc Res. 2024. PMID: 39739876
Empagliflozin improved systolic blood pressure, endothelial dysfunction and heart remodeling in the metabolic syndrome ZSF1 rat.
Park SH, Farooq MA, Gaertner S, Bruckert C, Qureshi AW, Lee HH, Benrahla D, Pollet B, Stephan D, Ohlmann P, Lessinger JM, Mayoux E, Auger C, Morel O, Schini-Kerth VB. Park SH, et al. Among authors: auger c. Cardiovasc Diabetol. 2020 Feb 18;19(1):19. doi: 10.1186/s12933-020-00997-7. Cardiovasc Diabetol. 2020. PMID: 32070346 Free PMC article.
Angiotensin II-induced upregulation of SGLT1 and 2 contributes to human microparticle-stimulated endothelial senescence and dysfunction: protective effect of gliflozins.
Park SH, Belcastro E, Hasan H, Matsushita K, Marchandot B, Abbas M, Toti F, Auger C, Jesel L, Ohlmann P, Morel O, Schini-Kerth VB. Park SH, et al. Among authors: auger c. Cardiovasc Diabetol. 2021 Mar 16;20(1):65. doi: 10.1186/s12933-021-01252-3. Cardiovasc Diabetol. 2021. PMID: 33726768 Free PMC article.
COVID-19 promotes endothelial dysfunction and thrombogenicity: role of proinflammatory cytokines/SGLT2 prooxidant pathway.
Mroueh A, Fakih W, Carmona A, Trimaille A, Matsushita K, Marchandot B, Qureshi AW, Gong DS, Auger C, Sattler L, Reydel A, Hess S, Oulehri W, Vollmer O, Lessinger JM, Meyer N, Pieper MP, Jesel L, Bäck M, Schini-Kerth V, Morel O. Mroueh A, et al. Among authors: auger c. J Thromb Haemost. 2024 Jan;22(1):286-299. doi: 10.1016/j.jtha.2023.09.022. Epub 2023 Oct 4. J Thromb Haemost. 2024. PMID: 37797691 Free article.
Potential of dapagliflozin to prevent vascular remodeling in the rat carotid artery following balloon injury.
Matsushita K, Sato C, Bruckert C, Gong D, Amissi S, Hmadeh S, Fakih W, Remila L, Lessinger JM, Auger C, Jesel L, Ohlmann P, Kauffenstein G, Schini-Kerth VB, Morel O. Matsushita K, et al. Among authors: auger c. Atherosclerosis. 2024 Oct;397:117595. doi: 10.1016/j.atherosclerosis.2024.117595. Epub 2024 May 23. Atherosclerosis. 2024. PMID: 38879387 Free article.
Empagliflozin prevents angiotensin II-induced hypertension related micro and macrovascular endothelial cell activation and diastolic dysfunction in rats despite persistent hypertension: Role of endothelial SGLT1 and 2.
Bruckert C, Matsushita K, Mroueh A, Amissi S, Auger C, Houngue U, Remila L, Chaker AB, Park SH, Algara-Suarez P, Belcastro E, Jesel L, Ohlmann P, Morel O, Schini-Kerth VB. Bruckert C, et al. Among authors: auger c. Vascul Pharmacol. 2022 Oct;146:107095. doi: 10.1016/j.vph.2022.107095. Epub 2022 Aug 6. Vascul Pharmacol. 2022. PMID: 35944842 Free article.
EPA:DHA 6:1 is a superior omega-3 PUFAs formulation attenuating platelets-induced contractile responses in porcine coronary and human internal mammary artery by targeting the serotonin pathway via an increased endothelial formation of nitric oxide.
Zgheel F, Perrier S, Remila L, Houngue U, Mazzucotelli JP, Morel O, Auger C, Schini-Kerth VB. Zgheel F, et al. Among authors: auger c. Eur J Pharmacol. 2019 Jun 15;853:41-48. doi: 10.1016/j.ejphar.2019.03.022. Epub 2019 Mar 13. Eur J Pharmacol. 2019. PMID: 30878386
501 results