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27 results

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Cancer Organoids as reliable disease models to drive clinical development of novel therapies.
Blandino G, Satchi-Fainaro R, Tinhofer I, Tonon G, Heilshorn SC, Kwon YJ, Pestana A, Frascolla C, Pompili L, Puce A, Iachettini S, Tocci A, Karkampouna S, Kruithof-de Julio M, Tocci P, Porciello N, Maccaroni K, Rutigliano D, Shen X, Ciliberto G. Blandino G, et al. Among authors: iachettini s. J Exp Clin Cancer Res. 2024 Dec 28;43(1):334. doi: 10.1186/s13046-024-03258-7. J Exp Clin Cancer Res. 2024. PMID: 39731178 Free PMC article.
TRF2 as novel marker of tumor response to taxane-based therapy: from mechanistic insight to clinical implication.
Iachettini S, Terrenato I, Porru M, Di Vito S, Rizzo A, D'Angelo C, Petti E, Dinami R, Maresca C, Di Benedetto A, Palange A, Mulè A, Santoro A, Palazzo A, Fuso P, Stoppacciaro A, Vici P, Filomeno L, Di Lisa FS, Arcuri T, Krasniqi E, Fabi A, Biroccio A, Zizza P. Iachettini S, et al. J Exp Clin Cancer Res. 2024 Mar 9;43(1):75. doi: 10.1186/s13046-024-02998-w. J Exp Clin Cancer Res. 2024. PMID: 38459559 Free PMC article.
Erratum: identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities.
Rizzo A, Iachettini S, Zizza P, Cingolani C, Porru M, Artuso S, Stevens M, Hummersone M, Biroccio A, Salvati E, Leonetti C. Rizzo A, et al. Among authors: iachettini s. J Exp Clin Cancer Res. 2015 Feb 5;34(1):9. doi: 10.1186/s13046-014-0101-x. J Exp Clin Cancer Res. 2015. PMID: 25886908 Free PMC article. No abstract available.
The telomeric protein TERF2/TRF2 impairs HMGB1-driven autophagy.
Iachettini S, Ciccarone F, Maresca C, D' Angelo C, Petti E, Di Vito S, Ciriolo MR, Zizza P, Biroccio A. Iachettini S, et al. Autophagy. 2023 May;19(5):1479-1490. doi: 10.1080/15548627.2022.2138687. Epub 2022 Oct 30. Autophagy. 2023. PMID: 36310382 Free PMC article.
Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells.
Iachettini S, Trisciuoglio D, Rotili D, Lucidi A, Salvati E, Zizza P, Di Leo L, Del Bufalo D, Ciriolo MR, Leonetti C, Steegborn C, Mai A, Rizzo A, Biroccio A. Iachettini S, et al. Cell Death Dis. 2018 Sep 24;9(10):996. doi: 10.1038/s41419-018-1065-0. Cell Death Dis. 2018. PMID: 30250025 Free PMC article.
On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts.
Iachettini S, Stevens MF, Frigerio M, Hummersone MG, Hutchinson I, Garner TP, Searle MS, Wilson DW, Munde M, Nanjunda R, D'Angelo C, Zizza P, Rizzo A, Cingolani C, De Cicco F, Porru M, D'Incalci M, Leonetti C, Biroccio A, Salvati E. Iachettini S, et al. J Exp Clin Cancer Res. 2013 Sep 19;32(1):68. doi: 10.1186/1756-9966-32-68. J Exp Clin Cancer Res. 2013. PMID: 24330541 Free PMC article.
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